Abstract: A plication lock delivery system that enables a suture lock assembly to be delivered percutaneouly. The plication lock delivery system comprises a lock assembly that secures sutures in place, a control assembly that allows a clinician to engage a suture to a suture lock assembly, apply tension to the sutures to cause tissue plication, and deploy the lock assembly, and a catheter assembly. This plication lock delivery system can be used to repair mitral regurgitation percutaneouly or in an open-heart surgery.

Abstract: The disclosure provides an implantable medical device comprising a material capture element, which has a generally closed conical deployed shape and a narrow end disposed at or proximate the first end of the device. The material capture element includes a wide end facing the second end of the device, the material capture element having a zone of wider radial dimension which provides a first vessel contact site. A plurality of wire tethers are coupled to the wide end and extend to the second end. The wire tethers define a substantially open passageway for blood and provide a second vessel contact site. The first and second contact sites are spaced longitudinally from one another to provide stability. A first retrieval element is disposed at the first end and coupled to the narrow end, while a second retrieval element is disposed at the second end and coupled to the wire tethers.

Abstract: Apparatus and methods are described herein for use in the transfemoral delivery and deployment of a prosthetic mitral valve. In some embodiments, a method includes inverting an outer frame of a prosthetic mitral valve when in a biased expanded configuration. After inverting the outer frame, the prosthetic mitral valve is inserted into a lumen of a delivery sheath such that the mitral valve is moved to a collapsed configuration. The delivery sheath is inserted into a femoral vein and moved through the femoral vein and a septum of a heart until a distal end of the delivery sheath is disposed in the left atrium of the heart. The prosthetic mitral valve is moved distally out of the delivery sheath such that the inverted outer frame reverts and the prosthetic mitral valve assumes its biased expanded configuration. The prosthetic mitral valve is then positioned within a mitral annulus of the heart.

Abstract: An occlusion system (5) provides a trimmable continuous embolic coil (10) that is “cut to length” at the end of its deployment into the target occlusion site. A delivery device (15) provides the “cut to length” feature for the continuous embolic coil.

Abstract: The bifurcated forceps include a first pair of forceps having a first pair of opposed forceps or pincer arms and a second pair of opposed forceps or pincer arms. Each arm has a pivot end and a gripping end. Each pair is coupled at the pivot end and resiliently biased to a spaced apart position at the gripping end so that each pair may be independently pinched together, defining a gripping plane. The pivot ends of the two pairs are rotatable about a common pivot axis in a plane normal to the gripping planes, the arms in each pair being constrained to rotate to an identical radial angle in order to grip the same object at spaced apart positions. Adjacent arms in different pairs may have a mating blade and receptacle configuration to releasably lock the arms together to use the two pairs as a single pair.

Abstract: Examples of a suture anchor having a small diameter and having a soft suture bridge or suture eyelet are described herein. The soft suture bridge/suture eyelet allows a repair suture to slide, which is desirable when tying knots. In some cases, the soft suture bridge/suture eyelet itself is made from a length of suture.

Abstract: The present invention is an implantable adhesive mesh prosthesis for reinforcing and/or repairing a defect in tissue that is easy to roll into a small diameter cylinder or other low-profile shape for passing through a trocar, incision, or other surgical instrument. More specifically, the adhesive may be applied to the mesh material in a pattern that leaves a significant portion of the surface area of the mesh material free of adhesive. In one embodiment, the adhesive is applied only near the outer perimeter of the mesh product. In another embodiment, the adhesive is applied in spots over all or a portion the surface of the mesh product. In yet another embodiment, the adhesive is applied in parallel lines on the surface of the mesh product and the mesh may be rolled up around an axis parallel to the lines of adhesive.

Abstract: This invention relates generally to an endoluminal prosthesis, and more particularly, to a stent graft assembly and method for treating branched vessels. The assembly includes a first prosthesis, such as an iliac branch device (IBD), comprising a tubular main body, a first leg extending from a distal end of the main body and at least one fenestration formed in the main body. An internal tubular side branch extends proximally from the fenestration into the lumen of the main body, resulting in an iliac branch device having an overall reduced proximal length. The assembly further includes a second prosthesis, or a bridging limb, having a distal end with a scalloped fenestration formed therein to accommodate sealing with the proximal end of the iliac branch device without interfering with the internal branch. A connecting stent graft adapted for placement in the internal iliac artery may be sealingly connected to the internal branch.

Abstract: Catheters for the removal of occlusions in a patient's vasculature. Exemplary catheters use a flexible distal end tube which is capable of coiling irregularly within the occlusion and securing it for removal.

Abstract: A lancing device has a charging mechanism that operates to convert an external push action by a user to an internal pull action that retracts and charges a lancet for use in a lancing stroke. In some embodiments, the charging mechanism includes a user-actuated charging push-button, a reverse charging member coupled to a lancet carrier, and a reverse-motion conversion member coupled therebetween. Depressing the user-actuated member in a first longitudinal direction causes transverse movement of the conversion member, which in turn causes longitudinal retraction of the reverse charging member and the lancet carrier coupled thereto in a second longitudinal direction opposite the first direction, thereby charging a drive mechanism of the lancing device. In other embodiments, a rack-and-pinion gear mechanism provides the same push-to-pull functionality.

Abstract: The medical device disclosed here is configured to remove a plurality of objects at a time from an interior of a living body by restricting the objects from dropping out from an interior of a basket and is capable of treating objects in a body tissues having different structures efficiently with the same device. A treatment portion of a medical device includes an outer basket and an inner basket. A plurality of outer leg portions of the outer basket and a plurality of inner leg portions of the inner basket are arranged so as to be staggered in a circumferential direction. The medical device may be used by being switched between a mode of using only the outer basket and a mode of using both of the outer basket and the inner basket.

Abstract: This invention relates to medicine, more specifically, to the surgical treatment of intestinal obstructions using the minimum invasive (endoscopic) method. The invention provides the possibility of the surgical treatment of intestinal obstructions along the entire length of the intestine by means of stenting. The technical result achieved by the first and second subjects of the invention is providing the total surgical treatment of intestinal obstructions in the narrow and large intestine by installing a stent at an intestine obstruction location in a manner allowing further moving the stent during its positioning or removal and avoiding damage to the intestine as a result of the surgical manipulations. Said technical objective is achieved with the first subject of the invention, i.e. the method, as follows.

Abstract: Among other things, methods and apparatus for inserting devices for closing a tissue opening are disclosed. An anchoring or sealing member has one or more stems and/or filaments that are offset from the center of the member, so that lateral adjustments or movements of the anchoring or sealing member do not uncover the opening, cause the anchoring or sealing member to stick through or pull through the opening. Embodiments including a valve adapted to accommodate a guide wire for addressing emergencies are also disclosed.

Abstract: An ultrasonic probe includes a hook curved relative to a probe main body in a first perpendicular direction and forming a part of a distal surface, and a first base surface extending toward a proximal direction from a hook proximal end and serving as a base plane of the hook. The ultrasonic probe includes a protrusion protruding toward a second perpendicular direction with a second base surface, which is directed in a second perpendicular direction opposite to the first perpendicular direction, being as a base plane and extending toward both the proximal direction and a distal direction from a reference position located on a section, which passes through the hook proximal end and which is perpendicular to a longitudinal axis.

Abstract: The present invention relates to a prosthesis (1) intended to be implanted at an implantation site, comprising means of information (5) intended to guide the surgeon for performing the implantation of the prosthesis according to a defined arrangement, said prosthesis comprising at least one porous textile (2) having two faces (3,4) separated by a certain thickness, said means of information comprising at least one seam (5) provided in said textile, said seam traversing the thickness of said textile from one face to the other of said textile while preserving said thickness of said textile, said seam defining a zigzag pattern on at least one face of the textile.

Abstract: A uterine manipulator operable to detach the uterus and cervix from the vagina. The uterine manipulator includes an umbrella-like tip that creates a secure connection between the uterine manipulator and the uterus and cervix. The uterine manipulator also includes a pneumooccluder that enables rotation of the manipulator shaft while maintaining pneumoperitoneum. The uterine manipulator further includes a cutter that travels in a circle at the junction of the cervix and the vagina, permitting detachment of the uterus and cervix from the top of the vagina.

Abstract: Medical devices and methods for making and using medical devices are disclosed. An example medical device may include a guide extension catheter. The guide extension catheter may include a proximal tubular member having a lumen defined therein. A distal tubular member may be attached to the proximal tubular member. The proximal tubular member may have an outer diameter. The distal tubular member may have an inner diameter. The inner diameter of the distal tubular member may be greater than the outer diameter of the proximal tubular member. A stiffening member may be slidably disposed within the proximal tubular member.

Abstract: Disclosed is a micro-coil assembly including a micro-coil unit which is inserted into an aneurysm or other vascular malformation of a patient and prevents inflow of blood by inducing thrombus, a coil pusher unit which is arranged adjacent to the micro-coil unit and delivers the micro-coil unit to the aneurysm or other vascular malformation of the patient, a tensile wire which is relatively movably arranged in the coil pusher unit, a tie which connects the micro-coil unit and the tensile wire, and a tie cutting unit which is arranged adjacent to the coil pusher unit such that at least a part of the tie cutting unit is movable between a setting position for maintaining the tie in a tied state and a cutting position for cutting the tie, and cuts the tie when moved to the cutting position.

Abstract: An operating unit constituting a stent delivery system is provided with a first rotary roller having a first gear and a second rotary roller having a second gear. The first gear is meshed with a first tooth portion of a rack member and the second gear is meshed with a second tooth portion of the rack member. The first gear is formed to have a large diameter relative to the second gear and at the time of releasing a stent, after positioning a distal end of an outer tube body close to the stent through the rack member with the rotation of the first rotary roller of the operating unit, it is possible to move the outer tube body toward a proximal side at a lower speed than that in the previous state with the rotation of the second rotary roller.

Abstract: Surgical forceps for gripping internal organs during minimally invasive surgery are provided. The surgical forceps can be a sanitizable sheet in a folded configuration that includes a first elongate region which transitions to a resilient hinge which transitions to a second elongate region, all of which are formed of the same sheet. The first elongate region can further include a first grasper end opposite the resilient hinge and the second elongate region can include a second grasper end opposite the resilient hinge. The resilient hinge can apply a spring force to the first elongate region and the second elongate region that biases the forceps in an open configuration where the first grasper end and the second grasper end are distal from each other. When an external force is applied against the resilient hinge, the first grasper end can close against the second grasper end.