Patents Examined by Cherie Stanfield
  • Monoclonal antibodies with enhanced ADCC function
    Patent number: 9718890
    Abstract: The invention concerns a method for obtaining and selecting monoclonal antibodies by an ADCC-type test, said antibodies capable of activating type III Fcy receptors and having a particular glycan structure. The inventive anti-D antibodies can be used for preventing Rhesus isoimmunization in Rh negative persons, in particular for hemolytic disease in a new-born baby or for uses such as idiopathic thrombocytopenic purpura (ITP).
    Type: Grant
    Filed: April 1, 2015
    Date of Patent: August 1, 2017
    Assignee: Laboratoire Francais Du Fractionnement Et Des Biotechnologies
    Inventors: Roland Beliard, Dominique Bourel, Arnaud Glacet, Christophe De Romeuf, Nicolas Bihoreau, Emmanuel Nony