Abstract: A system for the intravascular placement of a medical device including a guidewire having a first end and a second end, the first end having a microwhisk positional between a feeding state and a deployed state, a guidewire sheath surrounding the guidewire; and an anchoring device for cooperatively fixing the microwhisk relative to a patient. Also, the method of the intravascular placement of the medical device by inserting the medical device through the body with the guidewire and the microwhisk contained within the guidewire sheath, driving the microwhisk out of the guidewire sheath to position the microwhisk to its deployed state, and engaging the anchoring device from the outside of the body through a body surface into the microwhisk, and further into a stabilizing body component.

Abstract: A method of deploying a stent device into an aorta of a patient includes positioning a distal portion of the stent device at least beyond the left subclavian artery into the descending aorta by axially translating a distal end of a rod of a deployment device into the aorta. The stent device is engaged with the deployment device in an initial configuration about the rod. The axial translation occurs in a direction extending from the aortic arch into the descending aorta. The stent device further includes a stent portion in fluid engagement with the distal portion. The stent portion and the distal portion define an uncovered open cell surface. The stent device further includes a proximal portion in fluid engagement with the stent portion. A collar is defined at a terminal end of the proximal portion.

Abstract: A surgical device comprising: (1) a handpiece having a distal end portion; (2) a tubular member extending from the distal end portion, the tubular member having a lumen therethrough, the lumen comprising: (a) a proximal lumen portion, (b) a distal lumen portion, (c) a first central lumen portion, and (d) a second central lumen portion, the second central portion being located between the proximal lumen portion and the first central lumen portion, wherein the distal lumen portion diverges as the distal lumen portion extends away from the first central lumen portion in a distal direction, and the second central lumen portion diverges as the second central lumen portion extends away from the first central lumen portion in a proximal direction and; wherein the tubular member has wall with a substantially uniform thickness about the first central lumen portion.

Abstract: A device (10) for repair of a heart valve leaflet includes an elongated body (12) having a lumen (16) extending therethrough in a longitudinal direction, a proximal end, an open distal end (19). A core (11) is disposed within the lumen, and is operable to spin about an axis extending in the longitudinal direction. The spinning of the core draws a portion of the heart valve leaflet into the lumen through the open distal end of the body and secures the portion of the heart valve leaflet to the core in a gathered configuration.

Abstract: Surgical devices and methods of soft tissue repair using pre-looped tensionable and non-pre-looped tensionable knotless fixation devices. A flexible material (for example, suture or suture tape) may be attached to the fixation device. A flexible material may be threaded through an eyelet of a tip provided as part of a swivel anchor assembly to provide added stability to the fixation devices.

Abstract: An assembly including a deployment device for deploying a stent device into an aorta of a patient is provided. The deployment device includes a rod translatable within an aorta of a patient and a first release wire configured for releasing one or more radially constraining members, wherein the radially constraining members are configured to constrain a diameter of the stent device. The stent device is at least partially permeable and engaged with the deployment device in an initial configuration, wherein a diameter and a length of the stent device in a deployed configuration can be altered by axial translation of the rod and releasing one or more of the radially constraining members by translation of the first release wire.

Abstract: An intravascular device is provided having a catheter tube and an expandable portion including a plurality of struts capable of being moved between an open and a closed position. An incising element is provided on at least one of the struts and has a sharpened edge for creating an incision in atherosclerotic material located within a blood vessel when the expandable portion is in the opened position. A medication delivery device may be located on one or more of the struts and may be configured to deliver a substance to an area of interest.

Abstract: A hub assembly for use with an endoscopic assembly of a reposable surgical clip applier includes an outer housing and a drive assembly supported within the outer housing. The drive assembly includes a cartridge cylinder slidably supported within the outer housing, a plunger translatably supported within the outer housing and slidably coupled to the cartridge cylinder, a first biasing element interposed between the cartridge cylinder and the outer housing, and a second biasing element interposed between the cartridge cylinder and the plunger. The first biasing element includes a first threshold and the second biasing element includes a second threshold that is greater than the first threshold. A force exceeding the first threshold causes the cartridge cylinder and plunger to translate simultaneously and a force exceeding the second threshold causes the cartridge cylinder to translate relative to the plunger.

Abstract: A delivery device can include several different features including, at least: a shuttle and trigger retraction of an outer sheath; an interlock device to prevent actuation of the trigger; a retraction override switch and lock; and an inner shaft adjuster to ensure correct alignment of the inner shaft and the outer sheath prior to device deployment. The inner shaft adjuster may include, at least: a proximal portion of the handle housing having slots therethrough: pins operatively fixed to the inner shaft and extending through and slidable within the slots: and a cap having an inner helical groove that mates with the pins. Rotation of the cap may push the pins and the inner shaft in a proximal-distal direction. The cap may have a distal lip configured to accept a proximal extension of the interlock and retain it in a locked position until the inner shaft has been adjusted or moved.

Abstract: A non-invasive cerebral perfusion increasing device including four cuffing pad units and a control unit which is connected to the cuffing pad units and is equipped with a blood pressure sensing module and a compression control module. In the non-invasive cerebral perfusion increasing device each cuffing pad unit respectively includes a compression pad, a compression control member and a blood pressure sensing member. The blood pressure sensing module uses the blood pressure sensing members to sense the systolic blood pressure values of the portions of each of the limbs where they are attached and the compression control module controls the degree of compression of each compression pad by controlling the compression control member to a setting desired by the user based on the sensed blood pressure value, such that the blood flow applied to the limbs is blocked and, indirectly, cerebral perfusion is increased.

Abstract: The invention relates to devices and methods for deploying an implant. Preferably the device (10) deploys a flexible implant in an eye. In one embodiment, the device comprises a distal end and a proximal end, wherein the distal end is constructed and arranged to cause said implant to be flexed into a curved configuration when in a carried position and the device is configured to urge said flexed implant from said carried position to a deployed position. Embodiments with removable tips (13) and wheel actuators (14) are also disclosed.

Abstract: A trocar sleeve for minimally invasive surgery, having a first sleeve part, which has essentially the shape of a straight tubular piece with a longitudinal axis, and having a second sleeve part, which at least partly surrounds the first sleeve part in close contiguity and is movable during use with respect to the first sleeve part. The mobility of the second sleeve part in relation to the first sleeve part consists essentially only in rotatability of the second sleeve part around the first sleeve part, and in addition the first sleeve part and the second sleeve part each comprise on their distal axial ends a flange part that extends radially outward at an angle of less than 180 degrees from the respective sleeve part.

Abstract: An ophthalmic surgical instrument includes a housing and a snare operably coupled to the housing. The snare is configured to transition between an insertion configuration and a deployed configuration, in which the snare is sized to encircle lenticular tissue. The ophthalmic surgical instrument is designed to prevent elevation and/or tilting of the lenticular tissue as the snare transitions toward the insertion configuration to divide the lenticular tissue.

Abstract: A surgical suturing instrument includes a handle assembly, a shaft extending distally from the handle assembly, and an end effector. The end effector includes a body portion coupled to the shaft, a first jaw member pivotably coupled to the body portion, and a second jaw member pivotably coupled to the body portion. The first jaw member is rotatable about a longitudinal axis defined by the body portion and defines a hole configured for detachable receipt of a curved needle. The second jaw member defines a hole configured for detachable receipt of a curved needle such that the first and second jaw members transfer a curved needle therebetween upon rotation of the first jaw member about the longitudinal axis of the body portion toward the second jaw member.

Abstract: A surgical instrument including a reusable and sterilizable hub assembly and a releasably connectable disposable blade assembly allows multiple reuse of the hub assembly in conjunction with single use disposable blade assemblies.

Abstract: Dislodgment of a constricting cord from an annulus can be prevented by delivering the distal loop portion of the constricting cord to the annulus using a percutaneous delivery tool, and launching anchors into the annulus so as to affix the distal loop portion of the constricting cord to the annulus. The percutaneous delivery tool is withdrawn in a proximal direction after the anchors have been launched. A pushing member is pressed in a distal direction so that the pushing member holds a portion of the constricting cord against the annulus with enough pressure to prevent dislodgment of any of the anchors during the withdrawal of the percutaneous delivery tool.

Abstract: A medical instrument includes: a rod including a curving portion formed on a distal side of an extension along a longitudinal axis and curved with respect to the longitudinal axis; and a sheath including an inner peripheral surface and a cutout, the cutout formed in at least one of a distal portion and a proximal portion of the sheath, the sheath configured to insert the rod along a central axis extending and defined from the distal portion to the proximal portion and to protrude the curving portion from an opening of the inner peripheral surface in the distal portion.

Abstract: An intravascular device is provided having a catheter tube and an expandable portion including a plurality of struts supported in a cantilevered fashion so as to be splayed open when in an opened position. An incising element is provided on at least one of the struts and has a sharpened edge for creating an incision in atherosclerotic material located within a blood vessel when the expandable portion is in the opened position.

Abstract: An intravascular device is provided having a catheter tube with an expandable portion located on an end thereof. The expandable portion includes a plurality of struts capable of being moved between an open and a closed position. An incising element is provided along at least a portion of one of the struts and has a sharpened edge for creating an incision in atherosclerotic material located within a blood vessel when the expandable portion is in the opened position.

Abstract: The present invention relates to substantially compressible, spherical porous embolization particles, including methods of making and using the particles. Methods of using the particles include methods of embolization, in which at least one particle can be positioned in a target area of a blood vessel. The particles can also include interior pores that extend to the surface of the particles. Further, the invention relates to embolization delivery systems for the introduction of the particle into the vascular luer.