Abstract: For the determination of the rate of nucleic acid synthesis in eukaryotic cells a nucleotide which is non-radioactively labelled or derivatized with a hapten is introduced into the cells with the addition of liposomes and the rate of synthesis of the nucleic acids is determined by means of the incorporation of the nucleotide via its label or derivatization.
Type:
Grant
Filed:
April 19, 1994
Date of Patent:
October 3, 1995
Assignee:
Boehringer Mannheim GmbH
Inventors:
Matthias Hinzpeter, Herbert von der Eltz