Patents Examined by Choon P. Koh
  • Patent number: 4990332
    Abstract: The subject invention concerns a novel and useful insecticide with activity against insect pests of the order Lepidoptera. Pests in the order Lepidoptera do heavy damage to crops, e.g., cabbage and broccoli. The insecticide of the subject invention is a novel B. thuringiensis microbe referred to as B.t. PS85A1, or mutants thereof. Specifically disclosed is an asporogenous mutant designated B.t. PS85A1-168. The spores or crystals of B.t. PS85A1, or the crystals of B.t. PS85A1-168, are useful to control lepidopteran pests in various environments.
    Type: Grant
    Filed: October 25, 1988
    Date of Patent: February 5, 1991
    Assignee: Mycogen Corporation
    Inventors: Jewel Payne, George G. Soares, Henry W. Talbot, Theresa C. Olson
  • Patent number: 4981844
    Abstract: The immune response of a patient can be improved pre-operatively by altering the diet of a patient. When 20 to about 80% of the calories in a diet are from linoleic acid which is an omega 6 fatty acid, the immune response system and resistance to infection of the patient is substantially improved. Likewise providing 100 to about 1,000 IU per day of vitamin E in the diet also improves the immune response of the patient pre-operatively. This in turn improves the survival rate of the patient.
    Type: Grant
    Filed: October 4, 1988
    Date of Patent: January 1, 1991
    Assignee: University of Cincinnati
    Inventors: J. Wesley Alexander, Michael D. Peck
  • Patent number: 4959350
    Abstract: An enteral diet composition which comprises a balanced diet aqueous medium mixture of fat, carbohydrate, and dietary nitrogen compounds characterized by a total energy content of at least about 0.68 kcal/ml, an osmolality of below about 350 milli-osmol and a pH lower than about 4.5. The dietary nitrogen compounds are at least about 95% soluble in the aqueous medium and are free from bitterness in the composition. At least about 50% of the dietary nitrogen compounds is derived from vegetable protein source(s).The enteral diet product exhibits a combination of advantageous characteristics, i.e., good microbiological stability, good physical stability of the emulsion, low osmolality, satisfactory organoleptic properties, and satisfactory nutritional and handling properties.
    Type: Grant
    Filed: April 15, 1987
    Date of Patent: September 25, 1990
    Assignee: Novo Industri A/S
    Inventors: Sven Frokjaer, Svend Eriksen, Jens L. Adler-Nissen
  • Patent number: 4957902
    Abstract: The present invention involves the inhibition of wound contraction by polypeptides having an amino acid sequence which is similar or identical to certain amino acid sequences of type (I) collagen. A variety of peptides are disclosed which are clinically useful as inhibitors of wound contraction.
    Type: Grant
    Filed: December 20, 1988
    Date of Patent: September 18, 1990
    Assignee: Board of Regents, the University of Texas System
    Inventor: Frederick Grinnell
  • Patent number: 4935494
    Abstract: Methodology involving novel coupling reagents for the carboxyl-terminal amino acid sequence analysis of peptides and proteins is described.
    Type: Grant
    Filed: November 15, 1988
    Date of Patent: June 19, 1990
    Assignee: City of Hope
    Inventor: Chad G. Miller
  • Patent number: 4931546
    Abstract: Collagen is submitted to a controlled oxidation by treatment with a solution of periodic acid or of a periodate, notably of sodium. Application to gels, implants, lenses, films, spheres, etc., of collagen.
    Type: Grant
    Filed: July 13, 1987
    Date of Patent: June 5, 1990
    Assignees: Imedex, Institut Merieux
    Inventors: Michel Tardy, Jean-Louis Tayot
  • Patent number: 4925662
    Abstract: Disclosed herein are an anti-tumor substance obtained by bonding an anti-tumor agent to human immunoglobulin, and a process for producing the same.
    Type: Grant
    Filed: January 14, 1988
    Date of Patent: May 15, 1990
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Yoshiharu Oguchi, Koichi Niimura, Takayoshi Fujii, Masahiko Fujii, Kenichi Matsunaga, Chikao Yoshikumi
  • Patent number: 4892731
    Abstract: Cells or endospores of a butyric-acid bacterium Clostridium butyricum MII588-Sens 1 strain, or cells or endospores of a butyric-acid bacterium Clostridium butyricum MII588-Res 1 strain are effective as a biological intestinal antiseptic.
    Type: Grant
    Filed: August 9, 1988
    Date of Patent: January 9, 1990
    Assignee: Tadashi Arai
    Inventors: Tadashi Arai, Mamoru Tanaka, Akio Maeda
  • Patent number: 4891359
    Abstract: A hemostatic collagen paste composition comprising a mixture, by weight of the total composition, of 2 to 30% of crosslinked collagen powder of 10 to 100 mesh particle size and 30 to 98% of water or an aqueous saline solution and hemostatic paste compositions that also comprise a hemostatic enhancing amount of thrombin, as well as methods of making and using such hemostatic collagen paste compositions.
    Type: Grant
    Filed: December 8, 1988
    Date of Patent: January 2, 1990
    Assignee: Johnson & Johnson Patient Care, Inc.
    Inventors: Lowell Saferstein, Stephen J. Wolf
  • Patent number: 4889920
    Abstract: A cold water-soluble instantized gelatin having full gelation ability while containing no additives is obtained by spraying a pure gelatin solution without additives and having a water content of at least 35% at a temperature in excess of the gelation and solidification temperature on an excess of finely divided solid gelatin particles which contain less than 8% of water, and drying the particles thus obtained in a fluid bed to a water content of from 8 to 13%, whereupon a portion is removed from the process as final product and is further dried to a water content as required for optimum dissolution to occur in cold water, while the remainder first is more effectively dried to a water content below 8% and is then recycled into the process.
    Type: Grant
    Filed: August 8, 1988
    Date of Patent: December 26, 1989
    Assignee: Deutsche Gelatinefabriken Stoess & Co. GmbH
    Inventor: Alexander Muller
  • Patent number: 4885275
    Abstract: Gel-free concentrated aqueous formulations of vancomycin hydrochloride are provided which comprise the antibiotic salt at a concentration between about 12% and about 50% w/v and a gel-inhibiting compound, e.g., ethanol, at a concentration between about 1% and about 20% v/v. The gel-free formulations are especially useful in a freeze-drying process for preparing vancomycin hydrochloride as a dry flowable powder in bulk or in unit-dosage form.
    Type: Grant
    Filed: October 15, 1987
    Date of Patent: December 5, 1989
    Assignee: Eli Lilly and Company
    Inventor: Robert L. Robison