Abstract: Described are methods and devices for improving diastolic function with electrostimulation in heart failure patients who exhibit relatively normal systolic function. Such patients are characterized by impaired myocardial relaxation during diastole that prevents adequate filling of the ventricles during diastole to thereby reduce cardiac output. An implantable device is described for effecting strategic and periodic stimulation of the sympathetic nervous system to elicit myocardial adrenergic activation for improved myocardial relaxation.
Type:
Grant
Filed:
February 2, 2011
Date of Patent:
July 30, 2013
Assignee:
Cardiac Pacemakers, Inc.
Inventors:
Allan C. Shuros, Shantha Arcot-Krishnamurthy, Guy Alvarez