Abstract: The present invention relates to methods and kits useful for guiding the administration of a therapeutic agent in a subject afflicted with, or believed to be afflicted with osteoporosis.
Abstract: Compositions and methods for treating neural pathologies are provided. In particular, compositions and methods for treating neural pathologies including axonal degeneration are provided. The compositions include peptide ?-ketomides optionally in combination with a second therapeutic agent. Another aspect of the invention provides compositions and methods for treating hyperproliferative disorders. Exemplary compositions for treating hyperproliferative disorders include an anti-proliferative agent such as paclitaxel, in combination with a calpain inhibitor such as AK295.
Type:
Grant
Filed:
September 25, 2003
Date of Patent:
September 30, 2008
Assignees:
Georgia Tech Research Corporation, Emory University
Abstract: The present invention provides compositions and methods related to the expression of Bowman-Birk protease inhibitors and variants thereof in bacterial species. The present invention further provides fusion nucleic acids, vectors, fusion polypeptides, and processes for obtaining the Bowman-Birk protease inhibitors.
Type:
Grant
Filed:
November 8, 2004
Date of Patent:
August 19, 2008
Assignee:
Genencor International, Inc.
Inventors:
Katherine Collier, Grant Ganshaw, Hans De Nobel, Scott D. Power, Anita Van Kimmenade, Marc Kolkman, Jeffrey Miller, Brian Schmidt, Gudrun Vogtentanz, David Estell