Abstract: The present invention relates to methods for remotely and intelligently tuning movement disorder of therapy systems. The present invention still further provides methods of quantifying movement disorders for the treatment of patients who exhibit symptoms of such movement disorders including, but not limited to, Parkinson's disease and Parkinsonism, Dystonia, Chorea, and Huntington's disease, Ataxia, Tremor and Essential Tremor, Tourette syndrome, stroke, and the like. The present invention yet further relates to methods of remotely and intelligently or automatically tuning a therapy device using objective quantified movement disorder symptom data to determine the therapy setting or parameters to be transmitted and provided to the subject via his or her therapy device. The present invention also provides treatment and tuning intelligently, automatically and remotely, allowing for home monitoring of subjects.

Abstract: A kit-of-parts for initiating an action by an active implantable medical device (AIMD) (1) implanted in a body of a patient triggered by an external triggering unit (11) located outside the body of the patient is provided. The kit-of-parts including, (A) the external triggering unit (11) including an external emitter (12) which includes one or more sources of light (12L) configured for emitting an optical starting signal (10), and (B) the AIMD (1) including an encapsulation unit (1e) defining an inner volume containing an action trigger configured for initiating an action by the AIMD (1), upon reception of the optical starting signal (10) from the external triggering unit (11). The action trigger is an optical action trigger (2) includes one or more photodetectors (2pv) facing a transparent wall portion (1t) and configured for transforming the optical starting signal (10) into an electrical signal to initiate the action by the AIMD.

Abstract: Methods and apparatus for the treatment of a body cavity or lumen are described where a heated fluid and/or gas may be introduced through a catheter and into treatment area within the body contained between one or more inflatable/expandable members. The catheter may also have optional pressure sensing elements which may allow for control of the pressure within the treatment zone and also prevent the pressure from exceeding a pressure of the inflatable/expandable members to thereby contain the treatment area between these inflatable/expandable members. Optionally, a chilled or room temperature fluid such as water may then be used to rapidly terminate the treatment session.

Abstract: A bioinformation acquiring apparatus includes at least one processor and a memory configured to store a program to be executed in the processor.

Abstract: A system and method for monitoring the state of an individual. The method includes providing a stimulus to the individual, measuring a response to the provided stimulus, comparing the measured response to an expected response, and diagnosing one or more aspects of disease in accordance with the result of the comparison between the measured response and the expected response. The stimulus may be a predetermined test sequence, such as a visually displayed predetermined sequence of images, or may include observation of the physical response of the individual while performing one or more predetermined activities. Stored images or video of the individual responding to one or more test sequences may be stored in a lossy or lossless state, and thus security and de-identification may be provided to stored data. This stored data may also be de-identified in a manner to allow for the answering of the greatest number of future questions.

Abstract: A method of creating an AV fistula between adjacent first and second vessels includes inserting a guidewire from the first vessel into the second vessel. Inserting a catheter including a proximal member and a distal member over the guidewire such that a distal tip of the distal member comes into contact with a selected anastomosis site. Moving the distal member and the proximal member together to clamp tissue surrounding the aperture between the distal face of the proximal member and a proximal face on the distal member. Applying energy to an active heating member on the proximal member to cut and form the aperture, and to weld the edges thereof in order to create a desired fistula between the two vessels. Using a passive heating member disposed on the distal member to create a heating gradient across a tissue contacting surface of the distal member.

Abstract: An ophthalmological apparatus comprises a laser source for producing a pulsed laser beam, a scanner system for deflecting the pulsed laser beam at a treatment speed in the eye tissue along a scanning treatment line, a first scanning apparatus connected upstream of the scanner system for deflecting the pulsed laser beam and for producing a first scanning movement component superposed on the scanning treatment line in a first scanning direction at a first scanning speed that is higher as compared to the treatment speed, and a second scanning apparatus connected upstream of the scanner system for deflecting the pulsed laser beam and for producing a second scanning movement component, which is superposed on the first scanning movement component in a second scanning direction, which is at an angle to the first scanning direction, at a second scanning speed that is higher as compared to the first scanning speed.

Abstract: Systems and method to measure pressure are described herein. The system can include a force sensor can that be implanted into a patient to measure, for example, cardiac pressure. The force sensor can include first and second film layers that can define a plurality of pressure cells. An external pressure can deform the pressure cells and change their resonant frequency. When exposed to an acoustic signal, the pressure cells can resonant at a pressure-dependent resonant frequency. The system can detect reflected acoustic waves generated by the resonance of the pressure cells. The system can convert the frequency readings into pressure values.

Abstract: A heart assist device comprising a rotary pump housing having a cylindrical bore, a pumping chamber and a motor stator including an electrically conductive coil located within the housing and surrounding a portion of the cylindrical bore. A rotor has a cylindrical shaft with an impeller and one or of magnets located within the shaft that are responsive to the motor stator to drive actuation of the rotor. The housing bore is closely fitted to the outer surface of the shaft forming a hydrodynamic journal bearing with an annular clearance defining a leakage flow path. One or more of radial or axial thrust bearings may be provided to provide rotation stability to the rotor and flow within the leakage flow path. The relative orientation of positions of the inflow, outflow, and leakage flow paths may be varied within the pump, such as to accommodate different intended methods for implantation and/or use.

Abstract: In various embodiments, an electronic device may include: a light receiver including light receiving circuitry, a light emitter including light emitting circuitry, a partition wall disposed between the light receiver and the light emitter configured to block light emitted by the light emitter from being directly incident on the light receiver, a film disposed above one surface of the light receiver, and a processor. The film may include a transmission region configured to transmit light of all wavelength bands and a selective blocking region configured to absorb light of a specific wavelength band. The processor may be configured to analyze light incident on the light receiver through the film.

Abstract: Systems and methods for determining whether a user employs System 1 type thinking or System 2 type thinking when engaged in a task are disclosed. The systems and methods include determining one or more properties of the task based on information regarding the task received from a database storing information regarding the task, determining one or more properties of the user with respect to the task, determining a state of the user based on one or more physiological sensors configured to sense one or more characteristics of the user, and determining that the user employs System 1 type thinking or System 2 type thinking when engaged in the task based on the determined one or more properties of the task, the determined one or more properties of the user, and the determined state of the user.

Abstract: Provided herein are a variety of neural probe devices that include an agent delivery feature via an agent coating or an agent delivery mechanism of some kind. The probe devices can include depth or cortical probes or electrodes. The agent delivery mechanisms can include, for example, a dissolvable agent delivery structure, an agent delivery lumen, a magnetically deployable cover, an iontophoretic delivery mechanism, an agent delivery cavity defined in the neural probe, or an agent reservoir with an actuable gate.

Abstract: A non-invasive bodily-attached ambulatory medical monitoring and treatment device with pacing is provided. The noninvasive ambulatory pacing device includes a battery, at least one therapy electrode coupled to the battery, a memory storing information indicative of a patient's cardiac activity, and at least one processor coupled to the memory and the at least one therapy electrode. The at least one processor is configured to identify a cardiac arrhythmia within the information and execute at least one pacing routine to treat the identified cardiac arrhythmia.

Abstract: A medical device is disclosed, including a handle assembly; an elongate body coupled to the handle assembly, the elongate body defining a guide wire lumen therethrough; and a substantially semi-circular electrode array coupled to the elongate body. The device may include a substantially rigid shaft extending distally from the elongate body and defining a lumen therethrough, the shaft including a substantially rigid segment, and a flexible coil coaxial with and extending distally from the shaft.

Abstract: Neuromodulation of cranial nerves can be used to treat sleep or breathing disorders, among other diseases and disorders. A neuromodulation system can include a housing configured for implantation in an anterior cervical region of a patient, such as at or under a mandible of the patient, such as at least partially in one or more of a submental triangle, a submandibular triangle, and a carotid triangle. The system can include an electrode lead coupled to the housing, and the electrode lead can include an electrode configured to be disposed at or near a cranial nerve target in the patient. The system can be configured to generate electrical neuromodulation signals for delivery to the cranial nerve target using the electrode.

Abstract: The present system combines, on a host server, clinician software for accessing a case history database of past results/feedback from users seeking stimulation therapy, other users within a member network and other users outside the member network and pharmacy software for generating, in the form of a database, an expert system/artificial intelligence program and signal processing software, stimulation waveforms required by the users according to prescriptions from clinicians (completed by clinical experts/server knowledge software) and/or pain points indicated by the users, wherein an innovative open terminal data format and file format and an innovative high-efficiency frequency band waveform compression technique are used.

Abstract: A system is provided including an implantable device configured to be implanted subcutaneously within a patient, a clinician monitoring and control device, an optional patient mobile device, a remote server and/or at least one data analyst device used by a data analyst. The implantable device may communicate with any or all of the monitoring and control device, the mobile device and/or the remote server through the charging device or by establishing a direct wireless connection with each such device. The data analyst device may establish a direct connection with the remote server and also may establish a connection with the monitoring and control device and the mobile device. By analyzing and reviewing the data generated by the implantable device, the data analyst may diagnose a medical condition or indicate a heightened risk of a condition.

Abstract: A fatigue state determination device and a fatigue state determination method determine a fatigue state of a subject. The fatigue state determination device includes a brain-function activation information provision unit and a fatigue state determination unit. The brain-function activation information provision unit provides brain-function activation information in order to activate a human brain function of a subject. The fatigue state determination unit determines a fatigue state of the subject based on facial-surface change information indicative of a time-series change of facial surface data on the subject while the brain-function activation information is being provided.

Abstract: A surgical feedback system includes a surgical instrument, a data source, and a surgical hub configured to communicably couple to the data source and the surgical instrument. The surgical hub has a control circuit, wherein the control circuit is configured to receive an input from the data source, analyze the received data against a stored set of data to optimize an outcome of a surgical procedure, and communicate a recommendation based on the analyzed data.

Abstract: Methods and systems for analyzing care data are described. The method includes building a virtual model of a physical medical device. Training is provided to a patient associated with the physical medical device to properly use the physical medical device by manipulating the virtual model. First care data associated with a first sensor associated with the physical medical device and second care data associated with a second sensor is received by a cloud service. The cloud service analyzes the first care data to obtain a first care data score and analyzes the second care data to obtain a second care data score. The cloud service scores, using a machine learning algorithm, the first care data score and the second care data score to obtain a combined care score. The cloud service determines whether the combined care score is greater than a threshold. The cloud service triggers an emergency procedure when it is determined that the combined care score is greater than the threshold.