Abstract: An orthopaedic joint replacement system is shown and described. The system includes a number of prosthetic components configured to be implanted into a patient's knee. The system also includes a number of surgical instruments configured for use in preparing the bones of the patient's knee to receive the implants. A number of methods for using the surgical instruments to prepare the bones is also disclosed.

Abstract: A knee joint endoprosthesis set including modular knee joint endoprostheses in different sizes. Each knee joint endoprosthesis includes a tibial component. The femoral component includes a joint element for articulated cooperation with the tibial component and comprises a shaft for anchoring in the femur. The set includes shafts in different sizes. In the femoral component, the shape of the shafts tapers from a distal end, facing toward the joint element, to a proximal free end of the shaft. An oval cross-section is provided at the distal end, and a round cross-section is provided at the proximal free end of the shaft.

Abstract: Disclosed herein are gender-specific implantable mesh for inguinal hernia repair in a patient, comprising: a fabric layer comprising a side defining a surface area wherein the fabric layer is configured to enable tissue adhesion to said mesh; an anti-adhesive barrier comprising a shape configured to prevent direct contact between the fabric layer and both a spermatic cord and a genital nerve upon implantation, wherein the shape covers a part of the surface area on the side of the fabric layer, the part being less than 25%, and wherein the shape is oblique to a horizontally-oriented centerline and a vertically-oriented centerline; and a keyhole configured to fit the genital nerve and the spermatic cord of the patient therethrough without constriction, wherein the keyhole is oblique and inferior to a horizontally-oriented centerline and medial to a vertically-oriented centerline.

Abstract: A bifurcated dual-balloon catheter apparatus for deploying one or more stents to a bifurcated vessel or for use in angioplasty procedures involving bifurcated vessels. The apparatus is particularly suited for bifurcated vessels of the type having a main branch from which a side branch extends therefrom. The apparatus has a main branch balloon and a side branch balloon. A conduit is provided in the main branch balloon through which a portion of the side branch balloon extends. The first balloon is positionable within the main branch of the vessel while the distal portion of the second balloon is positionable within the side branch such that when the first and second balloons are inflated, the first balloon expands radially in the main branch while the distal portion of said second balloon maintains registration with the side branch by expanding radially therein.

Abstract: System, devices and methods for providing a blood-free operative region for aortic arch repair procedures. Various embodiments disclose occlusion of the descending aorta, the innominate artery, the left carotid artery and the left subclavian artery while also providing sufficient perfusion distal of the occluding balloons. Various embodiments disclose performing aortic arch repair procedures while the patient's body temperature is maintained an normothermia (about 36 degrees C to about 37.5 degrees C). Other embodiments disclose performing aortic arch repair procedures while the patient's body temperature is maintained at slight hypothermia (about 30 degrees C to about 34 degrees C).

Abstract: Light Adjustable Lenses (LALs) are described that suppress unintended optical power drift. These LALs comprise a polymer silicone network, infused with a mobile macromer, a non-switchable ultraviolet absorber, a photoinitiator, and a front protection layer, including a switchable ultraviolet absorber. The LAL is light adjustable by a shaped illumination activating the photoinitiator which induces a polymerization of the mobile macromer, thereby changing an optical power of the LAL. The LAL can accommodate an 0.5-20 ppm oxygen concentration; and a ratio of the oxygen concentration times an oxygen-driven photoinitiator quench rate over a mobile macromer concentration times a photoinitiator-driven polymerization add rate is greater than 10. Some of these LALs include a non-switchable ultraviolet absorber in the front protection layer; or a radical scavenger; or a monofunctional, or sterically hindered mobile macromer; or a switchable photoinitiator, or an anchored photoinitiator.

Abstract: Described herein is a device for an intervention of reconstruction of a cruciate ligament that includes a penetrator defining a first passage lumen, and a sleeve member coupled to the penetrator and defining a second passage lumen that is in communication with the first passage lumen. The penetrator is configured for being introduced into a tibial plate and for receiving a replacement cruciate ligament through the first passage lumen. The sleeve member is configured for receiving the replacement cruciate ligament through the second passage lumen.

Abstract: The invention relates to a method for draining a medical device adapted to be implanted in a human or animal body, said medical device comprising a housing that encloses a fluid reservoir, and a fluid outlet that forms a fluid connection between the reservoir and a volume outside the housing, the method involving: —providing the device in packaging comprising a tank, the housing being held in the tank in a position in which the reservoir is located between the bottom of the tank and the fluid outlet; —filling the tank with a biocompatible fluid such that a zone of the packaging which lies outside the medical device and is in fluid connection with the fluid outlet of the tank is immersed in the fluid; —draining the medical device and filling the reservoir with the biocompatible fluid.

Abstract: A system for implanting a prosthesis includes a control lumen and a nose cone affixed at a distal end of the control lumen. At least one supporting wire is affixed at one end, is substantially parallel to a major axis of the control lumen and is free at an opposite end, wherein the free end of at least one of the supporting wires is arcuate. Alternatively, a system for implanting a prosthesis includes at least one suture extending from a nose cone affixed to a distal end of a control lumen. The suture extends from the nose cone to a proximal end to a stent graft extending about the control lumen and from the stent graft to a fixed location on the control lumen. The suture is releasable from the stent graft by remote activation, whereby the suture separates from the nose cone to thereby deploy the stent graft.

Abstract: An orthopaedic joint replacement system is shown and described. The system includes a number of prosthetic components configured to be implanted into a patient's knee. The system also includes a number of surgical instruments configured for use in preparing the bones of the patient's knee to receive the implants. A number of methods for using the surgical instruments to prepare the bones is also disclosed.

Abstract: A pivotal bone anchor assembly includes a receiver having a lower cavity with a circumferential groove adjacent a bottom opening, an upper first channel with a downward-facing surface formed therein below a closure mating structure, and a substantially cylindrical surface extending below the downward-facing surface with an alignment stop structure. The assembly also includes a shank having a capture portion configured for uploading into the cavity through the bottom opening, and an open ring retainer uploadable into the circumferential groove through the bottom opening after the capture portion so as to retain the capture portion within the cavity.

Abstract: A sinus tarsi implant for the purpose of stabilizing and restoring motion between the talus and calcaneus while allowing normal motion and alignment. In a preferred embodiment, the implant is composed of a titanium alloy that is a combination of a cylindrical portion and an axially connected conical portion. The cylindrical portion has a surface with multiple parallel grooves that are each parallel to the transverse axis of the cylinder. The grooves are uniquely shaped with a perpendicular medial side and an angled lateral side. The implant is cannulated to enable use of a guide wire that insures proper alignment during insertion.

Abstract: A valve holder for delivering a prosthetic heart valve to an implant site is in various embodiments configured to reduce or eliminate the occurrence of suture looping or other damage to the prosthetic valve during implantation. The valve holder can be configured to deploy or actuate automatically when performing preparatory steps that are already familiar to practitioners, such as attaching a delivery handle to the valve holder, so that the valve holders will not require additional steps or training to use. Therefore, operation of the valve holders is kept simple, and occurrences of mistakes caused by user error can be minimized or reduced. Valve holders according to different embodiments can be designed to accommodate implantation of prosthetic heart valves from either the inflow end or the outflow end of the native valve annulus.

Abstract: A method of assembling a pivotal bone anchor assembly includes positioning a capture portion of a shank, a retainer, and an insert into a receiver. The receiver includes an internal cavity with a circumferential groove adjacent a bottom opening, a first channel with a discontinuous downward-facing surface below a guide and advancement structure, and an internal cylindrical surface with a fixed rotation abutment surface. The shank with a capture portion is uploadable through the bottom opening. The retainer is uploadable into the circumferential groove to engage and hold the capture portion within the cavity. The insert includes a cylindrical body with a second channel between upstanding arms and is positionable into the first channel with the second channel transverse to the first channel. The method further includes rotating the insert within the receiver until the second channel of the insert is aligned with the first channel of the receiver.

Abstract: A method of delivering and deploying a modular heart valve prosthesis includes delivering a first heart valve device including a first valve support and an anchoring frame in a radially compressed configuration to a site of a native heart valve. A first prosthetic valve including first leaflets having a first thickness is disposed within the first valve support. The method further includes deploying the first heart valve device within native leaflets of the native heart valve, delivering a second heart valve device in a radially compressed configuration to within the first valve support, and deploying the second heart valve device within the first prosthetic valve and the first valve support. The second heart valve device includes a second valve support and a second prosthetic valve comprising second leaflets having a second thickness greater than the first thickness disposed within the second valve support.

Abstract: A prosthetic heart valve and delivery device for delivering the prosthetic heart valve to a target implantation site, which reduce contact between the prosthetic heart valve and a delivery sheath through which the delivery device is advanced to the target implantation site, is disclosed. As one example, a prosthetic heart valve may comprise a frame including a first end with a plurality of apices spaced apart from one another around a circumference of the first end and a cover element covering the plurality of apices. The cover element may include a cushioning element or a bio-resorbable element.

Abstract: An implantable prosthetic device can include a radially expandable and compressible frame including an inflow end portion and an outflow end portion. The frame including a plurality of struts, and at least one expansion and locking mechanism having a first member, a second member extending at least partially into the first member, and a third member. The third member can include an engagement portion. The plurality of struts can include a first strut and a second strut pivotably coupled to one another to form an apex, the first strut having a first flange and the second strut having a second flange. When the frame is expanded, distal advancement of the third member can position the engagement member between the first and second flanges such that they engage the engagement member to resist pivoting of the first and second struts relative to one another to resist compression of the frame.

Abstract: A knee gap tensioning apparatus includes: a baseplate, a top plate, and a linkage operable to move the top plate relative to the bottom plate between retracted and extended positions, the linkage including: a first toggle linkage, including a lower link and an upper link; a second toggle linkage, including a lower link and an upper link; a connector linkage interconnecting the first and second toggle linkages; wherein the links comprise parallel pivot axes and the linkage is configured so as to produce linear movement of the top plate relative to the base plate, in response to a rotational movement of one or more of the links; and wherein the linkage includes an input shaft coupled to the linkage and configured to accept a rotary input about an axis parallel to the parallel pivot axes of the links of the linkage.

Abstract: An orthopaedic joint replacement system is shown and described. The system includes a number of prosthetic components configured to be implanted into a patient's knee. The system also includes a number of surgical instruments configured for use in preparing the bones of the patient's knee to receive the implants. A number of methods for using the surgical instruments to prepare the bones is also disclosed.

Abstract: A stent delivery system can include a core assembly sized for insertion into a corporeal lumen and configured for advancing a stent toward a treatment location in the corporeal lumen. The core assembly can include a proximal restraint having a bumper section, a distal section distal to the bumper section, a lumen extending through the bumper and distal sections, and an undercut section including a recess at least partially surrounding the lumen. The recess can abut and/or be formed in the bumper and/or distal sections.