Abstract: The invention provides a recombinant keratinocyte having nucleic acid encoding a human &bgr;3 integrin subunit introduced therein. This recombinant keratinocyte is able to adhere to fibrin/fibrinogen, and therefore when used in a graft procedure the recombinant keratinocyte is able to adhere to fibrin/fibrinogen present in any fibrin clot in the wound. The invention thus further provides a method of enhancing wound healing in a graft procedure by using the recombinant keratinocytes.
Type:
Grant
Filed:
April 13, 1999
Date of Patent:
July 31, 2001
Assignee:
The Research Foundation of State University of New
York