Abstract: A method of generating a visual representation of a complex medical diagnosis includes receiving a first signal corresponding to a measurement of a patient biological condition. A second signal corresponding to a measurement of a patient performance condition is also received. The first and second signals are processed and a visual representation of a diagnostic assessment is generated. The diagnostic assessment is based at least in part on the patient biological condition and the patient performance condition. The visual representation is marked with the measurement of the patient biological condition and the measurement of the patient performance condition.

Abstract: An image processing unit includes a grayscale image creating unit, a shininess region removal unit, a region of interest tracing unit, and a time intensity curve measuring unit. The time intensity curve measuring unit includes a pixel value measuring unit which measures the pixel value of a specific point in the fluorescence image photographed by the fluorescence image pickup element, and a measurement position movement unit which moves the measurement position of the pixel value in the pixel value measuring unit in accordance with the region of interest traced by the region of interest tracing unit.

Abstract: A system and method for confirming placement of a biopsy tool in a target including a navigation component to track the position of a catheter navigated into a luminal network, and a catheter configured to receive a biopsy tool. The system and method receive a first plurality of fluoroscopic images, generate a first fluoroscopic three-dimensional reconstruction from the plurality of fluoroscopic images, and present a first slice of the 3D reconstruction depicting the catheter in relation to a target visible in the slice of the 3D reconstruction.

Abstract: Systems, methods, and apparatuses for conducting heat from an ultrasound transducer and reducing drop impact forces are disclosed. A thermal management system including a thermally conductive compliant component in an ultrasound probe is disclosed. The thermal management system may include thermally conductive compliant component coupled to a transducer assembly. A printed circuit assembly (PCA) may be coupled to the compliant component. The thermally compliant component may conduct heat from the transducer assembly to the PCA. The PCA may be further coupled to a cable that may conduct heat from the PCA and away from the ultrasound probe.

Abstract: The present invention describes a new functional biomarker of vascular inflammation and its use in predicting all-cause or cardiac mortality. The invention also provides a method for stratifying patients according to their risk of all-cause or cardiac mortality using data gathered from a computer tomography scans of a blood vessel to determine a specific combination of structural and functional biomarkers of vascular inflammation and disease.

Abstract: An apparatus for use in a magnetic resonance (MR) system for capturing an MR Elastography measurement of a biological lifeform may include a platform; a gel pad on a surface of the platform; and a sensor array. In some embodiments, the sensor array includes at least one ultrasound transducer, and at least one radiofrequency (RF) transmitter and receiver coil. The sensor array is at least partially embedded within the gel pad, and the gel pad is configured to provide mechanical impedance matching between the at least one ultrasound transducer and the biological lifeform. In some embodiments, a system includes the apparatus and an MR system, the MR system including an ultrasonic wave generator, an interface circuit, and a computing device. In some such embodiments, the ultrasonic wave generator is configured to generate one or more shear waves in the biological lifeform.

Abstract: The invention relates to a device (1) for endoscopic optoacoustic imaging comprising an imaging unit (2) configured to be at least partially inserted into an object (5), said imaging unit (2) comprising an irradiation unit (6) configured to irradiate a region of interest (7) inside the object (5) with electromagnetic radiation and a detection unit (8) comprising at least one ultrasound transducer configured to detect ultrasound waves generated in the region of interest (7) in response to irradiating the region of interest (7) with the electromagnetic radiation and to generate according detection signals, wherein the at least one ultrasound transducer exhibits a field of view (8b) being at least partially located in the irradiated region of interest (7).

Abstract: Apparatuses, capacitor arrays, and methods for generating therapeutic compressed acoustic waves (e.g., shock waves). In the apparatuses and at least some of the methods, a plurality of electrodes can disposed in a chamber that is defined by a housing and configured to be filled with liquid, and a plurality of capacitors can be electrically connected to the electrodes and can be carried by (e.g., physically coupled to) the housing. Voltage pulses can be applied simultaneously to the plurality of electrodes (e.g., to begin to vaporize and ionize portions of the liquid to provide at least one inter-electrode conductive path between the plurality of electrodes) and to the capacitors to charge the plurality of capacitors). The plurality of capacitors can be configured to, upon reaching a threshold charge, discharge to the plurality of electrodes (e.g.

Abstract: Disclosed is a system for detecting an internal object in a body. The system includes at least one antenna pair including two antennas which are adapted to be symmetrically positioned around the body in relation to a line of symmetry. The system is adapted to transmit microwave signal into the body which are reflected and/or scattered from the internal object. The system is adapted to receive the reflected and/or scattered microwave signals, and to compare the received microwave signals at the symmetrically positioned antennas. The system is adapted to detect the internal object or a change in an already detected internal object when there is a difference between the received microwave signals at symmetric antenna pairs. The difference is related to the different dielectric properties between the internal object and the body.

Abstract: A method, device and system for ultrasonic delivery and attachment of ligand-receptor based drugs and/or drug carriers and/or image enhancing contrast agents utilizing catch and slip bond mechanisms in a targeted part(s) of the human or animal (patient) body or organs or tissue is described and disclosed. The system includes an acoustic power source coupled to an acoustic transducer with the acoustic transducer placed upon a patient's delivery zone. The acoustic transducer transmits an acoustic field to the target drug delivery and/or imaging zone. A detection probe and/or a probe of an imaging system are placed over or within said delivery zone and the probe is coupled to a sensing/imaging system. A control computer that controls power and wave shape of the acoustic signal generated into the acoustic filed by the acoustic power source and receives data from the sensing/imaging system.

Abstract: A marker system includes a biopsy apparatus having a cannula and a stylet. The cannula has a distal end, the stylet has a distal stylet tip, and the stylet is received in the cannula. A tissue marker is coupled to the distal stylet tip. The tissue marker is configured to be contacted by the distal end of the cannula. The tissue marker is detached from the stylet distal tip by either of a proximal movement of the stylet relative to the cannula or a distal movement of the cannula relative to the stylet.

Abstract: Eyelid illumination systems and methods for imaging meibomian glands for meibomian gland analysis are disclosed. In one embodiment, a patient's eyelid is IR trans-illuminated with an infrared (IR) light. A trans-illumination image of the patient's eyelid is captured, showing meibomian glands in dark outlined areas, whereas non-gland material is shown in light areas. This provides a high contrast image of the meibomian glands that is X-ray-like. The lid trans-illumination image of the meibomian glands can be analyzed to determine to diagnose the meibomian glands in the patient's eyelid. The eyelid may be trans-illuminated by a lid-flipping device configured to grasp and flip the eyelid for imaging the interior surface of the eyelid. Also, an IR surface meibography image of the meibomian glands may also be captured and combined with the trans-illumination image of the meibomian glands to provide a higher contrast image of the meibomian glands.

Abstract: In a method and apparatus for acquiring and reconstructing a four-dimensional dynamic magnetic resonance (MR) image data record, MR data are continuously acquired by radial scanning of an examination region along radial k-space lines, and a dynamic region of the examination region, in which said dynamic procedure is relevant, is determined, as well as a non-dynamic region, which is not relevant to the dynamic procedure. Static image data are reconstructed from all of the acquired MR data, and image data therein originating from the non-dynamic region are marked and are then not used for reconstructing a dynamic image data record for the dynamic region.

Abstract: Certain aspects relate to a medical system that includes a robotically controllable field generator and an instrument guide. The instrument guide may guide a percutaneously insertable instrument along an insertion axis. The instrument guide may also be positioned on an electromagnetic (EM) field generator, where the EM field generator can generate an EM field. A first robotic arm may be coupled to the EM field generator and it may move the EM field generator and the instrument guide. The system then determines: an EM target positioned within a patient, and a registration that maps positions within an EM coordinate frame associated with the EM field to positions within a robotic coordinate frame. The system may also determine, based on the registration, a position of the EM target within the robotic coordinate frame. Based on the position of the EM target within the robotic coordinate frame, move the first robotic arm may move to align the insertion axis of the instrument guide with the EM target.

Abstract: Methods, devices, and systems are disclosed for affixing and orienting an ultrasound transducer to a patient. A mount has a base, with a top surface, a bottom surface, an outer surface, and a plurality of internal surfaces. Some of the internal surfaces define a number of through holes that pass through the top surface and the bottom surface at the periphery or outer edge of the base. A number of supports are also arranged on the outer surface of the housing to affix the mount to the patient, to affix the transducer to the mount, or both. At least one of the plurality of internal surfaces defines a channel between the top and bottom surfaces proximal to a center of the mount, which receives a transducer and directs the transducer head toward the patient.

Abstract: A magnetic resonance imaging method is includes collecting spatially encoded data from a subject using an MRI system, and directly extracting a number of temporal basis functions using at least a first portion of the spatially encoded data. The method further includes, after directly extracting the number of temporal basis functions, iteratively calculating a number of coefficient images using the number of temporal basis functions and at least a second portion of the spatially encoded data. Finally, the method includes generating a 4D image based on the number of temporal basis functions and the number of coefficient images.

Abstract: A method for identifying brain-state dependent functional areas of unitary pooled activity (FAUPAs) using a statistical model that does not require a priori knowledge of the activity-induced ideal response signal time course is provided. A system for identifying a functional network in a brain of a living object includes a FAUPA identifier configured to identify FAUPAs by analyzing a plurality of images of the brain over a predetermined period. The plurality of images include a plurality of voxels, and the FAUPA identifier analyzes each voxel of the plurality of voxels in relation to one or more surrounding voxels of each voxel until each voxel of the plurality of voxels is evaluated. A brain network identification module configured to construct the functional network based on the identified FAUPAs that are functionally connected. A display module configured to display images of the brain depicting the FAUPAs included in the functional network.

Abstract: A portable vein viewer apparatus may be battery powered and hand-held to reveal patient vasculature information to aid in venipuncture processes. The apparatus comprises a first laser diode emitting infrared light, and a second laser diode emitting only visible wavelengths, wherein vasculature absorbs a portion of the infrared light causing reflection of a contrasted infrared image. A pair of silicon PIN photodiodes, responsive to the contrasted infrared image, causes transmission of a corresponding signal. The signal is processed through circuitry to amplify, sum, and filter the outputted signals, and with the use of an image processing algorithm, the contrasted image is projected onto the patient's skin surface using the second laser diode. Revealed information may comprise vein location, depth, diameter, and degree of certainty of vein locations. Projection of vein images may be a positive or a negative image. Venipuncture needles may be coated to provide visibility in projected images.

Abstract: Systems, methods and devices are described including a medical device subassembly including a magnetic feature. Systems include such a catheter adapter subassembly or needle subassembly or guidewire introducer subassembly and a wire including a magnetic feature, and relative movement of the catheter adapter subassembly or needle subassembly or guidewire introducer subassembly and the wire can be determined using an magnetometer.

Abstract: A method is provided for generating an ultrasound image of an anatomical region having a volume. First image low resolution image data is enhanced by adapting a 3D anatomical model to the image data to generate a second, greater, quantity of ultrasound image data in respect of the anatomical region. The enhanced volumetric information is then displayed. An anatomical model is thus used to complete partial image data thereby increasing the image resolution, so that a high resolution volumetric image can be displayed with a reduced image capture time.