Abstract: Provided are: method of producing a sulfur-containing proanthocyanidin oligomer by reducing the molecular weight of proanthocyanidin in plants so that they can be readily absorbed through the intestine of an organism; and a health food composition and a pharmaceutical composition which contain the resultant sulfur-containing proanthocyanidin oligomer as an active ingredient and which are useful for treating and preventing various lifestyle-related diseases and brain diseases caused by generation of active oxygen species as well as for preventing aging.

Abstract: The present invention provides a method for the preparation of a plant jelly in the form of a jelly-like product wherein selected phospholipids (for example, PC, PE and lyso-PC/PE) play an important role in jellifying the mixture. The plant jelly has a plant hard fat blend and an oil blend in which the plant hard fat blend is made up of about 10-20% of a fat with a melting point of 30-40° C. and about 4-10% of a vegetable fat, and in which the oil blend is made up of about 1-3.5% phospholipids and about 70-80% liquid oil.

Abstract: The present invention relates to compositions comprising polypeptides and polysaccharides. The compositions are in general immune modulating. The invention also discloses methods of producing these compositions using filamentous fungi cultivated in liquid medium. The compositions are useful for example in the treatment of immune compromised conditions.

Abstract: The present invention relates to a composition containing an extract of pericapium zanthoxyli for protecting brain cells and improving memory, and the composition of this invention induces an effect of protecting brain cells for modern people under brain damage that is caused by environmental factors, such as various stresses, drinking and smoking habits, therefore, it can be used for medicines and health supplements inducing an effect of preventing, treating degenerative disorders and improving memory.

Abstract: The present invention relates to isolated bioactive compositions containing bioactive fractions derived from Theacea plants. The present invention also relates to bioactive topical formulations containing the bioactive compositions. The present invention further relates to methods of using the bioactive compositions of the present invention, including, for example, methods for inhibiting inflammatory activity in skin tissue of a mammal, for protecting skin tissue of a mammal from ultraviolet light-induced damage, and for normalizing skin disorders in skin tissue of a mammal. The present invention also relates to methods for isolating bioactive fractions derived from cell juice or a cell walls component a Theacea plant.

Abstract: Conjugates of Factor VII (FVII) and Factor VIIa (FVIIA) are provided, as are methods for preparing them. Methods for producing novel polypeptides contributing to the production of such conjugates are provided. Methods of treatment by administering a FVII or FVIIa conjugate are provided.

Abstract: The invention relates to a method for producing injectable medicament preparations containing a therapeutically and/or diagnostically effective substance which is comprised of an active agent, of a spacer molecule and of at least one protein-binding molecule. After being brought into contact with the body, said therapeutically and/or diagnostically effective substance covalently bonds to the body fluid constituents or tissue constituents via the protein-binding molecules, thus providing a form of transport of the active agent that can be hydrolytically or enzymatically cleaved, according to pH, in the body while releasing the active agent.

Abstract: The present invention features compositions and related methods for treating IBS and other gastrointestinal disorders and conditions (e.g., gastrointestinal motility disorders, functional gastrointestinal disorders, gastroesophageal reflux disease (GERD), duodenogastric reflux, Crohn's disease, ulcerative colitis, Inflammatory bowel disease, functional heartburn, dyspepsia (including functional dyspepsia or nonulcer dyspepsia), gastroparesis, chronic intestinal pseudo-obstruction (or colonic pseudo-obstruction), and disorders and conditions associated with constipation, e.g., constipation associated with use of opiate pain killers, post-surgical constipation (post-operative ileus), and constipation associated with neuropathic disorders as well as other conditions and disorders using peptides and other agents that activate the guanylate cyclase C (GC-C) receptor.

Abstract: Methods for synthesizing proinsulin polypeptides are described that include a contacting a proinsulin polypeptide including an insulin polypeptide coupled to one or more peptides by peptide bond(s) capable of being cleaved to yield the insulin polypeptide with an oligomer under conditions sufficient to couple the oligomer to the insulin polypeptide portion of the proinsulin polypeptide and provide a proinsulin polypeptide-oligomer conjugate, and cleaving the one or more peptides from the proinsulin polypeptide-oligomer conjugate to provide the insulin polypeptide-oligomer conjugate. Methods of synthesizing proinsulin polypeptide-oligomer conjugates are also described as are proinsulin polypeptide-oligomer conjugates. Methods of synthesizing C-peptide polypeptide-oligomer conjugates are also described.

Abstract: A composition for promoting lacrimal secretion which can be used safely and effectively in the lacrimal secretion promoting therapy, not in the conventional supplemental therapy of lacrimal fluid components is provided. The composition comprises a component which activates PAR-2. Also, a contact lens which retains and/or contains said composition for promoting lacrimal secretion is provided.

Abstract: An extract is made by cooking the fruit of an eggplant for about 15 to 30 minutes at about 120 to about 250° C., extracting the juice from the cooked fruit, and adding an oxidant to the juice that reacts with a component in it and changes its color from beige to black. Eggplants such as the Chinese eggplant and oxidants such as ferrous salts, such as ferrous sulfate, work particularly well. The extract can be formulated into various types of products, including pills, tablets, capsules, suppositories, foams, lotions, creams, and enema liquids. The products may be used for treating a variety of medical conditions, including gastrointestinal inflammation, hemorrhoids, skin inflammation, and other problems.

Abstract: Compositions of matter comprising purified aqueous extracts of medicinal plants which are prepared by a method employing the steps of, rinsing the plant with clean water, boiling the plant in a boiler, allowing steam to escape carrying toxins from the plant, and filtering the resulting aqueous extract to produce a clear, clarified solution of the extract which has significant anti-HIV activity.

Abstract: Disclosed are a facial pack composition and a bathing composition based on loess, and methods for preparing the same. The bathing composition makes a user feel refreshed, prevents arteriosclerosis and fat accumulation in human bodies, is useful for the treatment of maturating diseases such as dermatophytosis and dermatitis and stimulates metabolism and blood circulation system of the human body. Additionally, the facial pack includes loess having a fine particle size sufficient to avoid skin irritation and thus does not adversely affect the skin even if the user uses the pack everyday. The loess is pretreated by a unique aging method and selected additives, so that the far infrared ray-emitting effect of the loess can be maximized. Therefore, it provides skin health-aid and cosmetic effects.

Abstract: The present invention comprises a pain balm comprising a fermentation extract of the cultivar of the genus capsicum.

Abstract: A skin treatment composition, comprising an effective combination of ingredients selected from cumin, cloves, peach kernel, olibanum, eagle wood, giant hyssop, almond, and pachira macracarpa is provided. The composition can be used as a skin cleanser, as a deodorant, and to treat a wide array of skin problems, including signs of aging, such as wrinkles, and skin sagging, dark spots, skin infections, skin irritation, cuts, scarring, acne, cold sores, chapped lips, and varicose veins.

Abstract: A composition for providing aromatherapy, and in particular, symptomatic relief of nasal and sinus congestion is provided in unit dosage format. The composition includes a penetrating aromatic vapor whose release from a preparation of warm water is augmented by an effervescent component which reacts in the warm water to promote release of the aromatic fragrance, or sustained over time by tableting or gelatin encapsulation. As the fragrance is inhaled, symptomatic relief is obtained. The composition of matter may be rendered ingestible, so that the warm water containing the composition is consumed following inhalation. In preferred embodiments, the release of the penetrating aromatic fragrance persists over time.

Abstract: The invention herein describes a procedure for organically extracting the lipophilic components from plants of the Family Euphorbaciae, specifically but not limited to the genus Croton. The extraction (CGO 110), is deplete of the normal proanthocyanidin content found in the parent material, yet retains its pharmacocological abilities and unlike the parent material, is selectively cytotoxic to cancer cells. The depletion of the proanthocyanidin components makes the product more amenable to preparations for the benefit of ameliorating both human and animal disease.

Abstract: A method of making an implantable scaffold for repairing damaged or diseased tissue includes the step of suspending pieces of an extracellular matrix material in a liquid. The extracellular matrix material and the liquid are formed into a mass. The liquid is subsequently driven off so as to form interstices in the mass. The scaffold may further comprise biological agents that promote tissue repair and healing. Porous implantable scaffolds fabricated by such a method are also disclosed.

Abstract: Compositions and methods of inhibiting tumor cell growth and treating and preventing cancer are provided based on administration of an orange peel extract either alone or in combination with other phytochemicals.

Abstract: The present invention describes a composition for preventing pruritis or inflammation that includes field pussy-toes plant extract, and methods of using and manufacturing the same. The compositions of this invention have been found to be especially useful in preventing and treating lesions from poison ivy, chicken pox, and cold sores.