Abstract: An antibody variable region of a monoclonal antibody specifically binding to human tumor necrosis factor-? contains at least one of a heavy chain variable region and a light chain variable region having specific complementarity determining regions therein. A nucleic acid molecule encoding the same, a recombinant vector containing the nucleic acid molecule, and a cell transformed with the recombinant vector are also provided.
Type:
Grant
Filed:
November 16, 2004
Date of Patent:
September 19, 2006
Assignee:
Yuhan Corporation
Inventors:
Heui Il Kang, In Young Ko, Moo Young Song, Chang Seok Kim, Sang Koo Park, Jae Sun Lee, Tae Hyoung Yoo, Kang In Na