Patents Examined by Clark Petersen
  • Use of MDCK cell line to predict corneal penetration of drugs
    Patent number: 7297505
    Abstract: A new method of evaluating the ability of drug molecules to penetrate the cornea is described. The permeation rate of the drug molecules in MDCK cells is utilized to predict the ability of the molecules to penetrate the cornea. The method is useful for in vitro screening of potential new ophthalmic drugs, as well as in the design of new drug molecules for topical ocular administration.
    Type: Grant
    Filed: April 25, 2005
    Date of Patent: November 20, 2007
    Assignee: Alcon, Inc.
    Inventors: Andrew Rusinko, Mark R. Hellberg, Jesse Albert May, Geoffrey Robert Owen