Abstract: A delivery device for an annular implant that includes a balloon expansion mechanism and an annular implant having an adjustable dimension. The balloon expansion mechanism includes an inflation tube attached to a non-occluding balloon collar which is supported by trusses radially extending from a trocar. The annular implant further includes a flexible ring core, contiguous coiled spacers, and anchoring blocks. The flexible ring core is adjusted via a cinching mechanism. The anchoring blocks are spaced along the ring core by the contiguous coiled spacers, which keeps the distance between each pair of anchoring blocks equidistant as the ring core diameter is manipulated by the device user. The annular implant can also include gunbarrel elements housed in the trocar. Each gunbarrel element contains a gunbarrel pusher which drives an attachment element into the annular implant and annular tissue.

Abstract: A method and apparatus for sealing a puncture or incision formed percutaneously in a tissue. The apparatus including an anchor, a sealing plug, a filament connected between the sealing plug and the anchor, a compaction member assembly, a spool and a driving plate. The compaction member assembly being disposed adjacent the sealing plug and structured and arranged to apply an axially directed compressive force to automatically compact the sealing plug toward the anchor. The spool has a portion of the filament wound thereon. The driving plate being connected to the spool and having a cam surface portion. The cam surface portion is arranged to contact a proximal end of the compaction member assembly upon rotation of the spool to advance a distal end of the compaction member assembly.

Abstract: The present invention is directed to tissue closure devices for closing a tissue opening, including one or more closure components, each closure component having a first member and a second member, each of the first and second members having a first surface that adheres to a tissue surface proximate to the tissue opening, each of the first and second members having a second surface substantially orthogonal to the first surface, and each of the first and second members having a transitional region between the first surface and the second surface which is contoured to evert an edge of the tissue opening upon the drawing together of the first and second members. The present invention is also directed to systems and kits, dressing systems, and methods for tissue repair and closure.

Abstract: A haptics system for retaining an accommodating intraocular lens (AIOL) in a human eye has an anterior surface and a posterior surface, and at least one shape memory optical element resiliently elastically deformable between a natural shape with a first Diopter strength and a deformed shape with a second Diopter strength different than the first Diopter strength whereby the AIOL has a continuously variable Diopter strength between a minimum Diopter strength for distance vision purposes and a maximum Diopter strength for near vision purposes.

Abstract: A system and method for sharing and absorbing energy between body parts. In one particular aspect, the system is an unlinked structure which facilitates absorbing energy between members forming a joint such as between articulating bones.

Abstract: Medical devices and methods are provided for forming an intestinal bypass anastomosis, such as for treatment of obesity. The medical devices and methods are minimally invasive and reduce complications. Two magnet assemblies are deployed in a spaced apart relationship, and are transluminally brought together to approximate the tissue and form an anastomosis therebetween.

Abstract: A method for performing a coronary artery bypass graft procedure on a patient to connect a bypass vessel to a target vessel includes the steps of creating an opening in the patient that communicates with the thoracic cavity of the patient; providing a bypass vessel having a lumen and at least one free end; passing the free end of the bypass vessel from the thoracic cavity through the opening to a position outside the body of the patient; attaching a connector to the free end of bypass vessel while the free end of the bypass vessel is outside the body of the patient; passing the free end of the bypass vessel from the position outside the body of the patient through the opening and into the thoracic cavity; and connecting the free end of the bypass vessel to a target vessel with the connector.

Abstract: Articulation joints for use in connection with a surgical instrument that has a portion that must be passed through a trocar or similar structure and then articulated relative to another portion of the instrument received within the trocar. Various embodiments of the articulation joint include at least one flexible driven member to articulate the surgical implement relative to the handle assembly of the instrument.

Abstract: A medical device for wound closure, including an elongate body with a plurality of portions and a perforated region disposed therebetween. The medical device may also include an alignment member. The wound plug may also have a first position for insertion, the portions being mechanically coupled to each other, and a second position where one or more of the portions are spatially separated.

Abstract: A suturing assembly is provided that is configured to pull a capsule attached to a suture through tissue. The suturing assembly includes a shaft aligned on a longitudinal axis of the suturing assembly, and a head coupled to the shaft. The head includes a proximal portion and a distal end spaced apart from the proximal portion by a throat. The proximal portion houses a needle that is movable through a needle exit port. The proximal portion of the head and the needle exit port are both aligned on the longitudinal axis. A proximal side of the distal end of the head defines a cavity adapted to receive the capsule and a distal side of the distal end of the head defines a slot adapted to allow the suture to pass through the distal end of the head and into the cavity.

Abstract: There are disclosed various embodiments of surgical tacks for use in surgical procedures. The tacks generally include a head and a barrel portion extending distally from the head. Preferably, the head and the barrel portion define a throughbore for receipt of a drive instrument. A thread on the head is provided to engage threads in the installation tool. A tissue thread is provided on the barrel portion to engage tissue. Distal and proximal surfaces of the tissue thread may be oriented at various angles relative to the barrel portion. There is also disclosed an insertion instrument to insert one or more tacks as well as a method of use. There is further disclosed a model device for use in explaining the operation of the instrument.

Abstract: Systems, devices and methods for securing tissue including the annulus of a mitral valve. The systems, devices and methods may employ catheter based techniques and devices to plicate tissue and perform an annuloplasty.

Abstract: A prosthesis for implantation at a native semilunar valve includes a prosthetic distal valve, which includes a pliant material configured to collapse inwardly towards a longitudinal axis of the prosthesis during diastole, and to open outwardly during systole, and a distal fixation member configured to be positioned in a downstream artery of the subject. The apparatus also includes a proximal fixation member coupled to the distal fixation member, and configured to be positioned at least partially on a ventricular side of the native semilunar valve. The proximal fixation member is shaped so as to define a lattice that is shaped so as to define an intermediary portion that is coupled to the pliant material of the valve and diverges outwardly from the longitudinal axis, and a distal portion that is distal to the intermediary portion and diverges outwardly from the intermediary portion of the lattice. Other embodiments are also described.

Abstract: A flexible member securing assembly to secure a flexible member relative to tissue is provided and includes a shaft, an arm, an anchor, and a flexible member grasper. The shaft extends along a longitudinal axis from a first end and a second end. The arm is extendable from the shaft second end and the flexible member grasper is adjacent to a distal end of the arm to position the flexible member in relation to the anchor. The anchor is removably positioned at the shaft second end and can retain the flexible member in the tissue. Methods of securing a flexible member are also provided.

Abstract: A method and apparatus for coupling a soft tissue implant into a locking cavity formed within a bone is disclosed. The apparatus includes a member to pull the soft tissue implant into a femoral tunnel. The member includes a suture having first and second ends which are passed through first and second openings associated with the longitudinal passage to form a pair of loops. A collapsible tube is positioned about the suture. Application of tension onto the suture construction causes retraction of the soft tissue implant into the femoral tunnel and the collapse of the tube to form an anchor.

Abstract: The present disclosure is directed to a fastener applying surgical fastener applier for ensuring proper seating of a fastener within tissue. The surgical fastener applier includes an actuation mechanism, a drive mechanism, and a control system. The control system is configured to determine loading along an axis and to allow movement of the drive mechanism.

Abstract: A barbed suture includes a flexible thread having a core with a leading end, a trailing end, and a central axis. The barbed suture includes a first flexible flap connected to the core, the first flap extending between the leading and trailing ends of the core, and a second flexible flap connected to the core, the second flap extending between the leading and trailing ends of the core. The flexible flaps and the core have an S-shaped profile when viewed in cross-section. The barbed suture includes first and second slots formed in the respective first and second flaps for dividing the flaps into first and second barbs projecting from the core, whereby each slot extends outwardly from the core and rearwardly toward the trailing end of the core.

Abstract: Assemblies, devices and methods are provided for suture management associated with surgical procedures for anchoring suture to bone. Suture elements mounted to suture anchors are terminated in suture loops or tags, and associated stop members that in combination with visual coding provide suture identification, prevent accidental unmounting of suture from suture anchors, and reduce the number of suture legs requiring active management during complex arthroscopic repairs. The present invention also provides exemplary drivers that can be used with the various methods and devices disclosed herein, or with other methods and devices known in the art.

Abstract: A device for loading a surgical knotting element on an applicator tool. One embodiment of the device includes a channel dimensioned to receive an applicator tool comprising a coupling. A surgical knotting element comprises a coupling complementary to the coupling of an applicator tool and a suture path. A carriage receives the surgical knotting element. The carriage is moveable in a transverse direction relative the channel between a first position where the knotting element is misaligned with the channel and a second position where the couplings are engaged with one another.

Abstract: A hemostasis assembly having a selectively expandable hemostasis member can be used with a medical device and in a method for delivering a closure element through tissue and into an opening formed in, or adjacent to, a wall of a blood vessel or other body lumen of any size while maintaining or improving hemostasis. The medical device and method of use utilizes such an expandable hemostasis member to maintain or improve hemostasis throughout a medical procedure for closing and/or sealing openings through tissues and/or blood vessels.