Abstract: Ambulatory infusion pumps, cannula insertion mechanisms, and medicament sealing assemblies, including cannula seal assemblies, plus related components, as well as component combinations and related methods.

Abstract: Balloon catheter includes an outer shaft having a hypotube and a monolithic single-layer distal outer member, a balloon in fluid communication with an inflation lumen, and a monolithic inner tubular member having a guidewire lumen defined therethrough. The outer shaft has the inflation lumen defined therethrough. The monolithic single-layer distal outer member is necked to a reduced diameter along an entire length thereof. A proximal end of the monolithic single-layer distal outer member is coupled to the hypotube. A distal section of the hypotube comprises a skive defined by a first angled cut, an axial cut, and a second angled cut. The balloon has a proximal balloon shaft coupled to a distal end of the monolithic single-layer distal outer member. The monolithic inner tubular member extends distally from a proximal port in the monolithic single-layer distal outer member through the balloon to form a tip.

Abstract: A dosage measurement system is adapted to receive a motion from a dosage injection mechanism disposed within a drug injection pen. The dosage measurement system includes a substrate, a sensing capacitor disposed on the substrate, and a lifting tab. The sensing capacitor includes a dielectric layer disposed between a base plate and an adjustable plate. The lifting tab is attached to the adjustable plate and positioned to engage an undulation pattern disposed on a component attached to the dosage injection mechanism. The lifting tab is adapted to physically change a separation distance between the adjustable plate and the base plate in a reciprocal manner in response to the motion of the dosage injection mechanism and engagement with the undulation pattern. A capacitance of the sensing capacitor changes in response to the engagement of the lifting tab with the undulation pattern and the motion of the dosage injection mechanism.

Abstract: A surgical apparatus for delivering fluid to treat renal hypertension including an elongated member having a distal tip and a plurality of openings formed in a sidewall proximal of the distal tip. A plurality of fluid delivery members are movably positioned in the elongated member, each of the fluid delivery members having a lumen and at least one opening communicating with the lumen for delivering fluid extravascularly. An actuator is operatively associated with the fluid delivery members, the actuator actuable to a first position to move the fluid delivery members from a retracted position within the elongated member to a deployed position extending radially with respect to the elongated member. A balloon is expandable radially from the elongated member to seal the renal artery during application of fluid through the fluid delivery members.

Abstract: Skin can be treated by piercing skin with a plurality of needles of an injection device and ejecting a dose of fluid therethrough. The device can include a housing, a plunger disposed in the housing, a cartridge disposed in the housing, and one or more dosing chambers. The plurality of needles can be coupled to the housing and be in fluid communication with the cartridge. Advancement of the plunger can cause a dose of fluid to be ejected from the plurality of needles.

Abstract: A medical device for use with an associated tube inserted into an incision formed in skin or tissue of a patient includes a dressing including an opening sized to receive and allow movement of the associated tube. A valve is operatively connected with the opening of the dressing and includes a main body; and an opening formed in a portion of the main body. The opening is sized and dimensioned to accommodate the surgical tube.

Abstract: A portable pen-type drug injection device (300) comprises a main portion (301) and a clip (360). The clip comprises a base portion mounted to a portion of the drug delivery device, and a clip gripping portion with a free end. The device further comprises drug expelling means having dose setting means (340) allowing a user to set a dose of drug to be expelled, and a piston rod adapted to move a piston of a loaded cartridge in a distal direction to thereby expel drug from the cartridge. Electronic circuitry comprises sensor means adapted to detect a set and/or an expelled dose, and a display (374) is provided to display dose-related values, wherein at least a portion of the display is arranged in the flexible clip main portion.

Abstract: A bicanalicular probe intended to be inserted into the nasolacrimal duct of a patient including a central tubular part 1 made from a material compatible with insertion into the human body, preferably silicone, and two termination parts 4, 5 each fixed to one end of the central tubular part 1, characterized in that the two thickened parts 6, 7 project from the central tubular part, the two thickened parts being firstly at a distance from each other and secondly each at a distance from the ends 2, 3 where the termination parts are attached.

Abstract: Auto-injectors and associated assemblies and methods for delivery of medicament in a controlled manner are disclosed herein.

Abstract: Intraluminal and endovascular devices and methods of manufacturing intraluminal and endovascular devices may be provided. In one implementation, an intraluminal device may include a sheath having a flexible distal bending segment and a core wire arranged within the sheath. The core wire may include a distal end portion doubled back in a loop within the sheath such that the distal tip of the core wire is situated proximally from the loop. The intraluminal device may also include a movement restrictor within the sheath that is configured to limit axial movement of the distal tip of the core wire. Limiting the axial movement of the core wire distal tip may cause the loop of the core wire to buckle, resulting in a bend in the distal bending segment of the sheath, when a force is exerted on the core wire.

Abstract: An Infusion device (1) for administering a medical fluid to a patient, comprises: a housing (10); a receptacle (11) arranged on the housing (10) for receiving a syringe (2); a pusher device (12) movable in a pushing direction (P) for acting onto a piston (21) of a syringe (2) received on the receptacle (11); a drive element (13) connected to the pusher device (12), the drive element (13) being longitudinally movable relative to the housing (10) for moving the pusher device (12) along the pushing direction (P); a driving rod (14) having a screw thread (140) and being rotatable about a rotational axis (R1); an electric drive device (141) for rotating the driving rod (14); a clutching device (130) connected to the drive element (13) and being actuatable, by an actuation device (15), to engage, in a clutched state, with the screw thread (140) of the driving rod (14) for translating a rotational movement of the driving rod (14) into a longitudinal movement of the drive element (13) along the driving rod (14), and

Abstract: A connector for facilitating the connection of one piece of tubing to another so that fluid can flow from one piece to the other in a sterile manner. Characteristics of the connector include, but are not limited to, a flange at one of the connector, the flange comprising a recess for storage of at least part of a protective shield which Is removable after the flange is connected to the flange of a second connector.

Abstract: A neurosurgical apparatus includes a guide device and a neurosurgical instrument is disclosed. The guide device includes a tube for insertion into the brain and a head attached to the proximal end of the tube for affixing the guide device to a hole formed in the skull. The head has a passageway therethrough in communication with the bore of the tube such that the bore of the tube and the passageway through the head define an internal channel through which a neurosurgical instrument can be passed into the brain of the subject. The neurosurgical instrument is for insertion to a desired brain target through the internal channel of the guide device. The apparatus includes one or more sealing elements for providing a fluid tight seal between the internal channel of the guide device and the exterior of the neurosurgical instrument to prevent fluid leakage from guide tube.

Abstract: A concealable feeding tube assembly includes a tube and a removable member. The tube has an insertion portion and a feeding portion respectively at two ends thereof. The feeding portion is configured for insertion into a nasal cavity of a patient and intercommunicates with the insertion portion. The removable member is detachably attached to the tube and is configured to seal the feeding portion. The removable member includes an abutment portion extending beyond a lateral face of the removable member.

Abstract: A medical insertion device includes an introducer assembly, a needle, and a housing. The introducer assembly includes a dilator coaxially disposed in a sheath, the dilator removably engaged to the sheath in an insertion configuration. The needle is coaxially disposed in the dilator, the needle having a distal tip and a proximal end coupled to a needle hub. The housing may be removably engaged to the dilator. The needle hub is movably disposed in the housing between a first locked position, in which the distal tip of the needle extends a first length from a distal end of the dilator, a second locked position, in which the distal tip of the needle extends a second length from the distal end of the dilator less than the first length, and a third locked position, in which the distal tip of the needle is within the dilator.

Abstract: A foam transfer or dispensing device is described which dispenses foam from a source of foam, typically a pressurised canister, and which enables efficient purging or air and an initial volume of foam from the device to ensure foam sterility and quality when a syringe is filled from the device. The device comprises a foam inlet arranged for communication with a source of foam, a foam pathway in fluid communication with the foam inlet and comprising a foam outlet, arranged for engagement by a syringe nozzle; and a waste outlet in fluid communication with the foam pathway. The foam pathway comprises a tubular projection arranged to extend through the foam outlet and into a syringe nozzle when a syringe is connected to the foam outlet, which improves the efficiency of the purging process and prevents pooling of air or foam. The device further comprises a means for restricting displacement of material through the waste outlet, so that the user can control the volume of foam that is wasted.

Abstract: Deflectable apparatus and methods for performing a procedure within a patient's body using such apparatus are provided. Generally, the apparatus includes an elongate tubular member including a proximal end, a distal end, a longitudinal axis extending between the proximal and distal ends, a deflectable distal portion including first and second lumens spaced apart from one another on generally opposite sides of the longitudinal axis, and a handle coupled to the proximal end of the tubular member. A pull wire includes a loop disposed within the handle and first and second segments extending from the loop and slidably received in the first and second lumens, respectively, and coupled to the distal end. An actuator is provided on the handle for applying tension to either the first or the second segment to cause a distal portion of the tubular member to deflect, e.g., in opposite directions.

Abstract: A medication delivery device for treatment of a pulmonary disorder in a patient includes an elongate member, an expandable member is coupled to a distal end of the elongate member, and an agent delivery portion coupled to an external surface of the expandable member. The agent delivery portion includes an agent that disrupts nerve activity.

Abstract: An apparatus for determining at least one of the peritoneal pressure in the abdomen of a patient, and the drainage state of the abdomen of a patient, includes at least one pump for conveying a dialysis solution into the abdomen, and at least one measurement device for measuring the pressure in the dialysis solution. The apparatus has at least one control unit configured to control the pump and the measurement device such that a first measurement of the pressure is carried out by the measurement device with a stationary pump to obtain a first measured pressure value. The pump subsequently operates to convey a partial volume of the total inflow volume of the dialysis solution into the abdomen. The pump then stops, and a second measurement of the pressure is carried out by the measurement device to obtain a second measured pressure value.

Abstract: A smart plunger rod adapted to push a medication out of a syringe is disclosed. The plunger rod comprises a shaft sized and dimensioned to act on a piston on the syringe and a finger actuated head portion containing at least two subunits of a wireless sensor. In a pre-activation configuration, the subunits are spaced apart from each other by a physical barrier and the wireless sensor is non-operational. In a post-activation configuration, the subunits are connected to each other and the sensor is operational to send a signal. A user activates the finger actuated head portion to reversibly move the physical barrier and moves the plunger rod from the pre-activation configuration to the post-activation configuration. The signal sent by the sensor comprises information relating to ejecting the medication out of the syringe, and is received by a remote receiver.