Abstract: The invention relates to inhibitory compounds of a p38 MAP kinase having a structure of type (I)-(VII) which can be used for the treatment or prophylaxis of adhesion. Pharmaceutical compositions are disclosed containing an effective amount of the substance SB203580 or one or more of the conjugated compounds of type (I)-(VII) or a combination thereof, and a pharmaceutically acceptable carrier, a diluent or an excipient. Also disclosed is the use of the substance SB203580 as an agent having anti-adhesion activity. Also disclosed is a method for the prophylaxis and/or treatment of a disease or a condition in which there is a possibility of the formation and/or growth of adhesions, which makes it possible to dispense with the additional administration of a preparation in the post-operative period.
Abstract: The present invention is directed to pesticidal mixtures comprising sabadilla oil and at least one fungicide and methods of controlling pests including pathogenic fungi by application of pesticidal mixtures comprising sabadilla oil and at least one fungicide.
Abstract: The present invention relates to an improved plant growth regulation composition comprising a plant growth regulator and a surfactant. It also relates to a method for enhancing or regulating the growth of plants comprising applying said composition.
Type:
Grant
Filed:
March 29, 2012
Date of Patent:
November 12, 2019
Assignee:
Syngenta Participations AG
Inventors:
Richard Brian Perry, Ian David Perry, Timothy Norman Perry, Ulrich Johannes Haas, Philip Taylor
Abstract: The present disclosure generally provides for antimicrobial compositions having enhanced solubility and methods of using the same. The antimicrobial compositions are suitable for reducing or preventing microorganism growth, viability, or survival. The antimicrobial compositions generally include at least one antimicrobial quaternary ammonium compound and a water-soluble spacer compound or spacer interspersed therewith.
Abstract: Solutions for killing weeds include a herbicide admixed with a buffered amine oxide. The synergism between the two components reduces the amount of herbicide which must be employed to achieve an effective weed kill. Related methods involve application of the solution to the weeds to be killed.
Type:
Grant
Filed:
March 31, 2015
Date of Patent:
August 20, 2019
Assignee:
KOP-COAT, INC.
Inventors:
Hans A. Ward, Ronald Walton Clawson, Jr., Kenneth Allen Cutler, Cameron R. Scott
Abstract: Solutions for killing weeds include a herbicide admixed with a buffered amine oxide. The synergism between the two components reduces the amount of herbicide which must be employed to achieve an effective weed kill. Related methods involve application of the solution to the weeds to be killed.
Type:
Grant
Filed:
August 17, 2016
Date of Patent:
July 30, 2019
Assignee:
KOP-COAT, INC.
Inventors:
Hans A. Ward, Ronald Walton Clawson, Jr., Kenneth Allen Cutler, Cameron R. Scott
Abstract: Methods of controlling the feeding and/or breeding behavior of a target insect are disclosed in which a host plant is provided a substantial distance from a plant of interest, chemical attractant that induces the target insect to lay eggs on the host plant is applied to the host plant, application of the chemical attractant to the host plant is repeated as required to induce residual target-insect populations to lay eggs on the host plant, and wherein the behavior is controlled when a substantial number of offspring belonging to subsequent generations themselves mature and display a preference for laying eggs on the same type of host plant on which they were reared without further application of the chemical attractant is provided. Also disclosed are methods of deterring target insect feeding and breeding on plants of interest by applying toxic plant extract to the plants of interest.
Type:
Grant
Filed:
July 16, 2015
Date of Patent:
July 30, 2019
Assignee:
University of the West Indies, a Regional Institution, established by Royal Charter
Inventors:
Trevor Herbert Yee, Charah Tabetha Watson, Eric Garraway
Abstract: The present invention relates to an aqueous agrochemical spray solution containing an agrochemical active and a surfactant. The spray solution comprises a dispersed phase comprising dispersed particles which have an average particle size between 1 to 100 microns and the concentration of said dispersed particles is from about 0.001 to 5 wt %. The aqueous agrochemical spray solution is capable of reducing the volume of the fine droplets in mist whose size is less than 150 microns during spraying by at least 20% compared to the same aqueous spray solution without the presence of the surfactant. The present invention also relates to a method of reducing the spray drift of an aqueous agrochemical spray solution upon spraying with a spraying apparatus. The method includes adding the surfactant to the aqueous agrochemical spray solution in an amount effective to form the dispersed phase.
Type:
Grant
Filed:
January 12, 2018
Date of Patent:
July 23, 2019
Assignees:
AKZO NOBEL CHEMICALS INTERNATIONAL B.V., DOW AGROSCIENCES LLC
Inventors:
Jinxia Susan Sun, Shawn Zhu, Martin W. Murray, Marcus Boone, Michael Walters, Qingwen Wendy Yuan-Huffman, Christine Puglisi, Brandon Matthew Downer, Stephen L. Wilson
Abstract: Permanent hearing loss or deafness affects about 15% of people worldwide, about 40 million in the US alone. There are currently no FDA-approved drugs on the market in the US, or anywhere in the world that prevent, treat or reverse permanent hearing loss or deafness. Age-related hearing loss (ARHL) is one of the most common forms of permanent hearing loss and deafness. ARHL is the #1 neurodegenerative disorder, #1 communication disorder, and 1 of the top 3 chronic medical conditions (along with arthritis & cardiovascular diseases) of our aged population. The incidence of ARHL is increasing due to the “Baby Boomers” reaching old age, and cumulative effects of lifetime noise exposure, and widespread use of chemotherapeutic and antibiotic drugs, which are ototoxic, or have ototoxic side effects. A new drug is disclosed to prevent or slow the progression of ARHL, based upon natural, existing FDA-approved compounds that are on the market to treat other non-ARHL biomedical problems.
Type:
Grant
Filed:
June 29, 2016
Date of Patent:
July 9, 2019
Assignee:
University of South Florida
Inventors:
Robert Dana Frisina, Joseph Paul Walton, Bo Ding, Xiaoxia Zhu
Abstract: Amine salts of certain herbicides that in free acid form include at least one carboxylic acid moiety are described. Herbicide salts comprising the cation of various imidazole, piperazine, piperidine, and morpholine compounds are provided. The herbicide amine salts described are suitable for formulation into herbicidal application mixtures and/or stable concentration compositions that exhibit acceptable volatility characteristics upon application.
Type:
Grant
Filed:
October 26, 2012
Date of Patent:
July 2, 2019
Assignee:
Monsanto Technology LLC
Inventors:
Junhua Zhang, Daniel R. Wright, William Abraham
Abstract: The present disclosure, among other things, provides a composition including a nanoscale core; a plurality of capping agent entities associated on the core; an outer encapsulant layer; and a plurality of dopant entities distributed at locations selected from the group consisting of: on or within the nanoscale core, on or between capping agent entities, on or within the encapsulating layer, and combinations thereof. Provided technologies can achieve unprecedented levels of dopant entity density and/or surface localization, which, for a SE(R)RS-active agent dopant, results in dramatically improved signal intensity and/or imaging sensitivity.
Type:
Grant
Filed:
August 30, 2013
Date of Patent:
June 18, 2019
Assignee:
Sloan-Kettering Institute for Cancer Research
Inventors:
Moritz Kircher, Stefan Harmsen, Matthew Wall
Abstract: This method includes the provision of a first fluid (36) including the first phase and a first precursor polymer of the coacervate contained in the first phase, and the formation of drops of the first fluid (36) in a second fluid (40) intended to form the second phase (16). It includes the steps of introducing a second precursor polymer of the coacervate into the second fluid (40) and, during the formation of each drop (12), or once each drop (12) has been formed, for generating the coacervate layer by interaction between the first precursor polymer and the second precursor polymer at the interface between the first phase (14) and the second phase (16).
Abstract: A stable, aqueous composition containing a crosslinked, nonionic, amphiphilic polymer capable of forming a yield stress fluid in the presence of a surfactant is disclosed. The yield stress fluid is capable of suspending insoluble materials in the form of particulates and/or droplets requiring suspension or stabilization.
Type:
Grant
Filed:
September 13, 2012
Date of Patent:
April 23, 2019
Assignee:
Lubrizol Advanced Materials, Inc.
Inventors:
Shui-Jen Raymond Hsu, Krishnan Chari, Wei-Yeih Yang, Prachur Bhargava, Murat Kadir
Abstract: This disclosure relates to the field of molecules having pesticidal utility against pests in Phyla Arthropoda, Mollusca, and Nematoda, processes to produce such molecules, intermediates used in such processes, pesticidal compositions containing such molecules, and processes of using such pesticidal compositions against such pests. These pesticidal compositions may be used, for example, as acaricides, insecticides, miticides, molluscicides, and nematicides. This document discloses molecules having the following formula (“Formula One”).
Type:
Grant
Filed:
October 9, 2017
Date of Patent:
April 16, 2019
Assignee:
Dow AgroSciences LLC
Inventors:
Ronald J. Heemstra, Ronald Ross, Jr., Timothy P. Martin, Nicolaas Vermeulen, John F. Daeuble, Sr., Joseph D. Eckelbarger, Alex Nolan, Kaitlyn Gray, David A. Demeter, Ricky Hunter, Tony K. Trullinger
Abstract: Methods and compositions in which botanical oils, such as wintergreen oil, and/or isolated methyl salicylate are combined with an attractant matrix (pellets) and applied near a nest of leaf-cutting ants. These oils possess fungicidal and fungistatic properties that destroy and inhibit growth of the ant-cultivated fungus—the ant colony's sole food source—thereby promoting destruction of the colony. These oils are also highly attractive to the ants, exerting no repellent effects, encouraging transport of the fungicidal materials into the nest and ensuring that the fungal colonies come into contact with the materials and suffer mortality.
Type:
Grant
Filed:
April 29, 2016
Date of Patent:
April 9, 2019
Inventors:
Agenor Mafra-Neto, Rodrigo Oliveira Da Silva, Rafael Borges, Leyza Paloschi De Oliveira
Abstract: A composite particle comprises i) an hydrophobic particle that adheres to the cuticle of one or more species of animal infesting arthropod; and ii) at least one organic chemical compound admixed therewith, wherein the said organic chemical is capable of controlling the population of at least one animal infesting arthropod species. Experiments proved the efficacy of the particle, for example in powder form, in relation to a variety of arthropods, for example red poultry mites.
Type:
Grant
Filed:
April 12, 2011
Date of Patent:
March 26, 2019
Assignee:
Exosect Limited
Inventors:
Clare Gillian Storm, Nicola Jane Huggett
Abstract: The present invention provides both compositions comprising Methylobacterium and compositions comprising Methylobacterium that are depleted of substances that promote growth of resident microorganisms on a lettuce plant or seed. Also provided are methods for improving lettuce production, methods of making the compositions, and methods of treating a lettuce plant or seed with the compositions comprising Methylobacterium.
Abstract: This invention relates to the use of aromatic esters as adjuvants in compositions, particularly for agrochemical use, as well to compositions comprising such an aromatic ester, in combination with at least one agrochemical and at least one surfactant. The invention further extends to methods of making and using such compositions. In particular the present invention relates to such compositions when formulated as, or comprised by, an emulsion concentrate (EC), an emulsion in water (EW), a suspension of particles in water (SC), a microcapsule formulation (CS), a suspension of particles with an emulsion (SE), a dispersion concentrate (DC) or an oil suspension (OD).
Type:
Grant
Filed:
April 13, 2012
Date of Patent:
February 19, 2019
Assignee:
SYNGENTA LIMITED
Inventors:
Gordon Alastair Bell, Julia Lynne Ramsay, Raul Minguez Molina, David Stock, Gary Charles Walter
Abstract: Poly(oxyalkylene)urethane surfactants of the formula (I) R2—X—OCHN—[R1—NHCO—O—[(CH2)q—O]x—CONH—]nR1—NHCO—X—R2??(I) in which R1: an alkylene radical, a cycloalkylene radical or an arylene radical; X: —O— or —NH—; R2: a linear or branched (C1-C4)-alkyl radical, monosubstituted by a group selected from: sulfo, carboxyl and [N,N-di-(C1-C4)-alkyl]amino, or disubstituted by: carboxyl; carboxyl and hydroxyl; carboxyl and mercapto; or, if X=—O—, R2 may also be defined as [R3—O—CONH—R1—NHCO—O—]mR4 in which R3: a linear or branched (C1-C4)-alkylene radical, monosubstituted by COOH, especially a —CH2—[C(COOH)(CH3)]—CH2— radical, R1 is as defined above, and R4: C2-C22-alkyl or a —CH2—[C(COOH)(CH3)]—CH2—OH radical, and m=an integer from 1 to 10; n=an integer from 1 to 7; q=an integer from 3 to 5; and x=an integer from 10 to 70; and the water-soluble or water-dispersible salts thereof are described as a solubilizer and stabilizer in active ingredient formulations.
Type:
Grant
Filed:
July 7, 2014
Date of Patent:
February 12, 2019
Assignee:
BASF SE
Inventors:
Viet Nguyen-Kim, Murat Mertoglu, Ann-Kathrin Marguerre, Volodymyr Boyko
Abstract: A polyether dendrimer of formula (I), wherein the symbols and indices have the following meanings: each Y is independently [R1—(O—CH2—CH2)p—O—]; each Z is independently [R2—(O—CH2—CH2)q(O—CH(CH3)—CH2)r—O—]; each R1 is independently H, CH3 or C2-C4-alkyl; each R2 is independently linear or branched C8-C22-alkyl; X is H or C1-C4-alkyl; m is 1, 2, 3, 4, 5 or 6; n, o are rational positive numbers >0, with the proviso that the sum of n and o is 2m; p is a natural number from 5 to 50; q is a natural number from 1 to 50; r is 0 or is a natural number from 1 to 30, with the proviso that 5?q+r?50, and ˜ denotes the bonding of the respective group to the dendron scaffold, is useful for solubilizing sparingly-water soluble active ingredients, in particular pesticides.
Type:
Grant
Filed:
April 20, 2015
Date of Patent:
February 5, 2019
Assignee:
BASF SE
Inventors:
Murat Mertoglu, Jean-Pierre Berkan Lindner, Ann-Kathrin Marguerre, Rainer Berghaus