Patents Examined by Craig D Ricci
  • Attenuation of encrustation of medical devices using coatings of inorganic fullerene-like nanoparticles
    Patent number: 11446413
    Abstract: A new approach is presented to reduce encrustation of catheters by the application of nanoparticles. It is demonstrated that the negatively surface charged nanoparticles produce coating films comprised of long-range domains in which the nanoparticles are self-assembled into a mosaic-like order, showing a relatively small tendency to agglomerate.
    Type: Grant
    Filed: January 6, 2015
    Date of Patent: September 20, 2022
    Assignees: YEDA RESEARCH AND DEVELOPMENT CO. LTD., MOR RESEARCH APPLICATIONS LTD.
    Inventors: Reshef Tenne, David Zbaida, Racheli Ron, Ilan Kafka, Ilan Leibovitch
  • Lipoxin and lipoxin analogue mediated neuroprotection and treatments
    Patent number: 11439615
    Abstract: Methods and compositions for inhibiting or preventing neurodegeneration, specifically hippocampal, cortical, and/or retinal ganglion cell neurons (RGC), and degeneration and/or cell loss or treating related disorders and diseases comprising administering to a subject an effective amount of one or more lipoxin compounds and/or lipoxin analogues such that degeneration and/or cell loss of neurons is inhibited or prevented.
    Type: Grant
    Filed: March 9, 2018
    Date of Patent: September 13, 2022
    Assignees: University Health Network, The Regents of the University of California
    Inventors: Jeremy M. Sivak, Izhar Livne-Bar, John G. Flanagan, Karsten Gronert, Jessica Wei
  • Chromane monobactam compounds for the treatment of bacterial infections
    Patent number: 11433055
    Abstract: The present invention relates to monobactam compounds of Formula I: and pharmaceutically acceptable salts thereof. The present invention also relates to compositions which comprise a monobactam compound of the invention or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier. The invention further relates to methods for treating a bacterial infection comprising administering to the patient a therapeutically effective amount of a compound of the invention, either alone or in combination with a therapeutically effective amount of a second beta-lactam antibiotic.
    Type: Grant
    Filed: September 27, 2018
    Date of Patent: September 6, 2022
    Assignee: Merck Sharp & Dohme LLC
    Inventors: Tesfaye Biftu, Xianhai Huang, Weiguo Liu, Weidong Pan, Min Park, Alexander Pasternak, Wanying Sun, Haifeng Tang, Yi Zang
  • Treatment of cancers having alterations within the SWI/SNF chromatin remodeling complex
    Patent number: 11433068
    Abstract: This disclosure provides compositions and methods of treating cancer by inhibiting histone methyltransferases alone or in combination by synergistically inhibiting a histone demethylase, or a histone deacetylase (HDAC), or a bromodomain (BRD)-containing protein, or a B-Raf kinase. In particular, the cancers have deficient of SWI/SNF chromatin remodeling complexes because of mutations in one or more of the complex's subunit members.
    Type: Grant
    Filed: September 7, 2017
    Date of Patent: September 6, 2022
    Assignee: THE GENERAL HOSPITAL CORPORATION
    Inventors: David E. Fisher, Qing Yu Weng, Shinichiro Kato
  • Pimarane diterpenoids for use in wound healing and angiogenesis
    Patent number: 11426360
    Abstract: Methods and compositions are described for use in encouraging angiogenesis and skin healing as may be utilized in wound treatment as well as in encouragement of angiogenesis in disease. Compositions include an effective amount of a natural pimarane diterpenoid extract of Hymenocrater elegans, or a derivative, analogue, or homolog thereof. Compounds based upon this natural extract have been found to be highly effective in vascular formation and skin closure while exhibiting low toxicity.
    Type: Grant
    Filed: September 23, 2019
    Date of Patent: August 30, 2022
    Assignees: University of South Carolina, TIGHitco, Inc.
    Inventors: Ehsan Jabbarzadeh, Sara Eslambolchimoghadam
  • Compositions and methods for treating lysosomal storage disorders
    Patent number: 11426406
    Abstract: Provided herein are methods of treating a lysosomal storage disorder (LSD) in a subject and methods of promoting lysosomal clearance in one or more cells of a subject.
    Type: Grant
    Filed: February 9, 2018
    Date of Patent: August 30, 2022
    Assignee: GEORGETOWN UNIVERSITY
    Inventor: Charbel Moussa
  • Compounds for treating Rac-GTPase mediated disorder
    Patent number: 11427574
    Abstract: This disclosure relates to compositions including certain compounds identified by a quantitative, high throughput assay to be effective in the treatment of a Rac-GTPase mediated disorder (e.g., acute lymphoblastic or chronic myelogenous leukemia), as well as methods for the manufacture of and the use of these compounds for treating a Rac-GTPase mediated disorder.
    Type: Grant
    Filed: July 2, 2020
    Date of Patent: August 30, 2022
    Assignee: Children's Medical Center Corporation
    Inventors: David A Williams, Serena De Vita
  • Low dose product and method for treating diarrhea
    Patent number: 11419868
    Abstract: A method of treating diarrhea in a patient includes administering a dose of 2.0-7.0 mg of cetirizine and 3.0-15.0 mg of famotidine.
    Type: Grant
    Filed: July 16, 2019
    Date of Patent: August 23, 2022
    Assignee: White Sands Pharma LLC
    Inventors: Reed B. Hogan, II, Joseph A. Fix
  • Use of cannabinoids in the treatment of inflammatory skin diseases
    Patent number: 11413266
    Abstract: The present invention relates to the use of one or more cannabinoids in the treatment of an inflammatory skin disease. Preferably the one or more cannabinoids are taken from the group consisting of: cannabidiol (CBD), cannabidiolic acid (CBDA), cannabidivarin (CBDV), cannabigerol (CBG), cannabigervarin (CBGV) and tetrahydrocannabivarin (THCV). The inflammatory skin disease may be caused by one or more of the following: microbial infection-induced dermatitis; solar dermatitis; atopic dermatitis; and allergic contact dermatitis.
    Type: Grant
    Filed: September 29, 2016
    Date of Patent: August 16, 2022
    Assignee: GW Pharma Limited
    Inventors: Tamás Biró, Colin Stott, Vincenzo Di Marzo
  • Carbonic anhydrase enzymes for regulating mast cell hematopoiesis and type 2 inflammation
    Patent number: 11406637
    Abstract: The invention provides methods and compositions that are useful for treating allergic diseases, bacterial infections, fungal infections, viral infections, mastocytosis, mast cell-mediated inflammation and parasite infections (e.g., helminth infections).
    Type: Grant
    Filed: July 28, 2020
    Date of Patent: August 9, 2022
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventor: Mark C. Siracusa
  • Treatment of intrahepatic cholestatic diseases
    Patent number: 11406611
    Abstract: Treatment of intrahepatic cholestatic diseases by therapy with MBX-8025 or an MBX-8025 salt.
    Type: Grant
    Filed: October 3, 2020
    Date of Patent: August 9, 2022
    Assignee: CymaBay Therapeutics, Inc.
    Inventors: Pol Boudes, Charles A. McWherter
  • Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto
    Patent number: 11399540
    Abstract: This disclosure relates to the field of molecules having pesticidal utility against pests in Phyla Arthropoda, Mollusca, and Nematoda, processes to produce such molecules, intermediates used in such processes, pesticidal compositions containing such molecules, and processes of using such pesticidal compositions against such pests. These pesticidal compositions may be used, for example, as acaricides, insecticides, miticides, molluscicides, and nematicides. This document discloses molecules having the following formula (“Formula One”).
    Type: Grant
    Filed: June 18, 2018
    Date of Patent: August 2, 2022
    Assignee: CORTEVA AGRISCIENCE LLC
    Inventors: Natalie C Giampietro, Jeffery D Webster, David A Demeter, Thomas C Sparks
  • Drug delivery system for the delivery of antiviral agents
    Patent number: 11400186
    Abstract: This invention relates to novel implant drug delivery systems for long-acting delivery of antiviral drugs. These compositions are useful for the treatment or prevention of human immunodeficiency virus (HIV) infection.
    Type: Grant
    Filed: May 8, 2017
    Date of Patent: August 2, 2022
    Assignee: Merck Sharp & Dohme LLC
    Inventors: Stephanie Elizabeth Barrett, Marian E. Gindy, Li Li, Ryan S. Teller, Seth P. Forster
  • Resorcinol derivatives for their cosmetic use
    Patent number: 11401236
    Abstract: The invention relates to resorcinol-derived compounds of formula (I) and also the salts thereof, the solvates thereof and the optical and/or geometrical isomers thereof, including enantiomers and diastereoisomers, the racemic mixtures thereof, alone or as a mixture. The invention also relates to a cosmetic process for depigmenting, lightening and/or bleaching keratin materials, in particular the skin, using these compounds (I).
    Type: Grant
    Filed: May 30, 2018
    Date of Patent: August 2, 2022
    Assignee: L'OREAL
    Inventors: Xavier Marat, Chunyu Ma
  • Use of cannabidiol in the treatment of epilepsy
    Patent number: 11400055
    Abstract: The present disclosure relates to the use of cannabidiol (CBD) for the treatment of Tuberous Sclerosis Complex (TSC). In particular the TSC is treatment resistant and is characterised by generalised seizures or focal seizures with impairment. The disclosure further relates to the use of CBD in combination with one or more anti-epileptic drugs (AEDs).
    Type: Grant
    Filed: June 7, 2021
    Date of Patent: August 2, 2022
    Assignee: GW Research Limited
    Inventors: Geoffrey Guy, Stephen Wright, Elizabeth Thiele
  • Amorphous pyrrolidine derivative as PPAR agonist and preparation method thereof
    Patent number: 11396493
    Abstract: The present invention relates to an amorphous pyrrolidine derivative as a PPAR agonist and a preparation method thereof.
    Type: Grant
    Filed: December 20, 2018
    Date of Patent: July 26, 2022
    Assignee: GUANGDONG RAYNOVENT BIOTECH CO., LTD.
    Inventors: Zhiliang Yuan, Zhigan Jiang, Haiying He, Xiao Zhang, Jiwen Xu, Weixiang Zhou, Jian Li, Shuhui Chen
  • Compounds reducing malodour perception and the use thereof
    Patent number: 11382848
    Abstract: The present invention relates to new malodour-counteracting agents of formula (I) or stereoisomers thereof, particularly useful in blocking the olfactory perception of androstenone, Formula (I), wherein R1, R2, R3, R4, R5, R6, R7 and X have the same meaning as that defined in the claims. The present invention also relates to consumer products comprising said agents. The present invention also relates to the use of said agents to suppress or attenuate undesirable odour, as well as to methods to suppress or attenuate undesirable odour employing said compounds.
    Type: Grant
    Filed: January 30, 2018
    Date of Patent: July 12, 2022
    Assignees: CHEMCOM S.A., GIVAUDAN S.A.
    Inventors: Pierre Chatelain, Markus Gautschi, Thierry Granier, Yannick Quesnel, Charles Stanley Sell, Alex Veithen
  • Hyaluronic acid dermal fillers crosslinked with citric acid, method for making same and uses thereof
    Patent number: 11382853
    Abstract: The present invention generally relates to hyaluronic acid-based compositions for aesthetic use, and more specifically to a dermal filler composition comprising hyaluronic acid crosslinked with citric acid or a salt thereof. Furthermore, the present invention relates to a method for preparing said dermal filler composition and its use for aesthetic purposes, in particular for skin rejuvenation and correction of fine lines.
    Type: Grant
    Filed: November 10, 2017
    Date of Patent: July 12, 2022
    Assignee: ANTEIS S.A.
    Inventors: Karine Mondon, Samuel Gavard Molliard
  • Polysubstituted benzene, preparation method thereof, and method of using the same
    Patent number: 11376228
    Abstract: A polysubstituted benzene compound, preparation method thereof, and method of using the same. The compound has a formula I or I?, where X represents carbon, sulfur, or oxygen; R1 represents a C1-16 alkyl, C2-16 alkenyl, or C2-10 alkynyl; R2 represents hydrogen, halogen, C1-16 alkyl, C2-16 alkenyl, or C2-10 alkynyl; or an aryl group or a substituted aryl group by 1-5 groups selected from halogen, C1-26 alkyl, C1-3 halogenated alkyl, O—C1-3 alkyl, hydroxyl, amino, nitro, cyano group, aldehyde group and ester group; or a heteroaryl group or a substituted heteroaryl group by 1-5 groups selected from halogen, C1-26 alkyl, C1-3 halogenated alkyl, O—C1-3 alkyl, hydroxyl, amino, nitro, cyano group, aldehyde group and ester group; the heteroaryl group is a 3-10-membered heteroaryl group including N, S, O, or a combination thereof.
    Type: Grant
    Filed: August 6, 2020
    Date of Patent: July 5, 2022
    Assignees: GENIFARM LABORATORIES INC, SOUTH CHINA UNIVERSITY OF TECHNOLOGY
    Inventors: Shifa Zhu, Tongxiang Cao, Yongdong Wang, Zhipeng Huang
  • Compositions and methods for treating disease
    Patent number: 11376278
    Abstract: Embodiments of the invention provide pharmaceutical compositions and methods for preventing and treating disease and promoting the health in subjects at risk of cardiovascular disease and/or kidney disease. Additional embodiments of the present invention provide compositions and methods useful for treating and preventing a cardiovascular disease or a kidney disease.
    Type: Grant
    Filed: August 11, 2017
    Date of Patent: July 5, 2022
    Assignee: Sulfilatec, Inc.
    Inventors: Christopher Cummings, David Shifrin