Patents Examined by D. Margaet Seaman
  • [1,7]naphthyridines as PDE4 inhibitors
    Patent number: 7468370
    Abstract: Compounds of formula I in free or salt form, wherein R1, R2 and R3 have the meanings as indicated in the specification, are useful for treating conditions mediated by of phosphodiesterase type 4 or the down-regulation or inhibition of TNF-? release, particularly obstructive or inflammatory airways diseases. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.
    Type: Grant
    Filed: December 15, 2003
    Date of Patent: December 23, 2008
    Assignee: Novartis AG
    Inventors: Alastair Denholm, Thomas Hugo Keller, Clive McCarthy, Neil John Press, Roger John Taylor