Abstract: The present invention relates to novel uses of a construct consisting of virus-like particle (VLP) structure chemically coupled to a fragment of the A?-1-42 peptide and its pharmaceutically acceptable salts (hereinafter CONSTRUCT), in particular to dosage regimens, modes of and dosage forms for the administration of a CONSTRUCT for the treatment of patients suffering from dementia, in particular dementia of the Alzheimer's type.
Type:
Grant
Filed:
November 3, 2005
Date of Patent:
January 11, 2011
Assignee:
Novartis AG
Inventors:
Ana Graf, Matthias Staufenbiel, Thomas Blättler, Paolo Paganetti