Abstract: A memory alloy is used during manufacture of a transducer. The memory of the alloy may correct for deviations or bending during manufacture, such as a superelastic alloy returning an array to a flat state after being twisted during handling. The memory of the alloy may cause a desired change in array geometry during manufacture, such as a shape memory alloy twisting an array into a curved or helix due to applied heat. The array may be fixed in place by the memory alloy or bonding after positioning by the memory alloy, preventing further substantial alteration.

Abstract: Method and apparatus for the evacuation of intracerebral hematomas comprises a minimally invasive non-operating room surgical apparatus within a neuro-navigation system that can provide real-time imaging of the ICH evacuation procedure. Apparatus uses an auger housed within an apertured lumen which, when placed in proximity to a hematoma and rotated in an appropriate direction, causes the removal of the clotty material from the hematoma. Apparatus also includes ultrasonic imaging capability and an electromagnetic tracking coil to enable real-time, three-dimensional visualization of the evacuation procedure.

Abstract: Portable optical coherence tomography (OCT) devices including at least one mirror configured to scan at least two directions are provided. The portable OCT devices are configured to provide a portable interface to a sample that can be aligned to the sample without repositioning the sample. Related systems are also provided.

Abstract: A blood flow monitor with a visual display. The monitor may include a probe monitoring circuit configured to be associated with a blood vessel. The probe monitoring circuit may transmit a burst signal and receive a reflected signal, where a frequency shift in the reflected signal represents a flow rate associated with the blood vessel. A mixer may be provided in electrical communication with the probe. A signal processing circuit in electrical communication with the output of the mixer may be configured to drive the visual display with a signal representing the flow rate associated with the blood vessel.

Abstract: An ultrasonic observation apparatus is provided with a signal amplifier which amplifies a signal of an ultrasonic wave received from a sample with an amplification factor according to a receiving depth in order to use the signal in generating a B-mode image, a B-mode image data generator which generates B-mode image data in which the amplitude of the signal of the ultrasonic wave amplified by the signal amplifier is converted into brightness for display, an amplification corrector which performs correction to cancel the influence of the amplification by the signal amplifier in order to make the amplification factor constant with respect to the signal of the ultrasonic wave amplified by the signal amplifier regardless of the receiving depth, a frequency analyzer which calculates a frequency spectrum by analyzing the frequency of the signal of the ultrasonic wave corrected by the amplification corrector, and a feature data extractor which extracts feature data of the sample by performing an approximation proces

Abstract: A transceiver for use in an ultrasound system is provided. The transceiver is configured to operate in a transmit mode and a receive mode. The transceiver comprises a high voltage switch, a low voltage switch and a resistor coupled to the high voltage switch and the low voltage switch.

Abstract: A magnetic resonance (MR)-positron emission tomography (PET) device dual modality system includes a dual modality detector system, conductors, and a PET processing device. The dual modality detector system includes a plurality of PET detector device having a framing recovery device and PET detectors, and an MR detector device having a magnetic resonance (MR) receiver. The conductors are electrically connected to the PET detectors. The PET processing device transmits modulated timing and frame synchronization signals to the PET detectors via the conductors and the framing recovery device. The frame synchronization signal is missing one or more framing signals, thereby reducing a spectral radiation of the conductors that causes interference to the MR receiver of the MR detector device. The framing recovery device detects the timing and frame synchronization signals and recovers the one or more missing framing signals.

Abstract: A biological information imaging method includes a first measurement step to measure an acoustic wave (54) generated by light (53) which is irradiated to a living body (51) from a light source (50) and which is absorbed by tissue (52) in the living body, a storage step to store first information obtained in the first measurement step, a second measurement step to measure an acoustic wave (54) generated by light (53) which is irradiated to the living body (51) from the light source (50) and which is absorbed by the tissue (52) in the living body, and a processing step to generate an image of information of the tissue in the living body by using second information obtained in the second measurement step, and the first information stored in the storage step.

Abstract: Systems, methods, and other embodiments associated with gated optical coherence tomography (OCT) are described. One example method includes generating an image control signal to control an OCT apparatus to acquire an image of an embryonic heart at a specified point in time during a cardiac cycle of the embryonic heart. The method may also include controlling the OCT apparatus to acquire the image based on the image control signal. In different examples, the image may be acquired in vivo or from an excised heart that is paced. The OCT apparatus and the embryonic heart may be housed in an environmental chamber having a set of controllable environmental factors. Therefore, the method may include detecting and controlling the set of controllable environmental factors.

Abstract: A system and method for improving available signal-to-noise ratio (SNR) and speed of MR imaging of hyperpolarized substances is disclosed. The system and method include decoupling spin effects of hydrogen nuclei from non-hydrogen nuclei of interest during sampling of MR signals therefrom. Though the hydrogen nuclei of the hyperpolarized substance may not be directly bonded to the non-hydrogen nuclei of interest, resonance splitting may still impact SNR. Long range decoupling improves T2* time, and thus preserves signal strength and available SNR.

Abstract: A system, an apparatus and a method for human health evaluation utilizing Thermal Micro Texture (TMT) mapping technology is disclosed. The method comprises scanning body areas of a patient utilizing an infrared camera, detecting abnormalities in the body of the patient, analyzing abnormalities of the patient against information stored in a database, and reporting results to the patient in a pre-determined format. The method provides an earlier discovery of disease by mapping and analyzing abnormal temperatures changes in the body, which can help prevent the disease from progressing at an early stage.

Abstract: The present invention provides an imaging probe for imaging mammalian tissues and structures using high resolution imaging, including high frequency ultrasound and optical coherence tomography. The imaging probes structures using high resolution imaging use combined high frequency ultrasound (IVUS) and optical imaging methods such as optical coherence tomography (OCT) and to accurate co-registering of images obtained from ultrasound image signals and optical image, signals during scanning a region of interest.

Abstract: An ultrasonic probe is disclosed which includes a cMUT chip having a plurality of vibration elements whose electromechanical coupling coefficient or sensitivity is changed according to a bias voltage and transmitting and receiving ultrasonic waves, an acoustic lens arranged above the cMUT chip, and a backing layer arranged below the cMUT chip. An electric leakage preventing unit is provided at the ultrasonic wave transmission/reception surface side of the acoustic lens or between the acoustic lens and the cMUT chip. The electric leakage preventing unit can be, for example, an insulating layer such as a ground layer. Such a structure makes it is possible to provide an ultrasonic probe capable of preventing electric leakage from the ultrasonic probe to an object to be examined so as to improve the electric safety and an ultrasonic diagnostic apparatus using the probe.

Abstract: The present invention provides minimally invasive imaging probe having an optical encoder integrated therewith for accurately measuring or estimating the rotational velocity near the distal end of the medical device, such as an imaging probe which undergoes rotational movement during scanning of surrounding tissue in bodily lumens and cavities.

Abstract: A method of evaluating dry eye in humans wherein the flow of naturally occurring secretion to the eye is reduced or stopped due to the presence of an obstruction of a meibomian gland in the eyelid involves applying a pressure to the eyelid that mimics pressure applied during blinking; and simultaneously imaging the glands to diagnose the condition of the meibomian gland. This abstract is not to be considered limiting, since other embodiments may deviate from the features described in this abstract.

Abstract: According to embodiments, systems, devices, and methods for biological sensing with laser self-mixing sensors are disclosed. In one embodiment, one or more self-mixed laser Doppler signals may be used to detect blood flow velocity or blood vessel wall velocity. In one embodiment, a blood vessel wall compliance may be derived from the blood vessel wall velocity. In one embodiment, blood pressure may be calculated based at least in part on blood flow velocity or based at least in part on blood flow velocity and blood vessel compliance. In one embodiment, common mode noise may be removed from one or more laser signals.

Abstract: An ultrasound transducer includes a substrate and a lower electrode layer, a lower insulating layer, an upper insulating layer, and an upper electrode layer. The lower insulating layer and the upper insulating layer are arranged to be opposed to each other via an air gap section. The upper insulating layer and the lower insulating layer are different in a material and thickness and satisfy Equation 1 below. In Equation 1, K1 represents a relative dielectric constant of the lower insulating layer, K2 represents a relative dielectric constant of the upper insulating layer, T1 represents thickness of the lower insulating layer, T2 represents thickness of the upper insulating layer, ?1(x) represents a charge density distribution in the lower insulating layer, and ?2(y) represents a charge density distribution in the upper insulating layer.

Abstract: An apparatus for wide-field functional imaging (WiFI) of tissue includes a spatially modulated reflectance/fluorescence imaging (SI) device capable of quantitative subsurface imaging across spatial scales, and a laser speckle imaging (LSI) device capable of quantitative subsurface imaging across spatial scales using integrated with the (SI) device. The SI device and LSI device are capable of independently providing quantitative measurement of tissue functional status.

Abstract: A system configured to provide feedback regarding fluid parameters in the skin and/or compartments of an individual to facilitate early diagnosis of skin wounds and compartment syndromes.

Abstract: A surgical tool such as a liposuction cannula is equipped with a sensor at the tool tip. The sensor continuously analyzes the type of tissue in contact with the tip based on the electrical properties of the tissue. When encountering a tissue type that should not be disturbed, the action of the surgical tool is stopped automatically. When used for liposuction, the cannula is mechanically decoupled from the handle when the wrong type of tissue is detected thus minimizing the inertia of the part that needs to be stopped. Besides electrical sensing, other sensors, such as mechanical or ultrasonic, can be used at the tip of the surgical tool or cannula to differentiate between tissue types.