Patents Examined by Daniel Mytelka
  • Patent number: 5776760
    Abstract: Genes encoding a glyphosate oxidoreductase enzyme are disclosed. The genes are useful in producing transformed bacteria and plants which degrade glyphosate herbicide as well as crop plants which are tolerant to glyphosate herbicide.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: July 7, 1998
    Assignee: Monsanto Company
    Inventors: Gerard Francis Barry, Ganesh Murthy Kishore
  • Patent number: 5763252
    Abstract: A cDNA clone from barley, pAGL.2737, SEQ ID NO: 3, which encodes the enzyme .alpha.-glucosidase, is disclosed. A vector and microbial host containing a DNA sequence coding for the expression of barley .alpha.-glucosidase, and a DNA construct comprising a DNA sequence coding for the expression of barley .alpha.-glucosidase, together with a promoter located 5' to the DNA coding sequence and a 3' termination sequence, are also disclosed.
    Type: Grant
    Filed: April 28, 1995
    Date of Patent: June 9, 1998
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Ronald W. Skadsen, Brian K. Tibbot
  • Patent number: 5731165
    Abstract: An overall process for the preparation and recovery of 7-aminodesacetoxycephalosporanic acid (7-ADCA) via enzymatic ring expansion activity on penicillin G, using a Penicillium chrysogenum transformant strain expressing expandase.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: March 24, 1998
    Assignee: Gist-brocades, B.V.
    Inventors: Roelof Ary Lans Bovenberg, Bertus Pieter Koekman, Dirk Schipper, Adrianus Wilhelmus Vollebregt
  • Patent number: 5721133
    Abstract: Hybrid regulatory proteins are provided which contain amino acid sequences that are susceptible to cleavage by specific proteolytic enzymes. When acted upon by such enzymes, the hybrid regulatory proteins are rendered substantially less active, thereby altering the rate of production of products of indicator genes that are controlled by the regulatory proteins. Also provided are DNAs encoding such regulatory proteins, recombinant vectors and transformed eukaryotic cells containing such DNAs, and methods for identifying inhibitors of the specific proteolytic enzymes.
    Type: Grant
    Filed: June 1, 1995
    Date of Patent: February 24, 1998
    Assignee: Schering Corporation
    Inventor: Bimalendu Dasmahapatra
  • Patent number: 5688671
    Abstract: Recombinant DNA replicable in microorganisms belonging to the genus Corynebacterium, which contains a DNA fragment coding for an aspartokinase .alpha.-subunit protein originating from a bacterium belonging to the genus Corynebacterium, in which synergistic feedback inhibition by L-lysine and L-threonine is substantially desensitized, and a DNA fragment coding for an aspartokinase .beta.-subunit protein originating from a bacterium belonging to the genus Corynebacterium, in which synergistic feedback inhibition by L-lysine and L-threonine is substantially desensitized, is introduced into a microorganism belonging to the genus Corynebacterium. Thus a transformant having enhanced production and excretion speeds of L-lysine is obtained. The transformant is cultivated in an appropriate medium, and produced L-lysine is separated.
    Type: Grant
    Filed: October 27, 1995
    Date of Patent: November 18, 1997
    Assignee: Ajinomoto Co., Inc.
    Inventors: Masakazu Sugimoto, Yuri Ogawa, Tomoko Suzuki, Akiko Tanaka, Hiroshi Matsui
  • Patent number: 5645831
    Abstract: The present invention relates to a newly isolated Bacillus thuringiensis strain which exhibits insecticidal activity. The supernatant of cultures of this novel strain is also an effective insecticidal agents. Also included in the invention are the novel B. thuringiensis isolate, its supernatant and a solvent extract of the supernatant which are specifically active against corn rootworm but not against beet armyworm, nematodes or flies. These strains and supernatants may be used to treat plants infected with susceptible organisms.
    Type: Grant
    Filed: March 22, 1996
    Date of Patent: July 8, 1997
    Assignees: BioDiscovery New Zealand Ltd., AgraQuest, Inc.
    Inventors: Chris N. Chilcott, Peter Wigley, Andrew Broadwell, Sherry Darlene Heins, Pamela Gail Marrone