Patents Examined by Daniel Sullivan
  • Patent number: 8173844
    Abstract: A process for preparing O-alkylated amino alcohols of the formula (I) by reacting N-unsubstituted or N-monosubstituted amino alkoxide salts with alkyl halides, the amino alkoxide salts being formed by means of alkoxides
    Type: Grant
    Filed: December 11, 2006
    Date of Patent: May 8, 2012
    Assignee: BASF SE
    Inventors: Wolfgang Siegel, Gerd Haderlein, Tobias Stab
  • Patent number: 8173833
    Abstract: The present invention relates to a process for preparing isocyanates.
    Type: Grant
    Filed: November 6, 2007
    Date of Patent: May 8, 2012
    Assignee: BASF Aktiengesellschaft
    Inventors: Andreas Woelfert, Andreas Daiss, Torsten Mattke
  • Patent number: 8168679
    Abstract: The present invention concerns salts of Tramadol and Naproxen and their crystalline forms, and compositions thereof, for the treatment of pain, as well as their process for preparation.
    Type: Grant
    Filed: July 31, 2008
    Date of Patent: May 1, 2012
    Assignee: Laboratorios del Dr. Esteve, S.A.
    Inventors: Helmut Heinrich Buschmann, Antoni Torrens-Jover, Josep Mas-Prio, Jordi Benet-Buchholz, Lluis Sola-Carandell, Jordi Carles Ceron-Bertran
  • Patent number: 8168832
    Abstract: The invention relates to novel 2,4,6-trialkylphenyl-substituted cyclopentane-1,3-diones of the formula (I) in which X, Y, A, B, Q1, Q2 and G have the meanings given above, to a plurality of processes and intermediates for their preparation and to their use as pesticides and/or herbicides, and also to selective herbicidal compositions comprising, firstly, the 2,4,6-trialkylphenyl-substituted cyclopentane-1,3-diones of the formula (I) and, secondly, at least one crop plant compatibility-improving compound.
    Type: Grant
    Filed: January 3, 2007
    Date of Patent: May 1, 2012
    Assignee: Bayer Cropscience AG
    Inventors: Reiner Fischer, Stefan Lehr, Dieter Feucht, Ulrich Görgens, Olga Malsam, Alfred Angermann, Guido Bojack, Alan Graff, Christian Arnold, Thomas Auler, Martin Jeffrey Hills, Heinz Kehne, Christopher Hugh Rosinger, Jan Dittgen
  • Patent number: 8168822
    Abstract: A method of making acetic acid includes: (a) catalytically reacting methanol or a reactive derivative thereof with carbon monoxide in the presence of a homogeneous Group VIII metal catalyst and a methyl iodide promoter in a reactor vessel in a liquid reaction mixture including acetic acid, water, methyl acetate, methyl iodide and homogeneous catalyst, the reactor vessel being operated at a reactor pressure; (b) withdrawing reaction mixture from the reaction vessel and feeding the withdrawn reaction mixture along with additional carbon monoxide to a pre-flasher/post reactor vessel operated at a pressure below the reactor vessel pressure; (c) venting light ends in the pre-flasher vessel and concurrently consuming methyl acetate in the pre-flasher/post reactor vessel.
    Type: Grant
    Filed: July 7, 2009
    Date of Patent: May 1, 2012
    Assignee: Celanese International Corporation
    Inventor: Mark O. Scates
  • Patent number: 8168831
    Abstract: A non-aqueous electrolyte cell comprises a positive electrode, a negative electrode and a non-aqueous electrolyte containing a support salt. The non-aqueous electrolyte further comprises a phosphazene derivative. The phosphazene derivative having a specified structure functions as an electrode stabilizing agent or a non-combustion agent.
    Type: Grant
    Filed: June 4, 2009
    Date of Patent: May 1, 2012
    Assignee: Bridgestone Corporation
    Inventors: Masashi Otsuki, Shigeki Endo, Takao Ogino, Yasuo Horikawa
  • Patent number: 8168818
    Abstract: The invention relates to a process for preparing isocyanates in the gas phase.
    Type: Grant
    Filed: November 6, 2007
    Date of Patent: May 1, 2012
    Assignee: BASF Aktiengesellschaft
    Inventors: Andreas Daiss, Andreas Woelfert, Carsten Knoesche, Eckhard Stroefer
  • Patent number: 8168816
    Abstract: A method for producing a purified formylcyclopropane compound represented by the formula (1) comprising (A) a step of reacting a crude formylcyclopropane compound represented by the formula (1): wherein R1 represents an alkyl group or the like, with an alkali metal hydrogen sulfite to obtain an alkali metal hydroxymethanesulfonate represented by the formula (2): wherein R1 represents the same meaning as defined above and M represents an alkali metal, and (B) a step of reacting an acid, a base or a water-soluble aldehyde with the alkali metal hydroxymethanesulfonate represented by the formula (2) obtained in the above-mentioned step (A) to obtain a purified formylcyclopropane compound represented by the formula (1).
    Type: Grant
    Filed: December 12, 2006
    Date of Patent: May 1, 2012
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Kouji Yoshikawa, Ryo Minamida, Makoto Itagaki
  • Patent number: 8163965
    Abstract: The invention describes a process for the purification of iodinated aryl compounds where the purification is performed by continuous crystallization of a crude product in a solvent with removal of at least a fraction of the solvent. The continuous crystallization process is performed in one or more crystallizers at the boiling point of the content of the crystallizer.
    Type: Grant
    Filed: July 28, 2006
    Date of Patent: April 24, 2012
    Assignee: GE Healthcare AS
    Inventors: Jan Cervenka, Khalid Hussain, Arne W. Aabye
  • Patent number: 8163952
    Abstract: The invention relates to compounds corresponding to general formula (I) below: to the compositions containing same, to methods for the preparation thereof and to the use thereof in pharmaceutical compositions for use in human or veterinary medicine, or else in cosmetic compositions.
    Type: Grant
    Filed: April 24, 2008
    Date of Patent: April 24, 2012
    Assignee: Galderma Research & Development
    Inventor: Thibaud Biadatti-Portal
  • Patent number: 8158831
    Abstract: This disclosure relates to chrysene compounds with deep blue emission that are useful in electroluminescent applications. It also relates to electronic devices in which the active layer includes such a chrysene compound.
    Type: Grant
    Filed: May 30, 2008
    Date of Patent: April 17, 2012
    Assignee: E I du Pont de Nemours and Company
    Inventors: Vsevolod Rostovtsev, Reid John Chesterfield, Norman Herron, Kerwin D. Dobbs, Jeffrey A. Merlo
  • Patent number: 8158835
    Abstract: Provided is a novel fluorene compound, which is represented by the following general formula (1):
    Type: Grant
    Filed: December 14, 2006
    Date of Patent: April 17, 2012
    Assignee: Canon Kabushiki Kaisha
    Inventors: Jun Kamatani, Shinjiro Okada, Takao Takiguchi, Satoshi Igawa, Masashi Hashimoto, Minako Nakasu, Ryota Ooishi
  • Patent number: 8158825
    Abstract: The present invention relates to a novel class of modified malonate derivatives. The modified malonate compounds can be used to treat cancer. The modified malonate compounds can also inhibit histone deacetylase and are suitable for use in selectively inducing terminal differentiation, and arresting cell growth and/or apoptosis of neoplastic cells, thereby inhibiting proliferation of such cells. Thus, the compounds of the present invention are useful in treating a patient having a tumor characterized by proliferation of neoplastic cells. The compounds of the invention may also be useful in the prevention and treatment of TRX-mediated diseases, such as autoimmune, allergic and inflammatory diseases, and in the prevention and/or treatment of diseases of the central nervous system (CNS), such as neurodegenerative diseases.
    Type: Grant
    Filed: June 21, 2006
    Date of Patent: April 17, 2012
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Jonathan Grimm, Paul Harrington, Richard Heidebrecht, Jr., Thomas Miller, Karin Otte, Phieng Siliphaivanh, David Sloman, Matthew Stanton, Kevin Wilson, David Witter, Solomon Kattar, Paul Tempest
  • Patent number: 8153835
    Abstract: The present invention provides a fullerene derivative represented by the following formula (1): wherein in formula (1), R1 is a substituted or unsubstituted organic group or a hydrogen atom, and wherein in formulae (2) and (3): W is a single bond, C1-C11, alkylene, C2-C12 alkenylene, or C2-C12 alkynylene, wherein any —CH2— in the alkylene, alkenylene or alkynylene can be substituted with —O—, —S—, —COO—, or —OCO—; Z is an element belonging to group IVB; and R21 to R23 are each independently a substituted or unsubstituted C1-C20 alkyl group, a substituted or unsubstituted C2-C15 alkenyl group, or a substituted or unsubstituted C2-C15 alkynyl group.
    Type: Grant
    Filed: November 2, 2006
    Date of Patent: April 10, 2012
    Assignee: Japan Science and Technology Agency
    Inventors: Eiichi Nakamura, Yutaka Matsuo, Yu-Wu Zhong, Ayako Muramatsu
  • Patent number: 8153849
    Abstract: Methods of recovering a triarylmethyl halide from a sucrose derivatization process include the steps of (a) forming a mixture including 1) a triarylmethylated sucrose derivative including at least one triarylmethyl substituent and at least one acyl substituent on the sucrose, 2) triarylmethylated sucrose ester byproducts, and 3) an amine; (b) separating from the output of step (a) i) the triarylmethylated sucrose derivative, and ii) a mixture including the triarylmethylated sucrose ester byproducts and the amine; (c) removing the amine from the mixture of step (b) ii); (d) contacting the product of step (c) with hydrogen halide to cleave triarylmethyl groups and thereby form a crude triarylmethyl halide component; (e) contacting the crude triarylmethyl halide component with hydrogen halide to form a purified triarylmethyl halide component; and (f) recovering the triarylmethyl halide from the output of step (e).
    Type: Grant
    Filed: December 4, 2007
    Date of Patent: April 10, 2012
    Assignee: Tate & Lyle Technology Ltd.
    Inventors: Stephen C. Scherrer, Anne P. Noonan, Thomas K. Hutton
  • Patent number: 8153832
    Abstract: Pentakis(dimethylamino) disilane with general formula (1): Si2(NMe2)5Y, where Y is selected from the group comprising H, Cl or an amino group its preparation method and its use to manufacture gate dielectric films or etch-stop dielectric films of SiN or SiON.
    Type: Grant
    Filed: April 3, 2006
    Date of Patent: April 10, 2012
    Assignee: L'Air Liquide Societe Anonyme pour l'Etude et l'Exploitation des Procedes Georges Claude
    Inventor: Christian Dussarrat
  • Patent number: 8134033
    Abstract: To provide a novel polymerizable fluorocompound having a highly fluorinated norbornane structure, and a polymer obtained from the compound. Further, their production processes and a novel intermediate useful for the processes. A novel compound (1) such as a compound (11) or a compound (12), and its polymer. A compound (2) such as a compound (21) or (22), and a compound (3) such as a compound (31) or (32M), which are useful as an intermediate for the production of the compound (1), and its production process. However, each of ZA to ZE represents such as —CH(—OC(O)C(CH3)?CH2)— or —CF2, Each of WA and WB represents such as F, each of YA to YE represents such as —CH(—OH)— or —CF(CH2OH), and each of XA to XE represents such as —C(O)— or —CF2—.
    Type: Grant
    Filed: January 12, 2009
    Date of Patent: March 13, 2012
    Assignee: Asahi Glass Company, Limited
    Inventors: Yasuhisa Matsukawa, Daisuke Shirakawa, Eisuke Murotani, Naoko Shirota, Yoko Takebe
  • Patent number: 8134028
    Abstract: A process for preparing 1,2-diamino-3-methylcyclohexane and/or 1,2-diamino-4-methylcyclohexane by reacting 2,3- and/or 3,4-diaminotoluene with hydrogen at elevated pressure and elevated temperature in the presence of a heterogeneous rhodium catalyst, wherein a mixture comprising 2,3- and/or 3,4-diaminotoluene, a dialkyl ether and/or alicyclic ether as a solvent and ammonia is initially charged in an autoclave in the presence of the catalyst and subsequently hydrogenated while supplying hydrogen.
    Type: Grant
    Filed: December 14, 2005
    Date of Patent: March 13, 2012
    Assignee: BASF SE
    Inventors: Friederike Osswald, Karl Heinz Brauch, Arnd Bottcher, Jochem Henkelmann, Frederik van Laar, Till Gerlach
  • Patent number: 8134026
    Abstract: The present invention relates to an improved process for the preparation of Cilastatin Sodium of formula (I). The present invention also provides an isolation technique for Cilastatin acid from the reaction mixture.
    Type: Grant
    Filed: November 3, 2006
    Date of Patent: March 13, 2012
    Assignee: Orchid Chemicals & Pharmaceuticals Limited
    Inventors: Ganapathy Panchapakesan, Nagappan Arumugam, Pandi Suresh Pandian, Gollapalli Venkateswara Rao, Subramaniam Ganesan
  • Patent number: 8134019
    Abstract: The present invention provides a method for producing a fullerene derivative, comprising the organic group addition step B in which an organic group is further added by reacting at least a basic compound and a halogen compound with a fullerene derivative, which is obtained by addition of a hydrogen atom and an organic group in the organic group addition step A, in which an organic group is added by reacting at least a Grignard reagent and a polar substance with a fullerene or fullerene derivative.
    Type: Grant
    Filed: November 6, 2007
    Date of Patent: March 13, 2012
    Assignee: Japan Science and Technology Agency
    Inventors: Eiichi Nakamura, Yutaka Matsuo, Akihiko Iwashita