Abstract: A method of body tissue ablation includes defining a target amount of ablation energy needed to create a specified lesion in tissue in a body of a patient. Contact is made between an ablation probe and the tissue. Using the ablation probe, an ablation signal is applied to the tissue, which delivers the target amount of ablation energy during a smallest time duration permitted within a defined maximum-power constraint.

Abstract: A margin extension device and method are disclosed herein. The margin extension device can be used for ablating one or several cancer cells and can include a contact member and a plurality of electrodes. The contact member can be electrically conductive, and can electrically connect the electrodes. The margin extension device can further include one or several leads that connect the electrodes of the margin extension device to a treatment controller. The treatment controller can include a pulse generator that can generate one or several electrical pulses that generate one or several electrical fields in tissue proximate to the margin extension device.

Abstract: A fluid injection line compensation assembly for an intravascular catheter system including a balloon catheter having a guidewire lumen and a cryoballoon, includes a fluid injection line, a proximal fluid injection line stop, and a distal fluid injection line stop. The fluid injection line has a fluid discharge region positioned within the cryoballoon. The fluid discharge region includes a fluid port so that cryogenic fluid can be distributed from the fluid injection line to within the cryoballoon. The fluid discharge region is not affixed to the guidewire lumen. The proximal fluid injection line stop is positioned adjacent to the guidewire lumen, the proximal fluid injection line stop being positioned within the cryoballoon. The distal fluid injection line stop is positioned adjacent to the guidewire lumen so that the fluid discharge region is positioned between the proximal fluid injection line stop and the distal fluid injection line stop.

Abstract: A catheter device provides a balloon structure and a side-firing laser lumen within the balloon to create lesions in the pulmonary vein (PV) in the treatment of atrial fibrillation. Mounted on the balloon so as to contact the PV when the balloon is inflated are one or more electrodes which may be used in a measurement mode, a treatment mode, or both.

Abstract: A surgical device and procedure are provided for performing microsurgery, including a capsulotomy of a lens capsule of an eye. The device has an elastically deformable cutting element mounted within an elastomeric suction cup. The suction cup is attached to an arm for manipulating the device. The device can be inserted into the anterior chamber of the eye, through a corneal incision, to cut a piece from the anterior portion of the lens capsule of the eye. The device is secured against the lens capsule using suction applied by one or more suction elements. The device is then removed from the eye, with the cut piece of membrane retained within the device by suction.

Abstract: The present invention relates to the field of biomedical engineering and medical treatment of diseases and disorders. Methods, devices, and systems for in vivo treatment of cell proliferative disorders are provided. In embodiments, the methods comprise the delivery of high-frequency bursts of bipolar pulses to achieve the desired modality of cell death. More specifically, embodiments of the invention relate to a device and method for destroying aberrant cells, including tumor tissues, using high-frequency, bipolar electrical pulses having a burst width on the order of microseconds and duration of single polarity on the microsecond to nanosecond scale. In embodiments, the methods rely on conventional electroporation with adjuvant drugs or irreversible electroporation to cause cell death in treated tumors. The invention can be used to treat solid tumors, such as brain tumors.

Abstract: A forceps includes a pair of shaft members, a pair of jaw members each including a distal body and a proximal flange, and a pair of electrode plates. The proximal flanges are engaged with the respective shaft members and pivotably coupled to each other such that pivoting the shaft members pivots the distal jaw bodies. The electrode plates each includes a tissue-contacting portion disposed on the distal body of the respective jaw member and a proximal extension portion extending at least partially through the proximal flange of the respective jaw member. The tissue-contacting portion and proximal extension portion of the first electrode plate are disposed in perpendicular planes relative to each other. Likewise, the tissue-contacting portion and proximal extension portion of the second electrode plate are disposed in perpendicular planes relative to each other.

Abstract: An electrosurgical vessel sealing device that can seal biological vessels using a confined microwave field that yields a well-defined seal location with low thermal margin. The device comprises a pair of jaws that are movable relative to each other to grip biological tissue. A blade for cutting the gripped tissue is slidable between the jaws. A coplanar microstrip antenna is mounted on the inner surface of one or both of the pair of jaws to emit microwave energy into the gap therebetween. The device may comprise a separate dissector element to enable fine tissue cutting and dissection to be performed.

Abstract: A vessel sealer having a uniform pressure mechanism, detachable blade/cutter and detachable jaw assembly is disclosed. A bipolar surgical instrument, includes a jaw assembly having jaws connected to an outer tube, wherein the blade is connected to the blade pushing tube through a blade connector; a spring cap operatively engages said blade tube assembly wherein on disengagement of the said jaw assembly from an outer tube and said spring cap from said blade pushing tube are adapted to be detached from each other; a handle assembly, operatively coupled to said jaw assembly comprising a uniform pressure mechanism which contains primary spring, a secondary spring, wherein said uniform pressure mechanism enables closure of the jaws to ensure and exert a uniform pressure on the tissue and/or vessel.

Abstract: A handheld dissector includes a handle including an elongated cuff disposed at a distal end thereof. The elongated cuff defines an opening extending therethrough configured to receive a tissue specimen. The elongated cuff includes a proximal end including a cavity defined therein configured to receive a crimp ring configured to support a plurality of insulative tubes along an inner peripheral surface thereof. Each tube is configured to insulate a wire disposed therein and configured to extend from a distal end thereof. The crimp ring electrically couples to each wire. The dissector also includes a distal end configured to receive a return ring. An active lead operably couples to the crimp ring and a return lead operably couples to the return ring. An activation switch selectively energizes the dissector.

Abstract: The instrument according to the invention for electrosurgically impacting biological tissue comprises an electrode (18) as well as a light guide (21), which is connected to a light inlet window (19), which is formed by means of a fluid body (27). The light guide is connected to a light analysis device (13), so as to absorb the light, which is generated at the electrode (18) in response to the HF surgery and so as to supply it to the light analysis device (13). The light inlet window (19) is arranged at the point of origin of the light, namely immediately at the electrode, that is, at the spark, which is generated. An adulteration of the absorbed light by means of smoke or particle deposition on the light inlet window (19) can virtually be avoided.

Abstract: A surgical system comprising: a plurality of modular units, each unit comprising: a motor unit; and a surgical mechanical arm actuated by, connected to and supplied with electrosurgical power by the motor unit; and a memory configured to store a selected electrosurgical operational mode for each of the plurality of modular units.

Abstract: An energy module is disclosed. The energy module includes a control circuit and a two wire interface coupled to the control circuit. The two wire interface is configured as a power source and as a communication interface between the energy module and a neutral electrode.

Abstract: Devices, systems, and methods for treating pulmonary conditions, such as COPD and asthma, by denervating bronchial tissue using cryoablation. In one embodiment, a device for bronchial denervation comprises: an elongate body having a distal portion and a proximal portion opposite the distal portion; a treatment element at the distal portion of the elongate body; and a first recording electrode located distal to the treatment element and a second recording electrode located proximal to the treatment element, the first and second recording electrodes being configured to record electromyograms. In one embodiment, the device includes a fluid delivery element that is within the treatment element and that has a plurality of orifices aligned with an equatorial portion of the treatment element.

Abstract: A flexible tip electrode for an ablation catheter is disclosed. The catheter includes a catheter body and a hollow elongate tip electrode disposed at a distal end of the catheter body. The electrode includes a sidewall provided with one or more elongate gaps extending therethrough. The one or more elongate gaps providing flexibility in the sidewall for bending movement of the tip electrode relative to a longitudinal axis of the catheter body.

Abstract: A system and method for assessing effective delivery of ablation therapy to a tissue in a body is provided. A three-dimensional anatomical map of the tissue is generated and displayed with the map defining a corresponding volume. An index is generated corresponding to a location within the volume with the index indicative of a state of ablation therapy at the location. The index may be derived from one or more factors such as the duration an ablation electrode is present at the location, the amount of energy provided, the degree of electrical coupling between an ablation electrode and the tissue at the location and temperature. A visual characteristic (e.g., color intensity) of a portion of the anatomical map corresponding to the location is then altered responsive to the index.

Abstract: Thermal cutting surgical instruments incorporate a blade incorporating a first substrate of high thermal conductivity material in the heated portion of the blade and a support and, the first substrate of high thermal conductivity material joined to a second substrate of low thermal conductivity material in the support region of the blade; an electrically insulative dielectric layer disposed on the first surface of the first substrate and on the first surface of second substrate; an electrically resistive heating element disposed on the electrically insulative dielectric; electrically conductive power leads and electrically conductive sense leads disposed on the electrically insulative dielectric layer and that are in electrical communication with the electrically resistive heating element; and an electrically insulative dielectric overcoat layer disposed on the electrically resistive heating element and on the distal portion of the electrically conductive power leads and electrically conductive sense leads.

Abstract: A surgical instrument includes a handle, and an elongated shaft extending from the handle. An end effector extending from the elongated shaft is in communication with a source of electrosurgical energy and defines an end effector axis. A roll joint couples the end effector to the elongated shaft and includes a first tubular structure extending distally from the elongated shaft and a second tubular structure rotatably coupled to the first tubular structure. The second tubular structure supports the end effector such that the end effector is rotatable about the end effector axis.

Abstract: A bipolar surgical instrument comprises a body, first and second opposed jaws located at the distal end of a shaft, the first jaw being movable with respect to the second jaw between an open position in which the first and second jaws are spaced apart from one another, and a closed position in which the first and second jaws are adjacent one another. The first and second elongate jaw members have respective first and second electrodes. A controller is operable to determine a boiling point for tissue between the jaws using a measure of impedance therebetween.

Abstract: A cutting guard for use with a wound retractor includes a body having a lumen including a flexible inner surface with a ground contact extending therethrough. A ground guard is included having proximal and distal openings that define a guard lumen therethrough, the ground guard encapsulating the flexible inner surface of the body lumen. A biasing element is disposed within the guard lumen and encircles the flexible inner surface and biases the flexible inner surface inwardly. A cutting electrode is disposed proximate the distal opening of the ground guard and connects to a first electrical potential and the ground guard connects to a second electrical potential. Upon externalizing of tissue through the distal opening, oversized tissue forces the flexible inner surface of the body lumen and the ground contact outwardly to engage the ground guard to complete an electrical circuit and energize the cutting electrode to excise oversized tissue.