Abstract: Methods, compositions and kits for detecting Group A streptococcus in a biological sample are described. More particularly, the present disclosure provides an immunoassay in which the specificity of detection of Group A streptococcus is enhanced by addition of N-acetyl-D-glucosamine. These methods, compositions and kits are useful in convenient, reliable and early diagnosis of streptococcal infection in a human subject.
Type:
Grant
Filed:
July 31, 2012
Date of Patent:
January 1, 2019
Assignee:
Quidel Corporation
Inventors:
Peter Yan-Guo Ren, Jason McClure, Kevin S. Richardson
Abstract: Embodiments described herein include methods and assays for detecting an analyte in a sample using a plurality of control zone capture agents. Some embodiments include detection of multiple analytes in a sample utilizing a plurality of analyte binders and a control zone containing multiple control zone capture agents. In some embodiments, the multiple control zone capture agents capture a plurality of binders within one control zone. Test results are determined by comparison of the control zone signal to a test zone signal.
Type:
Grant
Filed:
June 11, 2012
Date of Patent:
November 26, 2013
Assignee:
Charm Sciences, Inc.
Inventors:
Steven J. Saul, Robert J. Markovsky, David W. Douglas