Abstract: The present disclosure provides compositions and methods for the genetic modification of cells, including, but not limited to, resting T-cells and hepatocytes. The compositions and methods can comprise lipid nanoparticles, wherein the lipid nanoparticles comprise at least one multivalent cationic bolaform amphiphilic lipid, at least one structural lipid, at least one phospholipid and at least one PEGylated lipid.

Abstract: Activated ferrate solutions, methods of their preparation, and methods of disinfecting surfaces and oxidizing pollutants in water are provided.

Abstract: The present invention is directed to processes for preparing stable 1-amino-1-cyclopropanecarboxylic acid (“ACC”) water-soluble granules comprising the steps of mixing a composition comprising ACC and water at a concentration ratio at about 2.0:1 or less to create a wet mass, extruding the wet mass to create an extrudate and drying the extrudate to create the water-soluble ACC granules, wherein the concentration of ACC and water is weight by total weight of the wet mass. The present invention is further directed to ACC granules produced by processes of the present invention.

Abstract: The present invention is directed to an aqueous composition comprising a mixture of epyrifenacil, mesotrione and pyroxasulfone. The present invention is further directed to methods of controlling weeds by applying the compositions of the present invention to a weed or an area in need of weed control.

Abstract: Methods of post-harvest protection by spraying a harvested crop of sugar beets, potatoes, or corm vegetables with a composition comprising fludioxonil and azoxystrobin, wherein the only active ingredients in the composition fludioxonil and azoxystrobin.

Abstract: This disclosure pertains to coated drug compositions and methods of preparing coated drug compositions with a low temperature silicon oxide coating. Specifically, the instant application discloses a method to coat active pharmaceutical ingredient particles using a silicon precursor and a catalyst at a low temperature.

Abstract: An object of the present invention is to provide a powder formulation for intranasal administration, which efficiently exhibits a medicinal effect, and the like. The object can be achieved by a powder formulation for intranasal administration comprising composite particles in which an active ingredient and a water-insoluble polysaccharide are cohered to each other.

Abstract: The present invention is directed to an aerosol foam composition comprising roflumilast, an emulsifier blend containing cetearyl alcohol, dicetyl phosphate, and ceteareth-10 phosphate and a hydrocarbon propellant. The aerosol foam composition is preferably an oil in water emulsion. The propellant is a mixture of liquefied hydrocarbon gases preferably a propane/isobutane/butane blend. The hydrocarbon propellant results in an aerosol foam which is stable, has consistent physical properties, excellent aesthetics, and no discernable degradation after long term or accelerated storage conditions.

Abstract: A pilling-resistant cosmetic composition is in the form of an oil in water emulsion that includes a water phase and an oily phase, and includes at least one cosmetically acceptable polymeric thickener selected from the group consisting of crosspolymers, gums, taurate based polymers, carbomers, polyacrylates, and combinations thereof, at least one ethoxylated agent in liquid form at ambient temperature in a range from about 20° C. to about 28° C. and has an HLB from about 8.5 to about 16; and at least one oil. The pilling-resistant cosmetic composition resists pilling when applied by rubbing or smoothing on a keratinous substrate.

Abstract: A balloon implantation kit includes an inflatable biodegradable balloon configured to be implanted in a human body and a hydrogel composition. In some cases, the hydrogel composition is provided in a container configured to be introduced into the biodegradable balloon. For some applications, the biodegradable balloon includes a joint spacer for treatment of a joint of a human subject, such as a subacromial spacer, a glenohumeral spacer, or a spacer for another joint, such as a knee, hip, ankle, or hand (e.g., CMC1) joint. In these applications, the biodegradable balloon is configured to be inserted into a space of a joint of the human body, and is shaped to provide mechanical support to the joint until the biodegradable balloon resorbs into the human body. For other applications, the biodegradable balloon includes a soft tissue spacer.

Abstract: A magnetoelectric nanocomposite (MEN) is described. The MEN are used as a colorectal cancer treatment. The MEN includes a shell having at least one ferroelectric compound and a rare earth (R) metal doped spinel ferrite nanoparticle (SFNP) core, of a formula of CoxMn1-xR2-yFeyOz wherein x=0.1-0.9, y=1.90-1.99, and z=3-5; and R is at least one rare earth metal selected from the group consisting of cerium (Ce), europium (Eu), gadolinium (Gd), terbium (Tb) and thulium (Tm). A method of making MENs is also provided.

Abstract: The present invention is directed to a water-soluble granule compositions comprising 1-amino-1-cyclopropanecarboxylic acid (“ACC”), a filler selected from the group consisting of lactose, dextrose, sucrose or a mixture thereof, one or more wetting agents selected from the group consisting of a non-ionic ethoxylated sorbitan, a polyoxyethylene glycol alkyl ether and an anionic dioctyl sulfosuccinate, one or more binders selected from the group consisting of polyvinylpyrrolidone and a lignosulfonate and one or more organosilicon surfactants selected from the group consisting of a polyalkyleneoxide modified heptamethyltrisiloxane and a polyether trisiloxane.

Abstract: Provided herein are compounds of Formula A, B or C that can inhibit the replication of influenza viruses, reduce the amount of influenza viruses, and/or treat influenza.

Abstract: The present invention is directed to a kit-of-parts for bleaching keratin fibers, comprising: an aqueous composition A comprising a) one or more non-acetylated sugar alcohol(s), and/or their mixtures, a bleaching composition B comprising b) one or more persalt(s) and/or peroxy salt(s), c) one or more alkalizing agent(s), and an aqueous oxidizing composition C, wherein the total concentration of compound(s) according to a) in the aqueous composition A is in the range of 1% to 50% by weight, calculated to the total weight of the aqueous composition A, and wherein the bleaching composition B comprises less than 5% by weight of water, calculated to the total weight of the bleaching composition B.

Abstract: Hair care compositions and methods for providing conditioning benefits to hair is disclosed. The hair care compositions may include one or more nonionic surfactants comprising one or more alkylpolyglucosides; one or more fatty alcohols; one or more fatty esters comprising caprylic/capric triglyceride; about 0.5 to about 30 wt. % of a fatty compound other than fatty alcohol and fatty ester; one or more silicones comprising polysilicone-11; one or more thickening agents; and water, wherein the hair care composition is an emulsion, and all weight percentages are based on the total weight of the hair care composition.

Abstract: The present invention provides a cellulose powder containing an alkali-soluble substance capable of dissolving in 17.5% by mass of aqueous sodium hydroxide solution, the content of the alkali-soluble substance being 32% by mass or more and 44% by mass or less with respect to the total mass of the cellulose powder, the use thereof, and tablets using the same.

Abstract: The disclosure features novel lipids and compositions involving the same. Nanoparticle compositions include a novel lipid as well as additional lipids such as phospholipids, structural lipids, and PEG lipids. Nanoparticle compositions further including therapeutic and/or prophylactics such as RNA are useful in the delivery of therapeutic and/or prophylactics to mammalian cells or organs to, for example, regulate polypeptide, protein, or gene expression.

Abstract: The present invention relates to a process for producing high-purity hydrosilylation products, and also to the products that may be produced by this process and to the use thereof as surfactants.

Abstract: The invention relates to a liquid concentrate comprising a plant growth regulator like prohexadione dissolved in an ionic liquid, the ionic liquid comprising an organic base and a strong acid. The ionic liquid may comprise an amine, amide, imine, imide or urea. The strong acid preferably is ethephon.

Abstract: A hair cosmetic composition including components (A) to (C), wherein the content of component (A) is 0.01 to 5.00% by mass and the content of component (B) is 5.00 to 96.77% by mass: (A) an epoxyaminosilane copolymer, which is a reaction product of compounds (a) to (d): (a) a polysiloxane having two or more oxiranyl groups or oxetanyl groups; (b) a polyether having two or more oxiranyl groups or oxetanyl groups; (c) aminopropyltrialkoxysilane; (d) a specific amine; (B) a micelle formation inhibitor selected from (b1) to (b3): (b1) an organic compound having a solubility parameter ?H of 10.0 to 15.8 MPa1/2, excluding (b3); (b2) a compound selected from ethanol and the like; (b3) an organic salt; (C) water.