Abstract: The present invention provides formulations of (E)-6-(4-Phenylcyclohexyl)-5-(3-trifluoromethylbenzyl)-1H-pyrimidine-2,4-dione, and methods of making and using the same.
Type:
Grant
Filed:
May 5, 2021
Date of Patent:
November 19, 2024
Assignee:
Corcept Therapeutics Incorporated
Inventors:
Yip-Fong Chia, Stephen Arboleda, Yan Alsmeyer, Gordon Davis, Tyler Clikeman
Abstract: The present invention relates to lenvatinib besylate, its crystalline forms and processes for making them. Furthermore, to a pharmaceutical composition comprising a therapeutically effective dose of lenvatinib besylate.
Type:
Grant
Filed:
October 1, 2019
Date of Patent:
October 1, 2024
Assignee:
Synthon B.V.
Inventors:
Luis Nogueiras Nieto, Lisardo Alvarez Fernandez, Raymond Westheim, Katerina Jelinkova
Abstract: A composition for detoxifying insect pollinators from one or more organophosphate pesticides, the composition containing microparticles comprising: (i) a phosphotriesterase; (ii) nanoparticles; and (iii) a surface active agent. Also disclosed herein is an aqueous suspension comprising the above-described detoxifying microparticles in an external aqueous medium, which may also contain an insect pollinator attractant. Also described herein is a method for detoxifying insect pollinators of one or more organophosphate pesticides, the method comprising placing the detoxifying aqueous suspension in a location accessible to the insect pollinators to permit the insect pollinators to ingest the detoxifying aqueous suspension, wherein the detoxifying aqueous suspension comprises microparticles, as described above, suspended in an external aqueous medium, typically also including an insect pollinator attractant in the external aqueous medium.
Abstract: Compositions, processes, and methods are provided including, but not limited to, a composition including a plurality of clay nanoparticles, wherein each clay nanoparticle comprises an anionic component and a cationic component wherein the anionic component has the formula (I): [(Si8MgbLic)O20(OH)4]??(I) wherein 5.5<b?6, and wherein c>0 and b/c>12.
Type:
Grant
Filed:
October 20, 2023
Date of Patent:
July 16, 2024
Assignee:
Renovos Biologics Limited
Inventors:
Richard Oreffo, Jonathan Dawson, Mohamed Mousa, Allison Shaw, Agnieszka Janeczek
Abstract: The present invention describes a secured firearm, including semi-automatic pistols and revolvers, which has a permanently mounted locking device 1 in front of a trigger guard 3 and under a barrel 4. The locking device 1 locks a locking bar 7 which restricts the movement of a slide 5 or a cylinder 30, thereby disabling the secured firearm. The locking device 1 is attached to the outside of the secured firearm. Therefor, the impact on the inside of the secured firearm can be minimized. Any kind of lock can be used as the locking device 1 as long as it is compact enough to be installed in the housing of the locking device 1. For example, a key lock, a combination lock, an electric lock, and a biometric lock such as fingerprint authentication are all applicable to the locking device 1. The locking device 1 is fixed to the secured firearm firmly with screws from inside of the frame, whereby unauthorized dismantling of the locking device 1 is prevented.
Abstract: The present invention is concerned with the art of waterfowl decoys and in particular a decoy assembly which incorporates a plurality of waterfowl bodies.
The assembly may be readily folded for storage and transport and opened and locked into position for usage. The decoy assembly comprises a central member which is flanked with a pair of secondary members. In usage these secondary members are locked into angular relationship with the central member. The assembly is molded from a high density, closed cell, polymeric material and incorporates integral molded locking means.