Abstract: This invention provides isolated nucleic acid molecules which encode inward rectifier, G-protein activated, mammalian, potassium KGA channel. This invention also provides a nucleic acid molecule of at least 15 nucleotides capable of specifically hybridizing with the above nucleic acid molecule. This invention further provides a vector comprising the isolated nucleic acid molecules which encode inward rectifier, G-protein activated, mammalian, potassium KGA channel. This invention provides a host vector system for the production of a polypeptide having the biological activity of KGA channel which comprises the above vector in a suitable host.
Type:
Grant
Filed:
June 7, 1995
Date of Patent:
March 17, 1998
Assignee:
California Institute of Technology
Inventors:
Henry A. Lester, Nathan Dascal, Nancy F. Lim, Wolfgang Schreibmayer, Norman Davidson