Abstract: A device for surgical ligation is provided, which comprises: a housing, where a pulling portion is provided therein; and an opening portion provided at one end of the housing and connected to the pulling portion, where a line delivery element is provided therein. The line delivery element comprises: a first arc unit having a first coupling portion and a slot thereon; a second arc unit having a second coupling portion corresponding to the first coupling portion; and a gear assembly comprising a plurality of gears engaging with each other, wherein a first gear is engaged with the pulling portion while a second gear is engaged with the second arc unit.

Abstract: Devices and methods for performing subcutaneous surgery in a minimally invasive manner are provided. The methods include application of reduced air pressure in a recessed area of a handpiece placed over a section of skin and drawing the section of skin and subcutaneous tissue into the recessed area. In a subsequent step a tool is inserted through a tool conduit in the handpiece and through the skin into the subcutaneous tissue, enabling the performance of the desired surgery. Common surgical procedures include dissection and ablation. The devices and methods can be directed at the treatment of skin conditions like atrophic scars, wrinkles, or other cosmetic issues, at treatments like or promoting wound healing or preventing hyperhidrosis, or can be used for creating space for various implants.

Abstract: A medical device, for insertion into an anatomical vessel, can include a sheath, a delivery wire, and a frame or vessel-engaging member. The delivery wire can have a first stop, a second stop, and a coupling area between the first and second stops. The coupling area can be disposed within and movable relative to the sheath. The frame or vessel-engaging member can have a matrix of cells, first and second tapered sections, and interlocking members. The interlocking members can be attached to the tapered sections. The interlocking members can be releasably coupled to the delivery wire at the coupling area with the interlocking members surrounded and held in the coupling area by the sheath. The interlocking members can be movable relative to the sheath, and the interlocking members can separate from each other when the interlocking members are positioned distal to the sheath.

Abstract: A system for removing obstructions from a blood vessel comprises a clot retrieval device and a catheter. The clot retrieval device comprises a clot engaging element attached to the distal end of an elongate shaft. The elongate shaft has a shaft proximal section, a shaft distal section and a shaft intermediate section between the shaft distal and proximal sections. The catheter has a catheter proximal section, a catheter distal section, and a catheter intermediate section between the proximal and distal sections. The maximum diameter of a shaft proximal section is greater than an inner distal lumen of the catheter distal section.

Abstract: Delivery devices, systems, and methods for delivering implantable leadless pacing devices are disclosed. An example delivery device may include a proximal section including a deflection mechanism for deflecting the proximal section, and a distal holding section extending distally of a distal end of the proximal section and defining a cavity therein for receiving an implantable leadless pacing device. The delivery device may include more than one deflection mechanism for deflecting the proximal section at multiple deflection regions. The delivery device may include more than one tubular member that are translatable relative to one another, and the one or more tubular members may include fixed curve portions. The delivery device may include an atraumatic or bumper tip at the distal end of the holding section.

Abstract: An endoscopic surgical device comprising a slotted clear cannula, a blade and a housing, wherein the cannula is attached to the housing, and wherein the blade is enclosed in the housing and is slidable into the cannula is disclosed. The blade is enclosed within the housing and cannula, and has a horizontally-oriented pushing component and a vertically-oriented cutting component that protrudes through the slot of the cannula. A method for a performing an operative procedure on a target tissue in a subject using the endoscopic surgical device is also described.

Abstract: A recanalization catheter for facilitating re-entry into a lumen of a blood vessel from a subintimal space. The catheter includes an inflatable balloon mounted on a distal end region of the catheter shaft of the catheter. The catheter shaft includes a guidewire lumen having a distal opening and a lateral opening in a distal region of the catheter shaft proximal of the distal opening, and an inflation lumen in fluid communication with the balloon. The balloon is configured to be inflated in the subintimal space to a first inflation state at inflation pressures below a threshold inflation pressure to orient the lateral opening toward the lumen of the blood vessel, and inflated to a second inflation state at inflation pressures above the threshold inflation pressure. The catheter includes means for retaining the balloon in the first inflation state at pressures below the threshold inflation pressure.

Abstract: A stereotactic system with customizable and interoperable components for implantation of intracranial implants is provided. The stereotactic system can include a NeuroHat stereotactic device that attaches directly to the skull of an animal subject to protect chronic intracranial implants without interfering with the normal activities of the animal subject. The stereotactic system can also include a drill guide for accurate placement of burr holes and implant shuttles designed to be interoperable with other components of the NeuroHat stereotactic device for accurate placement and secureability.

Abstract: A tissue retrieval system can include a tissue retrieval bag with an elongate profile. The tissue retrieval bag can have a relatively large volume, but be rollable to a stowed configuration to fit in a relatively small diameter introducer. The tissue retrieval system can include one or more support arms coupled to the tissue retrieval bag, the support arms biased to position the tissue retrieval bag in an access position once deployed from the introducer. A tissue retrieval system can have a hybrid tissue retrieval bag including material properties that vary along the depth of the bag from an open end to a closed end. A tissue retrieval bag can be used in conjunction with an introducer, or as a stand alone tissue retrieval bag.

Abstract: An apparatus for sealing a puncture through a vessel wall including a positioning assembly, a sheath releasably engaged with the positioning assembly, and a support member axially advanceable through the sheath. The positioning assembly includes a positioning element positioned at a distal portion of the positioning assembly and a sealant disposed at a distal portion of the positioning assembly. The sheath guides the sealant and positioning assembly to the puncture in the vessel wall.

Abstract: Exemplary embodiments of method and apparatus are provided for resurfacing of skin that includes formation of a plurality of small holes, e.g., having widths less than about 1 mm or 0.5 mm. For example, such small holes can be produced using a mechanical apparatus that includes one or more abrading elements provided at the end of one or more rotating shafts, thus avoiding generation of thermal damage as occurs with conventional laser resurfacing procedures and devices. The holes thus formed can be well-tolerated by the skin, and may exhibit shorter healing times and less swelling than conventional resurfacing procedures. The fractional surface coverage of the holes can be between about 0.1 and 0.7, or between about 0.2 and 0.5. The method and apparatus can produce cosmetic improvements in the skin appearance by eliciting a healing response.

Abstract: A surgical drive apparatus includes a rotating shaft of a sectioning device and a drive unit having a motor disposed in a motor chamber, in which the motor rotationally couples to the rotating shaft as the rotating shaft extends through an end of the motor chamber. A suction chamber is defined by an interior of a cap, in which the end of the motor chamber is receptive to the cap for sealing engagement with the drive unit, and a rotary tool such as the sectioning device extends through the cap for rotational movement relative to the cap while maintaining fluid communication with the suction chamber. For evacuation of surgical material, an outflow tube is in fluid communication with the suction chamber for providing a fluid path to the suctioning device via the suction chamber. The drive protrudes from the motor chamber which is sealed to allow cleaning and sterilization.

Abstract: A dilation catheter comprises a handle, a guidewire, a dilation catheter, a guidewire movement mechanism, and dilation catheter movement actuator. The guidewire movement mechanism is configured to translate to thereby cause translation of the guidewire relative to the handle. The dilation catheter movement mechanism is configured to translate to thereby cause translation of the dilation catheter relative to the handle. The guidewire movement mechanism also includes a rotation mechanism configured to impart rotation upon the guidewire. The rotation mechanism may include features configured to limit the amount that the guidewire may rotate. The rotation mechanism may also include features configured to convert linear movement of an actuator into rotational movement of the guidewire. The dilation catheter may include features configured to provide for side entry of the guidewire into the dilation catheter.

Abstract: A catheter system includes an introducer sheath and a delivery catheter having an external surface. A sleeve connector is supported on and axially movable relative to the external surface of the delivery catheter. A collapsible sleeve has a first end attached to the external surface of the delivery catheter at a first attachment and a second end attached to the sleeve connector at a second attachment. The catheter system includes a medical device placement configuration in which the delivery catheter is received through the introducer sheath, the sleeve connector is removably attached to the introducer sheath, and the collapsible sleeve is positioned radially between the external surface of the delivery catheter and an internal surface of the introducer sheath.

Abstract: Devices, systems, and methods for transradial access. In at least one embodiment of a device for providing access to a vessel or other luminal organ of the present disclosure, the device comprises a needle having a needle tip, a sheath positioned around at least part of the needle, the sheath defining an aperture at a distal sheath end, and a protractor in communication with the needle, whereby engagement of the protractor causes the needle tip to protract from the sheath, and whereby release of the protractor causes the needle tip to retract into the sheath.

Abstract: A method, apparatus, and system for cutting anatomic members, such as ligaments, in surgical procedures such as carpal tunnel release, plantar fasciotomy, gastroc release, cubital tunnel release, and tarsal tunnel release is disclosed. The apparatus includes a guide tool for guiding a knife and a scope during surgery which may be employed with a translating knife. Relevant features include a knife stop for preventing the knife from inadvertently raising out of the knife channel, indicia viewable to show the proper orientation for the guide tool, a self dilating tip and channel design on the guide tool, a cover piece and/or pivotable panel system for preventing ligaments and other anatomy from getting caught in the guide tool, a pivot pin and groove system for stabilizing the knife and also assuring that the knife blade is not inadvertently raised out of the channel, and a use indicator employable to prevent re-use of the device.

Abstract: A surgical clamp jaw is disclosed, having an inner profile and a deflection control profile opposite the inner profile. In one embodiment, the inner profile has a first substantially concave profile in an unclamped position and a second substantially flat profile in a clamped position. In one embodiment, the deflection control profile has one or more sets of corresponding abutment surfaces, at least one set of which is not contacting each other when the inner profile is in the unclamped position and which is contacting each other when the inner profile is in the clamped position. In one embodiment, the surgical clamp jaw defines one or more flexion assistance voids, wherein at least one of the one or more flexion assistance voids is in contact with a gap between one of the one or more sets of corresponding abutment surfaces.

Abstract: An apparatus for treating regurgitation of blood through a diseased heart valve having at least two leaflets includes a lollipop-shaped body member having a proximal end portion, a distal end portion, and an intermediate portion extending between the end portions. The intermediate portion includes an expandable occluding member having an adjustable diameter so that, during at least a portion of the cardiac cycle, at least one of the heart leaflet coapts with a portion of the occluding member to mitigate or prevent regurgitation of blood through the diseased heart valve. The proximal end portion is physically connected to the occluding member and includes a connecting mechanism for operably mating with an adjustment member for adjusting the position and diameter of the occluding member within the diseased heart valve. The distal end portion includes an anchoring member for securing the apparatus in a heart chamber containing the diseased heart valve.

Abstract: An embodiment includes an apparatus comprising: a hollow needle with a narrowed inner diameter in a distal third of the needle; and a flexible chord coupled to proximal and distal conduits; wherein the distal conduit is in the needle and distal to the narrowed inner diameter and the proximal conduit is in the needle and proximal to the narrowed inner diameter; wherein: (a)(i) long axes of the proximal and distal conduits are substantially parallel to a long axis of the needle when the proximal and distal conduits are in the needle, and (a)(ii) the proximal and distal conduits are configured to rotate when deployed from the needle such that their long axes are not parallel to a long axis of the chord when the chord is fully extended. Other embodiments are described herein.

Abstract: The invention relates to a device for controlling corporeal structures, especially for introducing puncture needles or operation probes. Said device comprises a base plate (1), at least one base holder (2) applied to the base plate (1), and holding rods (3, 4) that are fixed to the base holder in a fixed manner and are used to hold and position a targeting device (10) for a medical instrument (8). The aim of the invention is to create one such device in such a way that it has a simple structure and can guide medical instruments in a variable and precise manner. To this end, the targeting device (10) is mounted on two adjustment arms (7) that can be respectively displaced in the X and/or Y plane, on the free ends of the holding rods (3, 4), by means of an actuating drive (6).