Patents Examined by David Duzo
  • Herpes simplex virus amplicon mini-vector gene transfer system
    Patent number: 5830727
    Abstract: A novel HSV mini viral vector is disclosed. The vector comprises HSV and EBV genes which allow it to remain in episomal state, to have very high transfection and infection, and to tolerate up to 140 kb of foreign DNA. Techniques and genetic constructs for producing the vectors, for constructing the vectors and transfection and infection to recipient cells are disclosed.
    Type: Grant
    Filed: December 26, 1995
    Date of Patent: November 3, 1998
    Assignee: Human Gene Therapy Research Institute
    Inventors: Suming Wang, Charles J. Link, Jr.