Abstract: Exemplary embodiments of apparatus and method for obtaining one or more portions of biological tissue (“micrografts”) to form grafts are provided. For example, a hollow tube can be inserted into tissue at a donor site, and a pin provided within the tube can facilitate controlled removal of the micrograft from the tube. Micrografts can be harvested and directly implanted into an overlying biocompatible matrix through coordinated motion of the tube and pin. A needle can be provided around the tube to facilitate a direct implantation of a micrograft into a remote recipient site or matrix. The exemplary apparatus can include a plurality of such tubes and pins for simultaneous harvesting and/or implanting of a plurality of micrografts. The harvested micrografts can have a small dimension, e.g., less than about 1 mm, which can promote healing of the donor site and/or viability of the harvested tissue.

Abstract: A tissue ligating device to which a suture is attached and which ligates a tissue includes a suture fix member which is attached to the suture, and which includes a housing part which one part of the suture can be hooked; and a hooked suture locking part configured to prevent the suture hooked in the housing part from disengaging from the housing part.

Abstract: An end effector of an ultrasonic surgical instrument is provided, the ultrasonic surgical instrument having a manipulatable structure, a body portion operatively connected to the manipulatable structure and having a distal end, a transducer, and the end effector being supported on the distal end of the body portion, the end effector including a plurality of resonant member elements, each resonant member operatively connected to a transducer of the plurality of transducers for effecting vibrations along the length of the resonant member, and including an operating surface configured to effect tissue dissection, cutting, coagulation, ligation and/or hemostasis, wherein a displacement curve associated with the vibrations of a first one of the plurality of resonant members is offset relative to the displacement curve associated with the vibrations of a second one of the plurality of resonant members.

Abstract: A dermatological skin treatment device is provided. The device comprises a handpiece and a cutting tool, wherein the tool is inserted through the conduit and percutaneously inserted into a tissue disposed within a recessed area of the handpiece. The device and method cut the fibrous structures under the skin that cause cellulite at an angle substantially parallel to the surface of the skin and replace these structures with a non-cellulite forming structure by deploying a highly fibrous mesh through a single needle hole to create a highly fibrous layer directly or through wound healing processes.

Abstract: A needle cover is disclosed which includes a site preparation tip at a distal end of a needle cover body. The tip may be configured with rounded and/or beveled edges in order to facilitate material removal from a cannulation site. The proximal end of the needle cover body may include features to facilitate handling, removal of the needle, and operation of the needle cover in removing material, such as a scab, from a cannulation site.

Abstract: A control system for controlling movement of a medical device delivery system, a stent delivery system and a method for controlling movement of a medical device delivery system are provided. The control system includes a rotatable gear operably connected to a first movable member and a second movable member movable by the rotatable gear. The first movable member is operably connected to the first shaft and the second movable member operably connected to the second shaft. The first movable member moves the first shaft and the second movable member moves the second shaft to change a position of the first shaft relative to the second shaft and to change a configuration of a medical device operably connected to the first shaft and the second shaft.

Abstract: A robotic system for use in Minimally Invasive Surgery (MIS) is provided that, in various aspects of this specification, comprises at least one elongated shaft known as the robotic arm. In certain aspects, the robotic arm is provided with an independent roll wrist mechanism, which can allow for imparting the roll motion to the end effectors while mitigating or potentially eliminating the need of rotating the entire robotic arm, thus ensuring independent movement of end effectors. The independent movement of the end effectors sweeps a considerably smaller conical volume, as compared to that swept by the entire robotic arm, thereby reducing the likelihood of collisions with neighboring tissues or organs.

Abstract: A retrieval portion is attached to an implantable device to facilitate retrieval of the implantable device in the unlikely event of embolization. The retrieval portion may comprise one or more loops, or a plurality of extensions. Methods of retrieving an implantable device are disclosed. Various adapters are disclosed for use with a conventional snare for grasping an implantable device.

Abstract: A method of performing a bariatric procedure through a natural body orifice is disclosed. The method comprises the step of providing a surgical instrument, comprising a handle portion, an elongated portion extending distally from the handle portion, and an end effector disposed adjacent a distal end of the elongated portion. The method also comprises the steps of inserting the surgical instrument through a natural body orifice of a patient such that the end effector is adjacent a portion of the patient's stomach, and using the surgical instrument to perform a surgical task.

Abstract: Apparatus and methods are provided for flaring a stent deployed within a branch vessel including an ostium communicating with a main vessel, a first end of the stent extending at least partially from the branch. A catheter is provided that includes a first balloon carried on its distal end, and a second balloon that includes a distal section overlying at least a portion of the first balloon and a proximal section. The catheter distal end is introduced into the main vessel and positioned through the ostium and stent into the branch until the first balloon is disposed within the stent. The first balloon is expanded to anchor the stent, and the second balloon is expanded to flare the first end of the stent. Optionally, the first balloon is expanded further, e.g., to expand the stent within the branch body lumen and/or dilate the lesion.

Abstract: A tissue retrieval system can include a tissue retrieval bag with an elongate profile. The tissue retrieval bag can have a relatively large volume, but be rollable to a stowed configuration to fit in a relatively small diameter introducer. The tissue retrieval system can include one or more support arms coupled to the tissue retrieval bag, the support arms biased to position the tissue retrieval bag in an access position once deployed from the introducer. A tissue retrieval system can have a hybrid tissue retrieval bag including material properties that vary along the depth of the bag from an open end to a closed end. A tissue retrieval bag can be used in conjunction with an introducer, or as a stand alone tissue retrieval bag.

Abstract: Retrievable vena cava filters for the temporary or permanent prevention of Pulmonary embolism (PE) are disclosed. A filter in accordance with the present invention has a tube-within-tube structure with overlapping semi-spheres. The semi-spheres comprise a plurality of expandable legs. The first tube may have a first set of expandable legs and a plurality of slots allowing for deployment of a second or third set of expandable legs on the second tube. The filter of the present invention may be retrieved by a catheter and snare. The third set of expandable legs conveys the vector force from the closing of the first set to the second set to cause it to collapse.

Abstract: A medical cutting instrument for cutting muscles and tendons, with an instrument body that includes a handle on its proximal end and at least one cutting knife in the area of its distal end. To provide a medical cutting instrument that guarantees ease of handling and simple structure along with secure cutting of the muscle/tendon tissue, the instrument body should be of grooved configuration in the area of its cutting knife in such a way that the instrument body includes a hollow space extending in the longitudinal direction of the instrument body to receive and guide the muscle/tendon tissue that is to be cut, such that the instrument body includes an opening extending in the longitudinal direction of the instrument body and the cutting knife constitutes a side of the instrument body.

Abstract: A dermatological skin treatment device is provided. The device comprises a handpiece and a cutting tool, wherein the tool is inserted through the conduit and percutaneously inserted into a tissue disposed within a recessed area of the handpiece. The device and method cut the fibrous structures under the skin that cause cellulite at an angle substantially parallel to the surface of the skin and replace these structures with a non-cellulite forming structure by deploying a highly fibrous mesh through a single needle hole to create a highly fibrous layer directly or through wound healing processes.

Abstract: A dermatological skin treatment device is provided. The device comprises a handpiece and a cutting tool, wherein the tool is inserted through the conduit and percutaneously inserted into a tissue disposed within a recessed area of the handpiece. The device and method cut the fibrous structures under the skin that cause cellulite at an angle substantially parallel to the surface of the skin and replace these structures with a non-cellulite forming structure by deploying a highly fibrous mesh through a single needle hole to create a highly fibrous layer directly or through wound healing processes.

Abstract: In one embodiment the apparatus includes a first retractor, a second retractor, and a shaft. The shaft defines a central channel extending from a first end portion of the shaft to a second end portion of the shaft. The first retractor and the second retractor are configured to collectively form a lumen. The shaft is configured to be disposed within the lumen. In one embodiment method of disposing a graft within a body of a patient, includes making an incision in the body of the patient, inserting a medical device into the body of the patient through the incision, removing the shaft of the medical device from the body of the patient, and moving the first refractor within the body of the patient away from the second retractor.

Abstract: An intraocular lens inserter can include an energy storage portion, an actuator portion, and a lens support portion. The energy storage portion can include a compressible energy storage device, such as a compressible fluid, springs, and other devices. The inserter can include an actuator portion operating with a substantially incompressible fluid, such as liquids or other noncompressible fluids. The actuator can be configured to provide an operator with control over the release of energy from the energy storage portion so as to move a plunger for the discharge of a lens from an intraocular lens cartridge.

Abstract: In one embodiment, the present invention includes a method for holding soft tissue in apposition with a bone using a suture, the method including engaging the soft tissue with an engaging portion of a suture thread; engaging an end of the suture thread with a rotatable shaft of an anchor; implanting the rotatable shaft in the bone; and rotating the shaft in a first direction to wrap the engaged suture thread onto the shaft thereby increasing tension on the suture and on the soft tissue.

Abstract: A dermatological skin treatment device is provided. The device comprises a handpiece and a cutting tool, wherein the tool is inserted through the conduit and percutaneously inserted into a tissue disposed within a recessed area of the handpiece. The device and method cut the fibrous structures under the skin that cause cellulite at an angle substantially parallel to the surface of the skin and replace these structures with a non-cellulite forming structure by deploying a highly fibrous mesh through a single needle hole to create a highly fibrous layer directly or through wound healing processes.

Abstract: For producing a skin opening for minimally invasive surgery an instrument is employed, comprising a grip (10) and a puncture awl (16). The puncture awl (16) is provided on the distal end of a grip (10), which distal end forms a stop surface (12), which limits the penetration depth of the puncture awl (16).