Abstract: The invention provides methods and compositions for determining whether a subject containing a stent immobilized in a blood vessel has asymptomatic stent thrombosis or is at risk of developing clinically symptomatic stent thrombosis. In one approach, the method involves imaging a region of the blood vessel that contains the stent using a probe that contains a fluorochrome, for example, a near-infrared fluorochrome, and a targeting moiety that binds a molecular marker indicative of the presence of asymptomatic stent thrombosis or the development of symptomatic stent thrombosis. To the extent that the subject displays one or more such markers, the probe binds to the markers and increases the local concentration of the probe in the vicinity of the stent. The imaging method identifies those patients that display a higher density of such markers in the vicinity of the stent. As a result, those patients can be monitored for, and/or treated to prevent, symptomatic stent thrombosis.

Abstract: An implantable medical device includes a radiolucent member provided with an x-ray mirror that reflects incident x-ray radiation to enable visualization of the device. The x-ray mirror includes a multilayer nanolaminate having alternating layers of a first metal or ceramic layer deposited by atomic layer deposition having a first refractive index, and a second metal or ceramic layer deposited by atomic layer deposition having a second refractive index that is different from the first refractive index. The nanolaminate includes a total of at least four layers.

Abstract: Provided herein is a vertebral distractor-inserter comprising a pair of arms comprising a first arm having a proximal end and a distal end and a second arm having a proximal end and a distal end, wherein the distal end of the first opposing arm is laterally offset from the distal end of a second arm thereby comprising a pair of laterally offset opposing arms, a driving rod extending between the pair of laterally offset opposing arms, and a drive mechanism in mechanical communication with the driving rod. A vertebral distractor-inserter comprising a pair of opposing arms, a housing in mechanical communication with the arms and rotatable about an axis extending between the arms, and a driving rod extending through at least a portion of the housing and between the arms. A vertebral distractor-inserter adapted for single-handed use. A vertebral distractor-inserter having an implant depth adjustor. Methods for distracting adjacent vertebrae and inserting an implant using the device described herein.

Abstract: Method and set of surgical instruments for fitting a shoulder prosthesis, and the shoulder prosthesis. The proposed method seeks to interpose a bone graft between the previously prepared glenoid surface (G) of a scapula (S) of a patient's shoulder and the face of a glenoid prosthetic component opposite the articular surface. The set of instruments permit the bone graft to be taken from the upper epiphysis of the humerus (H), either in situ or ex vivo.

Abstract: An acetabular hip implant includes an acetabular shell component having a first feature and a first insert having a second feature that cooperates with the first feature of the acetabular shell component and further includes a third feature. The implant further includes a second insert having a fourth feature that cooperates with the third feature of the first insert and further includes a fifth feature. A femoral head component includes a sixth feature that cooperates with the fifth feature. Interaction between the first and second features, between the third and fourth features, and between the fifth and sixth features mechanically constrains the acetabular hip implant to prevent dislocation of the femoral head during rotation.

Abstract: The disclosure describes implantable medical products, that include dry or partially hydrated biocompatible constructs comprising collagen fibers configured to expand in situ after implantation to frictionally engage a bone tunnel wall to thereby affix the construct in the bone tunnel.

Abstract: A novel cardiovascular stent for preventing vascular stenosis is disclosed. The basic components of the cardiovascular stent of the present invention include V-shape rib unit, multi-link unit and connective ring unit. In addition, each ring rib part is formed by a plurality of double V-shape rib units that are connected together via the bridging portions of the multi-link units. Also, each connective part comprises a plurality of connective ring units. The integrally formed stent of the present invention is formed with the ring rib parts that are connected together by the connective parts.

Abstract: Provided is a stent wherein the water-swellable polymer fine particles applied thereto rarely peel off even when the stent is deformed or when the water-swellable polymer fine particles are swollen. A stent wherein a plurality of water-swellable polymer fine particles are chemically fixed on the stent surface in a dispersed state is provided.

Abstract: A knee joint prosthesis assembly can include a femoral component that has a medial and a lateral condyle portion connected by a patellar track portion. The femoral component can form an opening between the medial and lateral condyles. A tibial component can have a medial portion that includes a first engagement structure and a lateral portion that includes a second engagement structure. A medial bearing can have a third engagement structure formed thereon that selectively engages the first engagement structure. A lateral bearing separately formed and independent from the medial bearing can have a fourth engagement structure formed thereon that selectively engages the second engagement structure.

Abstract: A system and method for correcting misshaped ears using a molding device having one or more braces supporting a scaphal mold. The one or more braces and the scaphal mold are adapted to retain the helix and the helical rim of a misshaped ear within a space defined between the one or more braces and the scaphal mold, and to maintain a substantially correct anatomical shape of the helix and the helical rim.

Abstract: Implant devices, and method of using the same, are provided. The implant devices have an articular end and a stem, the stem having an oval-shaped cross-section. The articular end has an upper surface, a side surface, and a lower surface. The upper surface and lower surface each intersect the side surface. The upper surface has a first surface curvature, a central surface curvature, and a second surface curvature. The stem extends from the lower surface in a direction away from the upper surface of the articular end.

Abstract: In a femoral head cap implant having a cup-shaped cap component and a pin fixed to its concave inner surface, a pick-up coil is arranged in the latter, each respective terminal of the same being connected to a tissue electrode. One tissue electrode comprises a cap component, the other an electrode provided insulated on the pin or on at least one part of the pin which is electrically insulated from the cap component. By inducing a low-frequency alternating current in the pick-up coil by means of an external coil, this low-frequency alternating current flows from the two tissue electrodes through the femoral head bone provided with the implant, thereby promoting the maintenance of its vitality.

Abstract: Disclosed herein is a sizer for use in cosmetic surgery augmentation procedures, along with methods for using same. The sizer includes an inflatable shell that can be pressurized to assume a shape and size to guide an augmentation procedure, and then deflated for insertion to or removal from the surgical side. The sizer also includes a reinforcing mesh to prevent puncture of the inflatable shell during a surgical procedure.

Abstract: A hip prosthesis has an oblong plate with at one head end a mounting pin provided with a hinge ball, and at the opposite head end a fastening pin for fastening the hip prosthesis in a shaft of a bone. A first part of the plate extends on a first side of the mounting pin. The mounting pin forms an angle ? smaller than 90 degrees with the first part of the plate and the tangent to the fastening pin at the location of the connection between the fastening pin and the first part of the plate forms an angle ? greater than 90 degrees with the first part of the plate. In order to insert the hip prosthesis into a bone in a simple manner, the fastening pin includes a curved shape from the plate onwards in a direction to the first part of the plate.

Abstract: A prosthetic for use in an interphalangeal joint including a body portion and a weave portion. The body portion may be manufactured from a hydrogel material. The body portion includes an pair of stems and an intermediate section located in between the two stems. The intermediate section includes a recess allowing for flexing of the body portion.

Abstract: A medical implant for the expansion and support of a body vessel is formed as elongate struts in a shape of a tube. The struts are plastically deformable at least in sections so that the implant remains permanently expanded in the radial direction transversely to a longitudinal axis of the struts in the expanded state. A course of the expandable element has a plurality of direction changes with respect to the longitudinal axis. The expandable element has a constriction point in the contracted state designed as an intended breaking point for the expandable element. The constriction point breaks upon application of excessive force applied in the radial direction preventing further expansion of the expandable element.

Abstract: Among other things, there are disclosed embodiments of implants for repairing or relieving damage to the distal radioulnar joint. A component for replacing at least part of the ulnar head includes a concave surface for accommodating a convex surface of a component for attachment to the radius, e.g. in the sigmoid notch of the radius.

Abstract: A joint resurfacing prosthetic implant system is disclosed having an anatomically-shaped implant to replace a joint at a pedal digit or finger, including a head having an elliptical bearing surface disposed for engaging the end of an adjacent bone and a seating surface opposite the bearing surface, an elongated stem extending distally from the seating surface, and a flange on the circumference of the device and extending distally from the seating surface. The flange includes one or more portals and a removed section configured to avoid impinging upon a tendon during and after implantation of the prosthetic. A specialized tool is also provided to facilitate the resection of the bone for implantation. The specialized tool includes an elliptical template having a cutting edge and a center insert that is sized and configured to match a reamer used to bore into the bone for insertion of the implant.

Abstract: A cotyle including a metallic insertion acetabular shell having an outer, essentially hemispherical, convex anchoring face formed in such a way as to be anchored in a cotyloid cavity of the pelvis of a patient, and a concave receiving face. The cotyle also includes a fixed definitive articular ceramic insert having an outer face engaging in the concave receiving face of the metallic insertion acetabular shell, and an inner receiving face including a concave, essentially hemispherical, articular surface for allowing the engagement and pivoting of a femoral prosthesis head or a mobile articular insert. The cotyle is packed in its assembled sterile state, with the definitive fixed articular ceramic insert engaged in the metallic insertion acetabular shell having a peripheral receiving structure that can receive means for fixing an impacter for positioning a cotyle and is designed in such a way that the impacter can be fixed to the cotyle in the presence of the definitive fixed articular ceramic insert.

Abstract: A case for modular neck components for hip implants. The case may include indicators based on independent variables associated with physical characteristics of the implant, including leg length, offset, and anteversion. During surgery, the surgeon may be confronted with a need to change a preoperatively-chosen modular neck. For example, the surgeon may desire a change in at least one of the variables, e.g., leg length, offset, and/or anteversion. The case allows the surgeon to quickly and easily select a different modular neck based on an evaluation of one of the variables without requiring reevaluation of the other variables. A method described herein may include preoperative planning in which a template including a grid coordinate system is used, which advantageously provides an intuitive system for the surgeon both preoperatively and during surgery.