Abstract: A system for posture and movement regulation includes at least one body-position sensor unit, at least one arithmetic unit, and at least one output unit for outputting an acoustic signal, and/or at least one output unit for outputting a vibration signal.

Abstract: The present invention provides a micro biosensor for reducing a measurement interference when measuring a target analyte in the biofluid, including: a substrate; a first working electrode configured on the surface, and including a first sensing section; a second working electrode configured on the surface, and including a second sensing section which is configured adjacent to at least one side of the first sensing section; and a chemical reagent covered on at least a portion of the first sensing section for reacting with the target analyte to produce a resultant. When the first working electrode is driven by a first working voltage, the first sensing section measures a physiological signal with respect to the target analyte. When the second working electrode is driven by a second working voltage, the second conductive material can directly consume the interferant so as to continuously reduce the measurement inference of the physiological signal.

Abstract: Disclosed herein are combined devices and methods of manufacturing such combined devices. The combined devices disclosed herein include an analyte sensor including a sensor probe; an infusion set hub including a cannula; and a flexible base. The analyte sensor and infusion set hub are attached to the flexible base such that movement of one of the analyte sensor and the infusion set hub is substantially not transferred to the other one of the analyte sensor and the infusion set hub.

Abstract: Embodiments of the present disclosure identify and alert a clinician to physiological cues thereby aiding the clinician in providing a better fitting of a medical prosthesis. Physiological data of a recipient of a medical prosthesis is analyzed to identify triggers during fitting or other types of adjustments to the prosthesis. A determination is then made as to whether the identified triggers correspond to a feedback event. If the triggers correspond to a feedback event, an alert containing information about the feedback event is generated and displayed or otherwise made available to the clinician.

Abstract: The present disclosure is directed to the first methods and systems for diagnosing a patient being affected by a brain injury from a blast with greater accuracy that previous methods. The methods and system include an automated, non-invasive method for assessing the variance of a patient's ocular motility relative to a matched cohort of unaffected subjects, and using the variance in one or more ocular motility metrics to calculate a score that indicates a likelihood that the patient suffers from a blast brain injury. The score, referred to as a BIS, discriminates between affected an unaffected subjects with a sensitivity of greater than about 85%, a specificity of greater than 75%. The ROCAUC of the BIS is greater than 0.85.

Abstract: A respiratory function testing system includes an air transforming device, a sound reception device and an operation device. The air transforming device is configured to collect exhaled and/or inhaled air for a predetermined period and generate a wide frequency range sound signal according to the collected respired air. The wide frequency range sound signal at least contains an ultrasonic signal. The sound reception device is configured to receive and record the wide frequency range sound signal as an audio file. The operation device is in communication with the sound reception device and is configured to receive and compute the audio file to generate a respiratory function parameter. Besides, the recorded wide frequency range sound signal may be converted into a spectrogram for further applications, and the computation of the audio file can be replaced by analyzing the spectrogram. A respiratory function testing method corresponding to the respiratory function testing system is also provided.

Abstract: Systems and techniques that facilitate background monitoring of eye health are provided. In various embodiments, a system can comprise a sensor component of a device. In various aspects, the sensor component can detect one or more physical characteristics associated with an entity. In various embodiments, the system can further comprise a diagnostic component of the device. In various instances, the diagnostic component can estimate in a background of the device a health condition of an eye of the entity based on the one or more physical characteristics. In various cases, estimating the health condition in the background of the device can facilitate real-time monitoring of the eye health of the entity without interrupting the entity's normal use of the device.

Abstract: A computerized method for detecting a core temperature of a person, the method may include: receiving multiple temperature readings obtained by scanning a temperature sensor across a skin area of a person, the skin area covers at least one blood vessel, to provide multiple temperature readings; the multiple temperature readings include a peak temperature reading; and determining, by a processor, an estimate of the core temperature of the person in response to at least one temperature reading that differs from the peak temperature reading.

Abstract: A fluid control device includes an inlet configured to be placed directly or indirectly in fluid communication with a bodily fluid source and an outlet configured to be placed in fluid communication with a fluid collection device. The fluid control device has a first state in which a negative pressure differential produced from an external source such as the fluid collection device is applied to the fluid control device to draw an initial volume of bodily fluid from the bodily fluid source, through the inlet, and into a sequestration portion of the fluid control device. The fluid control device has a second state in which (1) the sequestration portion sequesters the initial volume, and (2) the negative pressure differential draws a subsequent volume of bodily fluid, being substantially free of contaminants, from the bodily fluid source, through the fluid control device, and into the fluid collection device.

Abstract: A fluid control device includes an inlet configured to be placed directly or indirectly in fluid communication with a bodily fluid source and an outlet configured to be placed in fluid communication with a fluid collection device. The fluid control device has a first state in which a negative pressure differential produced from an external source such as the fluid collection device is applied to the fluid control device to draw an initial volume of bodily fluid from the bodily fluid source, through the inlet, and into a sequestration portion of the fluid control device. The fluid control device has a second state in which (1) the sequestration portion sequesters the initial volume, and (2) the negative pressure differential draws a subsequent volume of bodily fluid, being substantially free of contaminants, from the bodily fluid source, through the fluid control device, and into the fluid collection device.

Abstract: Systems and methods for digital reflex quantization and signature analysis. Movement of a stimulating device invoking a reflex response in an organism is captured as stimuli data. Electromyographic (EMG) of the reflex response is captured as EMG data. Movement resulting from the reflex response of a limb/appendage of the organism is captured as motion data. One or more of the stimuli data, the EMG data, and the motion data are analyzed to determine one or both of a motion signature and an EMG signature defining quantitative evaluation of the reflex response.

Abstract: Systems, methods and graphical user interfaces for visualizing analyte measurements using animation are presented. For instance, a system for continuously monitoring analyte concentration in a physiological fluid includes a sensor, a transmitter, at least one processor and a display. The display is for outputting a graphical user interface. The display is controlled by the at least one processor to display, using the graphical user interface, historical analyte concentration levels and a trend indication animation. The trend indication animation comprises at least one visual element configured by the at least one processor to have a periodic motion between a first position and a second position on the display in one of a plurality of trend directions. The trend direction of the periodic motion between the first and second positions indicates whether the analyte concentration is increasing or decreasing and the rate of change of the analyte concentration level.

Abstract: A flexible, passive pressure sensor includes three LC tank circuits. The first LC tank circuit is a pressure sensing LC tank circuit, having a capacitance that varies in response to changes in environmental pressure. The second and third LC tank circuits are reference LC tank circuits, having capacitances that are relatively constant over changes in environmental pressure. A measurement tool measures the resonant frequencies of the three LC tank circuits and then computes a pressure measurement that accounts for changes in resonant frequencies in the LC tank circuits due to environmental effects and deforming.

Abstract: An intraocular pressure (IOP) sensing system may comprise an intraocular pressure sensing implant to be implanted into the eye of a patient for capturing absolute intraocular pressure measurements and an external device for capturing atmospheric pressure measurements. The intraocular pressure sensing implant may be configured to capture an absolute intraocular pressure measurement at an appointed time, and the external device may be configured to capture a plurality of atmospheric pressure measurements around the appointed time.

Abstract: A method of alerting a user to the existence of an artificially induced neuromuscular response in a subject includes: generating a series of electrical stimuli at a predetermined period with an electrode disposed at a distal end portion of an elongate medical device; detecting a series of mechanomyographic (MMG) responses of the subject using a mechanical sensor, each MMG response indicative of a contraction of a muscle of the subject; determining a degree of statistical confidence that the detected series of MMG responses was artificially induced by the series of electrical stimuli; and outputting, to the user, both an alert that a series of MMG responses has been detected, and the determined degree of statistical confidence that the detected series of MMG responses was artificially induced by the series of electrical stimuli.

Abstract: A catheter and guide wire assembly (10) for measurement of blood pressure in a living body, comprising: a proximal tube (11) having a distal end and a proximal end; a distal tube (12) having a distal end and a proximal end, which is connected to the distal end of the proximal tube (11); a fluid-permeable coil (13) having a distal end and a proximal end, which is connected to the distal end of the distal tube (12); a distal tip (14), in which the distal end of the fluid-permeable coil (13) is secured; and a core wire (16), which is attached in the proximal tube (11) and which extends through a portion of the proximal tube (11), the distal tube (12) and the fluid-permeable coil (13), and is secured in the distal tip (14), wherein the distal end of the proximal tube (11) and the proximal end of the distal tube (12) are connected by a butt joint and wherein the core wire (16) is glued or brazed to the inner wall of the proximal tube (11) at or close to the butt joint.

Abstract: Methods for dynamically evaluating blood flow are provided. The method may include injecting Indocyanine Green (ICG) into the bloodstream of a patient, such that the ICG perfuses into a tissue of the patient. ICG images of the tissue may be recorded and stored, such that a user may select a range of stored ICG images. Data indicative of the selected range of stored ICG images is automatically normalized and background-filtering, and a dynamic representation of the ICG perfusion may be generated as a function of time based on the normalized and filtered data. As such, a clinical decision may be made based on the dynamic representation of the ICG perfusion.

Abstract: A method for identifying and treating a neural pathway associated with chronic pain via nerve stimulation and brain wave monitoring of a mammalian brain is described. The method includes positioning a probe to stimulate a target nerve, wherein the target nerve is suspected of being a source of chronic pain; delivering a first nerve stimulation from the probe to the target nerve, wherein the first nerve stimulation is sufficient to elicit a chronic pain response in the brain; and monitoring for evoked potential activity in the brain as a result of the first nerve stimulation. The method can also include delivering second and third nerve stimulations to confirm the correct identification of the neural pathway and to treat the chronic pain, respectively. A system and apparatus for performing a procedure to identify and treat a nerve that is the source of chronic pain are also described.

Abstract: An apparatus and method for predicting a fertility window include an image capture device and a processor. The fertility window includes a period of increased fecundability for a woman based on optical monitoring of facial features. The image capture device is configured to record images including facial features of a subject. The processor is configured to receive data corresponding to the recorded plural images; determine from the data changes in the facial features; and predict a fertility window based on the determination.

Abstract: System and method for determining breathing rate as biofeedback is provided. First biomarker, second biomarker, third biomarker and fourth biomarker is extracted by computation engine from physiological parameters associated with subject by applying pre-defined set of rules. A first value is computed by feedback unit as a function of second biomarker, third biomarker and fourth biomarker. A correlation between first value and time domain parameter of fourth biomarker and frequency domain parameter of fourth biomarker is determined. First value indicates stress level of subject. Second value is computed by maximizing time domain parameter of fourth biomarker and minimizing frequency domain parameter of fourth biomarker based on correlation. Second value indicates reduced stress level of subject. Biofeedback is transmitted by feedback unit to cue generation unit which represents quantified data determined based on second value. The quantified data is indicative of modified second biomarker.