Patents Examined by David M. Naff
  • Patent number: 7063855
    Abstract: A composition is for feeding aquacultural prey organisms such as Artemia and rotifiers, comprising a lipid component comprising at least 25 wt % of phospholipids and providing a DHA content of at least 30 wt %. The lipid component is preferably derived from marine organisms such as fishmeal, phytoplankton or zoo plankton biomass. The composition is used for providing prey organisms having a high content of highly-unsaturated fatty acids (HUFAs) suitable for aquaculture of fish including halibut, turbot, bass and crustaceans and molluses.
    Type: Grant
    Filed: January 15, 2001
    Date of Patent: June 20, 2006
    Inventors: Baldur Hjaltason, Gudmundur G. Haraldsson, Olafur Halldorsson
  • Patent number: 7063836
    Abstract: The invention includes methods and compositions for treating an animal to inhibit the incidence and growth of E. coli O157:H7 and other pathogenic bacteria. The treatment method comprises administering a therapeutically effective amount of Lactobacillus acidophilus or one or a combination of a number of other probiotic bacteria to an animal. An alternative treatment method comprises administering a therapeutically effective amount of a lactic acid producing bacterium such as Lactobacillus acidophilus in combination with a lactate utilizing bacterium such as Propionibacterium freudenreichii.
    Type: Grant
    Filed: November 6, 2002
    Date of Patent: June 20, 2006
    Inventors: Bryan E. Garner, Douglas R. Ware
  • Patent number: 7060286
    Abstract: The present invention provides an external preparation for skin which contains, as a major ingredient, oleaginous substances extracted from sporoderm-broken spores from Ganoderma lucidum. The spores are preferably being treated with germination activation. The oleaginous substances are preferred to be extracted by a supercritical fluid-carbon dioxide (SCF-CO2) method. The oleaginous substances prepared by SCF-CO2 is transparent and odorless. They also demonstrates effects on skin smoothening, wrinkles reduction, aging defiance, inflammation lessening, pigmentation lightening, and irritation alleviation. The external preparation can be a cosmetic or a therapeutic composition.
    Type: Grant
    Filed: February 13, 2004
    Date of Patent: June 13, 2006
    Inventors: Chee-Keung Chung, Siu-Kan Tong
  • Patent number: 7060478
    Abstract: A process for preparing lysozyme is provided which is characterized by mixing the egg white or its diluted solution with diatomaceous earth, kaolin, zeolite, or the mixtures thereof, and followed by eluting the adsorbed lysozyme with a salt solution. The diatomaceous earth, kaolin, and zeolite can specifically adsorb the lysozyme in egg white, and the adsorbed lysozyme can be easily eluted with a salt solution. According to the process of the present invention, the lysozyme in egg white can be easily and effectively isolated.
    Type: Grant
    Filed: March 12, 2004
    Date of Patent: June 13, 2006
    Inventor: Min-Hsiung Lee
  • Patent number: 7052688
    Abstract: The disclosure is of a combination of lactic acid bacteria comprising: (a) a first component consisting of at least one strain of H2O2-producing lactic acid bacteria; and (b) a second component consisting of at least one strain of arginine-utilizing lactic acid bacteria. The disclosure is also of the use of this combination for making a food supplement, a hygiene product or a pharmaceutical preparation for the prevention and/or treatment of infections and inflammatory conditions caused by bacteria, viruses or fungi, especially in the mouth, vagina, urethra, nose, eyes and ears.
    Type: Grant
    Filed: December 21, 2001
    Date of Patent: May 30, 2006
    Assignee: VSL Pharmaceuticals, Inc.
    Inventor: Claudio De Simone
  • Patent number: 7041504
    Abstract: Compositions of matter are described which contain restricted cancer cells. When so restricted, the cells produce an unexpectedly high amount of material which suppresses cancer cell proliferation. The phenomenon crosses cancer type and species lines. Processes for making these compositions, and their use, are also described.
    Type: Grant
    Filed: December 12, 2000
    Date of Patent: May 9, 2006
    Assignee: The Rogosin Institute
    Inventors: Shirin Asina, Kanti Jain, Albert L. Rubin, Barry Smith, Kurt Stenzel
  • Patent number: 7037642
    Abstract: Methods and devices are provided for reducing the concentration of low molecular weight compounds in a biological composition containing cells while substantially maintaining a desired biological activity of the biological composition. The device comprises highly porous adsorbent particles, and the adsorbent particles are immobilized by an inert matrix.
    Type: Grant
    Filed: October 5, 2001
    Date of Patent: May 2, 2006
    Assignee: Cerus Corporation
    Inventor: Derek J. Hei
  • Patent number: 7033621
    Abstract: Processes for the production of isoflavones are described wherein plant material from plants of the genus leguminosae are contacted with water, an enzyme which cleaves isoflavone glycosides to the aglucone form and a C2-C10 organic solvent, so as to form a combination, incubating the combination for a time sufficient to allow isoflavones of the aglucone form to partition into the organic solvent component, and thereafter recovering isoflavones from the organic solvent component.
    Type: Grant
    Filed: April 11, 2000
    Date of Patent: April 25, 2006
    Assignee: Novogen, Inc.
    Inventors: Graham E. Kelly, Jiu Li Huang, Mark G. Deacon-Shaw, Mark A. Waring
  • Patent number: 7033586
    Abstract: The present invention provides a Paecilomyces tenuipes T1 FERM BP-7861, insecticidal compositions, methods and uses. The insecticidal compositions comprise an insecticidally effective amount of Paecilomyces tenuipes T1 FERM BP-7861. The methods comprise applying Paecilomyces tenuipes T1 FERM BP-7861 to at least one location selected from a pest, a habitat of the pest and a plant. The uses are uses of Paecilomyces tenuipes T1 FERM BP-7861 for controlling a pest.
    Type: Grant
    Filed: September 26, 2002
    Date of Patent: April 25, 2006
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Susumu Shimizu, Shinji Isayama, Eiji Nitta
  • Patent number: 7033584
    Abstract: A process is provided for growing microflora of the order Thraustochytriales such as Thraustochytrium, Schizochytrium, and mixtures thereof, in fermentation medium containing non-chloride containing sodium salts, in particular sodium sulfate. In a preferred embodiment, the process produce, microflora having a cell aggregate size useful for the production of food products for use in aquaculture. Further provided is a food product which includes Thraustochytrium, Schizochytrium, and mixture thereof, and a component selected from flaxseed, reapedeed, soybean and avocado meal. Such a food product includes a balance of long chain and short chain omega-3 highly unsaturated fatty acids. A method for increasing omega-3 highly unsaturated fatty acid content of eggs by feeding a feed to poultry. The feed contains the microorganisms of the order Thraustochytriales having a omega-3 highly unsaturated fatty acid content of more than 6.7 percent of total cell dry weight.
    Type: Grant
    Filed: December 4, 2000
    Date of Patent: April 25, 2006
    Assignee: Omegatech, Inc.
    Inventor: William R. Barclay
  • Patent number: 7029884
    Abstract: A carrier for microorganism incubation of a diffusion type in which microelements and inorganic nutrient salts which are useful in proliferation of microorganism are included in a porous material is provided. This carrier may be employed in a bioreactor for treatment of waste water where high activity and high density of the microorganism is desired.
    Type: Grant
    Filed: April 21, 2003
    Date of Patent: April 18, 2006
    Assignee: Japan Science and Technology Corporation
    Inventor: Takaaki Maekawa
  • Patent number: 7029669
    Abstract: Novel microorganisms of the family Lactobacillaceae, particularly microorganisms of the gnus Lactobacillus, that are useful in preventing or treating diarrhoea are provided. The microorganism can be utilized for the preparation of an ingestable support and to a composition containing same. The microorganism Lactobacillus paracasei CNCM I-2116 can be included.
    Type: Grant
    Filed: March 2, 2000
    Date of Patent: April 18, 2006
    Assignee: Nestec S. A.
    Inventors: Roberto Reniero, Harald Bruessow, Florence Rochat, Thierry Von Der Weid, Stephanie Blum-Speriesen
  • Patent number: 7029689
    Abstract: The present invention is directed to devices for repair, replacement or augmentation of soft tissues in an organism. The devices comprise cellular compositions comprising cells and preferably, structural proteins such as collagen or elastin. The devices can also be used in methods for testing the effects of agents on soft tissues.
    Type: Grant
    Filed: May 10, 2002
    Date of Patent: April 18, 2006
    Assignee: Georgia Tech Research Corporation
    Inventors: Joseph D. Berglund, Robert M. Nerem, Athanassios Sambanis
  • Patent number: 7025974
    Abstract: The invention describes compositions and methods for inhibiting microbial infections associated with the use of sanitary products, such as diapers, bandages, sanitary napkins, tampons and the like. The invention comprises providing for use a sanitary product containing an effective amount of a viable non-pathogenic lactic-acid bacteria, such as Bacillus coagulans, or an extracellular product thereof, useful for inhibiting growth of parasites and pathogens on the epithelial tissue in contact with the sanitary product during use of the product. The invention also provides for enhancing biodegradation of sanitary products after use and disposal. Also described are methods using the product and systems containing the compositions.
    Type: Grant
    Filed: April 5, 2004
    Date of Patent: April 11, 2006
    Assignee: Ganeden Biotech Incorporated
    Inventors: Sean Farmer, Andrew R. Lefkowitz
  • Patent number: 7026146
    Abstract: A method for maintaining the viability and subsequent activity of microorganisms utilized in a variety of environments to promote biodecontamination of surfaces. One application involves the decontamination of concrete surfaces. Encapsulation of microbial influenced degradation (MID) microorganisms has shown that MID activity is effectively maintained under passive conditions, that is, without manual addition of moisture or nutrients, for an extended period of time.
    Type: Grant
    Filed: August 12, 2002
    Date of Patent: April 11, 2006
    Assignee: Battelle Energy Alliance, LLC
    Inventors: Robert D. Rogers, Melinda A. Hamilton, Lee O. Nelson, Jennifer Benson, Martin J. Green, Timothy N. Milner
  • Patent number: 7022309
    Abstract: Targeting molecules are provided for use in delivering imaging agents to epithelial tissue. The targeting molecule comprises a polypeptide that forms a closed covalent loop, contains at least three peptide domains having ?-sheet character, each of the domains being separated by domains lacking ?-sheet character. The targeting molecule specifically binds to a basolateral factor attached to a basolateral domain of an epithelial cell surface causing internalization of a linked imaging agent into the cells. The polypeptide or imaging agent may be linked to a peptide amino acid sequence that directs delivery of the imaging agent to a carcinoma cell, a nucleus, or an endoplasmic reticulum.
    Type: Grant
    Filed: February 5, 2002
    Date of Patent: April 4, 2006
    Assignee: Biolex Newco I, Inc.
    Inventors: Andrew C. Hiatt, Mich B. Hein, John H. Fitchen
  • Patent number: 7022512
    Abstract: Disclosed is a process for growing the microflora Thraustochytrium, Schizochytrium, and mixtures thereof, which includes the growing of the microflora in fermentation medium containing non-chloride containing sodium salts, in particular sodium sulfate. In a preferred embodiment of the present invention, the process produces microflora having a cell aggregate size useful for the production of food products for use in aquaculture. Further disclosed is a food product which includes Thraustochytrium, Schizochytrium, and mixtures thereof, and a component selected from flaxseed, rapeseed, soybean and avocado meal. Such a food product includes a balance of long chain and short chain omega-3 highly unsaturated fatty acids.
    Type: Grant
    Filed: February 27, 2004
    Date of Patent: April 4, 2006
    Assignee: Martek Biosciences Corporation
    Inventor: William R. Barclay
  • Patent number: 7022347
    Abstract: The restorative and grafting material for reconstruction of hard tissue defects and the fabrication method of the same are provided. In particular, the restorative and grafting material of this invention is produced by the steps of cleansing, decoloration (bleaching), burning, and pulverization of collected animal teeth.
    Type: Grant
    Filed: November 19, 2003
    Date of Patent: April 4, 2006
    Inventors: Su-Gwan Kim, Young Guyn Kim
  • Patent number: 7022522
    Abstract: A polymer scaffold is provided comprising an extensively interconnected macroporous network. The polymer scaffold embodies macropores having a diameter in a range of 0.5-3.5 mm, and preferably in a range of about 1.0-2.0 mm. The polymer scaffold is prepared using a novel process which advantageously combines the techniques of particulate leaching and phase inversion to render a process that provides amplified means by which to control the morphology of the resulting polymer scaffold. The polymer scaffold has utility in the area of tissue engineering, particularly as a scaffold for both in vitro and in vivo cell growth. The polymer scaffold may be produced using pure polymer or alternatively a composite material may be formed consisting of a macroporous polymer scaffold and osteoclast-resorbable calcium phosphate particles with a binding agent binding the calcium phosphate particles to the polymer scaffold.
    Type: Grant
    Filed: April 30, 2002
    Date of Patent: April 4, 2006
    Inventors: Limin Guan, Chantal E. Holy, Molly S. Shoichet, John E. Davies
  • Patent number: 7022509
    Abstract: A method for removing a gas from a site comprising placing cells having gas vesicles under conditions that induce the cells to float to a surface of an aqueous medium, harvesting the cells from the surface of the medium, lysing the cells, separating the gas vesicles from the lysed cells, crosslinking the gas vesicles with a crosslinking agent, loading a gas with a lowered partial pressure for the compound to be removed into the gas vesicles, and placing the gas vesicles such that the gas compound is removed from the site. Harvesting gas-vesicle-containing cells is achieved by placing the cells under conditions that induce the cells to rise to the surface of an aqueous medium—such as darkness, exponential growth stage, flocculation, or dissolved gas flotation—then collecting the cells from the surface of the medium. Gas vesicles are isolated by lysing the cells and separating the gas vesicles from the lysate. Once the gas vesicles are isolated, they can be modified, such as by crosslinking with glutaraldehyde.
    Type: Grant
    Filed: May 10, 2002
    Date of Patent: April 4, 2006
    Assignee: The University of Akron
    Inventors: Lu-Kwang Ju, Anand Sundararajan, Sunil Kashyap