Abstract: Human prostatic and placental transglutaminases are identified and cloned. The human transglutaminases herein are useful for, inter alia, therapeutic wound repair, closure of skin grafts, stabilizing food preparations, and markers for identifying agents which act as agonists or antagonists of cellular apoptosis.
Type:
Grant
Filed:
December 30, 1992
Date of Patent:
May 7, 1996
Assignee:
Zymogenetics, Inc.
Inventors:
Patrick J. O'Hara, Francis J. Grant, Paul O. Sheppard