Abstract: The invention relates to screening of patients to determine the possible presence of Kawasaki Disease. The screening involves assaying for levels of V.beta.2 or V.beta.8.1 by immunoassay, or for the mRNA expressing either of these V.beta. elements. The polymerase chain reaction is one way the mRNA level can be determined. Once the levels in the patient are determined, they are compared to normal levels. An increase is indicative of possible Kawasaki Disease.
Type:
Grant
Filed:
January 11, 1993
Date of Patent:
February 15, 1994
Assignee:
National Jewish Center for Immunology and Respiratory Medicine
Inventors:
Donald Y. M. Leung, Brian Kotzin, Jun Abe
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