Abstract: A tunable dye laser has been found particularly suited to selective photothermolysis. A longer pulse duration which makes the system suitable for a wider range of applications is obtained by modifying the laser to generate a spatially noncoherent beam. The optical system at each end of the laser cell, which may include a lens or spherical mirror, refocuses the aperture of the dye cell near to itself so that substantially all light emanating from the dye cell is returned to the dye cell until the light passes through one of the optic systems as a noncoherent laser beam. A tunable intracavity element tunes the laser across the gain curve of the dye solution. The pulse duration of the laser beam can be selected from a range of durations up to about one millisecond.

Abstract: Apparatus and method for extracting cataract tissue in which the cataract is first softened by focusing laser radiation thereon and subsequently a tube inserted through an incision to a position adjacent the cataract. An irrigating liquid is supplied through one portion of the tube and the liquid and cataract fragments removed via an aspirating opening adjacent the tube opening. Fragments which do not readily pass through the aspirating opening are dislodged by vibration or broken up by a paddle like member pivotally mounted adjacent the aspirating opening to engage the fragment and apply a force to break up the same.

Abstract: Disclosed herein is an automatic allergy testing system. The system includes an electrode capable of testing up to eight different allergies and an associated electronic unit. The electrode includes apparatus to transcutaneously deliver an allergen to the patient without puncturing the patient's skin. The electrode also includes a temperature sensor for sensing the skin temperature in the area surrounding the delivery of the allergen. Electronic apparatus is provided for processing the sensed temperature and storing data related thereto for subsequent print out to an output device. The allergy testing system is controlled so that periodic temperature readings are made at thrity second intervals over approximately a fifteen minute testing span. The data can be printed out in a graphic format to allow the physician to easily and quickly make more accurate diagnosis.

Abstract: A wrist-mounted pulse rate and body temperature monitor has means for storing upper and lower emergency pulse rates and body temperatures by means of which an emergency medical situation is defined. When the monitor detects an emergency medical situation, an emergency signal is generated on standard emergency locator frequencies to alert search and rescue services. Means for automatically setting the upper and lower safe thresholds is provided. The device is particularly suited for use by individuals in remote areas where either the health of the individual or the environment create a higher risk to the survival of the individual.

Abstract: Disclosed herein is an electrode for performing a plurality of allergy tests on a patient undergoing tests. The allergy electrode consists of a plurality of individual testing electrodes and a single common electrode. Each of the testing electrodes includes allergen delivery apparatus and a temperature sensor. The allergen is contained in a removable allergen impregnated pad. If a dry allergen is used, it may be hydrolized with a drop of distilled water prior to application. A small electric charge charges a charge plate on one side of the allergen pad and a common ring on the electrodes is grounded in circuit with the charging plate, thereby causing electric field to transfer the allergen through the pores of the skin. The area surrounding the allergen delivery area is sensed for temperature by a thin film temperature sensor and a rigid temperature conducted base.

Abstract: There is disclosed herein a system for providing control of multiple functions needed to perform eye surgery. A microprocessor based system controls a vacuum generation system using venturis and linear valves and a pneumatic system for driving vitrectomy probes and pneumatic scissors in either a variable frequency, multicut mode or a proportional cut mode where the cutting pressure is proportional to the position of a foot operated position sensor. The frequency of the vitrectomy probe cutting action can also be controlled and the level of vacuum can be controlled from a foot operated position sensor which can also be used to turn on or off a fragmentation device. The footswitch can also be used to turn irrigation fluid on or off, and the flow rate can be controlled from a control on the front panel. By making a certain foot motion in any certain aspiration modes, reflux of the aspiration line can be controlled.

Abstract: Device and method are disclosed for effecting application of a therapeutic agent. A removable programmable element is used to control operation of a delivery unit, which unit delivers the therapeutic agent to the patient. The programmable element is programmed, while removed from the delivery unit, by a computer that is operationally independent of the delivery unit to insure the integrity of subsequent delivery of the therapeutic agent to the patient by the delivery unit. The delivery unit requires no microprocessor and can include a plurality of channels for effecting independent delivery of therapeutic agents in each channel under the control of the programmable element. The programmable element is programmed with respect to available protocol informaton, including patient history, needs and tolerances, as well as therapeutic agent parameters, to thereby establish a flow profile that is customized for a particular patient during each moment of each day.

Abstract: The invention contemplates removal of epithelium-layer material from the anterior surface of the cornea, as a step preparatory to sculpting laser surgery, wherein controlled ultraviolet irradiation of the cornea is operative to surgically ablate corneal tissue within an epithelium-free area which is in the optically used central region of the cornea. For corrective sculpting recurvatures involving relatively small diopter change, the sculpture proceeds via selectively distributed ultraviolet radiation to the epithelium-free area, with penetration essentially only or at least predominantly in the tissue of Bowman's membrane, thus achieving the corrected-curvature profile essentially only or predominantly in the tissue of Bowman's membrane.

Abstract: The present invention involves an electrical muscle stimulator for knee stabilization in a leg having inadequate neurological and muscular control to obtain normalization of locomotion and includes a power source, muscle stimulation electrodes, a control unit with manual on/off and with two control on/off switches. One of these switches is responsive to a heel ground contact determining means and the other to a knee angle determining means. Stimulation can only be effected when both the knees are in contact with some weight pressure and the knee angle measuring means shows the knees bent to or beyond a preset angle. As soon as one of these two conditions are not met, stimulation ceases.

Abstract: A nasal cannula harness is provided which includes a pair of sheet members in facing relation and holding the distal end portions of a pair of narine tubes in position for insertion into the nares of a patient. The nasal cannula harness may be made by folding a molded sheet member and securing the sections of the folded member together with the distal portions of the narine tubes between the sections and with portions extending outwardly for insertion into the nares of a patient.

Abstract: There is disclosed herein a system for providing control of multiple functions needed to perform eye surgery. A microprocessor based system controls a vacuum generation system using venturis and linear valves and a pneumatic system for driving vitrectomy probes and pneumatic scissors in either a variable frequency, multicut mode or a proportional cut mode where the cutting pressure is proportional to the position of a foot operated position sensor. The frequency of the vitrectomy probe cutting action can also be controlled and the level of vacuum can be controlled from a foot operated position sensor which can also be used to turn on or off a fragmentation device. The footswitch can also be used to turn irrigation fluid on or off, and the flow rate can be controlled from a control on the front panel. By making a certain foot motion in any certain aspiration modes, reflux of the aspiration line can be controlled.

Abstract: An improved laser catheter system includes a flexible catheter tube having proximate and distal ends. The distal end, which is intended for inserting into a patient's artery, is axially split into at least two segments. Optical waveguides extend the length of the catheter tube and terminate at the distal end, with at least one waveguide secured to each of the spreadable segments. A mechanism is provided for spreading the segments while the catheter is implaced in the patient. Conveniently, a balloon catheter may be used by inserting it into the lumen of the laser catheter so that the balloon tip lies within the spreadable segments. By then inflating the balloon, the spreadable segments are spread apart as desired.

Abstract: A process and apparatus for ablating atherosclerotic or tumorous tissues is disclosed. Optical fibers direct low power light energy at a section of tissue to be ablated to cause the section to fluoresce. The fluorescence pattern is analyzed to determine whether the fluorescence frequency spectrum is representative of normal or abnormal tissue. A source of high power ultraviolet laser energy directed through an optical fiber at the section of tissue is fired only when the fluorometric analysis indicates that it is directed at abnormal tissue.

Abstract: For suppressing cardiovascular artifact from a respiration signal derived from a patient's transthoracic impedance, an adaptive filtering device determines the patient's heart rate, converts the respiration signal from an analog to digital representation at a rate proportional to the heart rate, and then filters the digital respiration signal such that that portion of the respiration signal having a frequency content at or above the heart rate is most greatly attenuated.

Abstract: An apparatus and method for distinguishing between different types of apneic episodes. The method includes measuring a new index, TCD/VT, and measuring the phase relation between the abdominal and rib cage contributions to total respiration volume. The episode is classified as central, obstructive or mixed based on the value of TCD/VT and the phase relation.

Abstract: An improved instrument for obtaining tissue samples for biopsies is adapted to permit accurate samples to be taken with one-hand. The instrument includes a housing which fits into the palm of the physician's hand and has a guide tube projecting from the forward end which the physician guides to a point from which a sample is required. A spring-loaded cannula is telescoped within the guide tube and a notched sampling stylet is telescoped within the cannula. The tips of the cannula and stylet project slightly from the distal end of the guide tube. An arming slide is provided which is moved forward by the physician's thumb, advancing the stylet into the tissue and cocking the spring-loaded cannula. The physician's thumb then operates a spring release trigger causing the cannula to snap forward, cutting the tissue sample in the stylet notch. The instrument is then withdrawn from the tissue.

Abstract: The invention contemplates removal of epithelium-layer material from the anterior surface of the cornea, as a step preparatory to laser surgery, wherein controlled ultraviolet irradiation of the cornea is operative to surgically ablate corneal tissue within an epithelium-free area which is in the optically used central region of the cornea; the control is such (1) as first to effect essentially uniform-depth removal of Bowman's membrane to the extent of exposing only stroma tissue within said central region, and then (2) to so selectively distribute the ultraviolet radiation to then-exposed stroma tissue as to effect in stroma tissue a predetermined sculpted corrective-curvature change in the optically used region. Other important pre-surgury and post-surgery procedural steps are disclosed, for greater assurance of a predictable curvature change through the sculpting laser surgery.

Abstract: The invention contemplates removal of epithelium-layer material from the anterior surface of the cornea, as a step preparatory to laser surgery, wherein controlled ultraviolet irradiation of the cornea is operative to surgically ablate corneal tissue within an epithelium-free area which is in the optically used central region of the cornea; the control is such as to effect a predetermined sculpted corrective-curvature change in the optically used region. Other important pre-surgery and post-surgery procedural steps are disclosed, for greater assurance of a predictable curvature change through the sculpting laser surgery.

Abstract: A device for iontophoresis including an electric source, a pulse generator, a working electrode, and a counter electrode is described. This device has a circuit for discharging the charges accumulated in said electrodes during each intermission period of therapeutic pulses generated by said pulse generator (i.e., a circuit for effecting the depolarization between the above-mentioned both electrodes during each intermission period of therapeutic pulses).This device can be directly and very easily applied to the human skin, without causing undesirable irritation in the skin, especially without causing burns and rubefaction in the skin.

Abstract: Equipment to erase the mesh pattern caused by the arrangement of the optical fibers in an endoscope which uses the optical fiber bundle as an image transferring means. This equipment erases the mesh pattern without decreasing the resolution by providing optical low pass filters to cut off the spatial frequency component higher than the resolution which is specified by the arrangement of the optical fibers on both sides of the image transferring means.