Abstract: Provided herein is a bridging device including, in some embodiments, a piece of tubing including a securement loop, a first connector at a first end of the piece of tubing, and a second connector at a second end of the piece of tubing. Also provided herein is a male external catheter (“MEC”) kit including, in some embodiments, an MEC; a drainage bag for the MEC; and the bridging device for fluidly connecting the MEC to the drainage bag. The securement loop of the piece of tubing is configured for securing the bridging device in a securement device optionally included in the MEC kit. The first connector is configured to connect to the MEC. The second connector is configured to connect to the drainage bag for the MEC. Methods for making and using the foregoing bridging device and MEC kit are also provided.

Abstract: A multi-lumen arthroscopy cannula (MLAC) is described which may be used to contain and manage joint irrigation fluid as a means of improving the state of arthroscopic surgery. The MLAC includes an arrangement of components within a cannula housing. An internal passage (central lumen) through which surgical instruments may be inserted into the body includes a series of components which greatly reduce the leakage path of fluid through the central lumen while enabling manipulation of surgical instruments during arthroscopic procedures. A dual-tapered diaphragm seal grips the instruments as it is manipulated to prevent leakage. This works in concert with the consecutively placed multi-leaflet valves, which act to prevent internal leakage and maintain pressure within the surgical cavity. Unique features of this cannula, aside from the multiple valves and dual-tapered diaphragm seal, include bilateral lumens which provide infusion and withdrawal of irrigation inside the joint capsule.

Abstract: This disclosure relates generally to treatment programs utilizing expansion elements, such as those associated with occlusion and therapeutic agent delivery devices, systems, and methods. In some more specific examples, treatment programs include expansion-contraction cycles at a pre-selected frequency profile configured to treat a particular condition, such as calcification of an arterial conduit, for example.

Abstract: An apparatus and methods for tissue restoration are provided. The apparatus may include a catheter shaft extending from a proximal end to a distal tip, the catheter shaft defining lumens including an inflation lumen and a light fiber lumen, a coated balloon positioned on a translucent distal segment of the catheter shaft proximal to the distal tip in fluid communication with the inflation lumen, the coated distal balloon comprising a translucent material and a coated material on an outer surface of the coated balloon, and a light fiber positioned in the catheter shaft in the light fiber lumen and extending through the translucent distal segment.

Abstract: Sinusitis and other disorders of the ear, nose and throat are diagnosed and/or treated using minimally invasive approaches with flexible or rigid instruments. Various methods and devices are used for remodeling or changing the shape, size or configuration of a sinus ostium or duct or other anatomical structure in the ear, nose or throat; implanting a device, cells or tissues; removing matter from the ear, nose or throat; delivering diagnostic or therapeutic substances or performing other diagnostic or therapeutic procedures. Introducing devices (e.g., guide catheters, tubes, guidewires, elongate probes, other elongate members) may be used to facilitate insertion of working devices (e.g. catheters e.g. balloon catheters, guidewires, tissue cutting or remodeling devices, devices for implanting elements like stents, electrosurgical devices, energy emitting devices, devices for delivering diagnostic or therapeutic agents, substance delivery implants, scopes etc.

Abstract: A roller clamp assembly for adjusting the fluid flow rate in a connector tube of an infusion set is provided. The roller clamp assembly includes a housing to receive the connector tube, a plate slideably engaged with the housing and configured to rapidly compress the connector tube to provide a coarse fluid flow adjustment, and a roller wheel moveable engaged with the housing and configured to provide a gradual fluid flow adjustment. The plate may be a slide plate received by grooves in an exterior wall of the housing and that moves orthogonally to the connector tube, or the plate may be a shim plate that moves along an interior wall of the housing in parallel to the connector tube. Infusion sets and methods of adjusting fluid flow rates are also provided.

Abstract: Provided is a smart contact lens for non-invasive drug delivery including a platform configured to be worn on an eye, a reservoir installed within the platform, and having a receiving part in which a drug is received, to provide the eye with the drug, an electrode for iontophoresis installed in the reservoir to make iontophoresis work, to provide the eye with the drug from the reservoir, and an activation chip electrically connected to the electrode for iontophoresis to activate iontophoresis.

Abstract: A pharmaceutical product including a housing that defines a cavity, wherein the cavity stores a pharmaceutical material, and wherein the housing comprises a material configured to dissolve based on contact with a fluid, an ingestible device to encode information in a current signature, wherein the ingestible device is positioned within the housing, and a protective material that encompasses the ingestible device. The ingestible device may be attached to a flexible component, wherein the flexible component is configured to releasably secure the ingestible device within the housing.

Abstract: A persistent perfusion sheath assembly can be used for the passage of an intravascular medical device while maintain a flow passage in the vessel. The sheath assembly passes through an arteriotomy and can include a first lumen configured for the passage of a medical device, a second lumen configured to allow a flow of fluid from a location in the blood vessel upstream of the arteriotomy to a location downstream of the arteriotomy. The sheath assembly can further include a stylet, a sleeve or an additional sheath configured to selectively open and close the flow of blood between upstream and downstream of the arteriotomy. The sheath assembly can further include a closure device distal of the arteriotomy, the closure device configured to control blood flow through the arteriotomy.

Abstract: A thrombectomy system comprising an aspiration catheter having an aspiration lumen and a high pressure irrigation lumen, the aspiration catheter having a proximal end and a distal, and a control box fluidly connected to the aspiration catheter and configured to synchronously provide irrigation and vacuum through the aspiration catheter.

Abstract: Intravascular catheters that include a handle assembly with first and second handle actuators, where the actuators are adapted to separately control inner and outer catheter shafts in at least one of axial displacement, deflection, or rotation. The catheters may also include a medical tool secured to the outer shaft.

Abstract: A matter elimination catheter includes a catheter body extending from a catheter proximal portion to a catheter distal portion. The catheter body includes an infusion lumen, an aspiration lumen fluidly isolated from the infusion lumen, and a septum interposed between the infusion and aspiration lumens. A drive shaft is within the infusion lumen and is configured to provide rotation near the catheter distal portion. A guide wire lumen is within the drive shaft, and the infusion lumen, the drive shaft and the guide wire lumen are fluidly separated from the aspiration lumen with the septum. In one example, fluid bearings are formed between one or more of the catheter body and drive shaft or the drive shaft and a guide wire or guide wire liner when supplied with infusion fluid through the infusion lumen.

Abstract: The invention relates to a cannulation robot for the automated affixing of a cannula to a patient. The cannulation robot comprises a fixing apparatus for affixing the cannula to the patient by means of an adhesive carrier. The cannulation robot comprises a positioning device designed to position a cannula holder of the cannula to an area of the patient's skin. The cannulation robot comprises an actuator device for a guide means, wherein the guide means is designed to guide the adhesive carrier to said skin area. The actuator device is designed to activate the guide means and thereby move the adhesive carrier by means of the guide means toward the skin area, wherein the adhesive carrier contacts the skin area as a result of the movement and adheres to same as well as is disposed such that it is connected to the cannula at least after being adhered.

Abstract: A catheter securement device with integrated intra-luminal electro-conduction, and external tamper sensitivity, for tamper or movement detection. The catheter securement device accordingly can detect movement or tampering of an inserted catheter, which will allow a healthcare provider to take action to prevent movement or removal of the catheter from a patient.

Abstract: Some embodiments relate to a luer connector comprising a housing having a hollow bore therethrough, a first end, and a second end, a male luer tip supported by the housing configured to rotate with respect to the housing, the luer tip having a first open end and a passageway through the luer tip in fluid communication with the first open end, and a substantially rigid internal member extending into the passageway of the luer tip toward the first open end of the luer tip. In some embodiments, at least one of the luer tip and the internal member can be axially moveable between a first closed position and a second open position relative to the other of the luer tip and the internal member. Further, the luer tip and the internal member can cooperate such that rotation of the luer tip in a first direction relative to the housing increases an axial displacement between the first open end of the luer tip and an end portion of the internal member.

Abstract: Techniques for aligning a medical instrument for percutaneous access to a location within the human anatomy can include determining an orientation of the medical instrument, determining a target location within the human anatomy, and determining a target trajectory for percutaneous access of the target location. Further, the techniques can include causing display of an interface that includes an instrument-alignment element indicative of an alignment of the orientation of the medical instrument to the target trajectory.

Abstract: An automatic injector dispenses a predetermined dose of medicament without a user having to manually force the needle into an injection site. The automatic injector includes a needle cover having a locked retracted position with respect to the injector housing prior to a medicament dispensing operation. The needle cover is operative to engage an injection site prior to a medicament dispensing operation.

Abstract: The present disclosure relates to relates to systems and methods for on-demand delivery of a therapeutic agent from an eye mounted device. Particularly, aspects of the present invention are directed to a method of delivering a therapeutic agent, the method including receiving, at a controller of a therapeutic agent release and delivery device, a first command signal for delivery of a therapeutic agent based on a dosing time window. Upon receipt of the first command signal, the controller determines whether one or more compliance conditions are satisfied. When the one or more conditions are satisfied, the controller initiate a release and delivery protocol that commands a signal generator to generate and send a second command signal causing a capacitor or one or more circuits to deliver an actuation signal causing one or more therapeutic agent delivery mechanisms to open and release the therapeutic agent from one or more reservoirs.

Abstract: A device for cleaning medical implements is disclosed, in particular a device for cleaning vascular or other fluid access sites. The device includes a cap having an opening to receive an access site. The cap may be used in the following manner: A healthcare worker may, with gloved hands, open the cap packaging and place the cap over the port of a medical implement to be cleaned. The healthcare worker may wipe the site by either applying a turning motion or by simply pushing the cap onto the port. The cap could then remain secured in place by threads other mechanisms. A cap in place on a medical implement may be a positive indication that a desired site of the medical implement is clean. The cap may include a disinfecting substance.

Abstract: A position determination device and system for determining and registering an injection location of a liquid drug administered on a body part of a user. The position determination device and system includes a position determination element configured to provide a position signal representing a current location of the position determination device, and one or more processing units configured to derive data representing an actual injection location based on the user in response to a current location being determined by the position determination unit. The position determination device can be further configured for determining a dosage activity performed by a liquid drug administration device based on obtaining at least one vibration signal from a vibration determination element.