Patents Examined by Deborah C. Carr
  • Patent number: 5098910
    Abstract: The invention relates to combinations of angiotensin-converting enzyme inhibitors with calcium antagonists, processes for their preparation and their use as medicaments.
    Type: Grant
    Filed: May 30, 1989
    Date of Patent: March 24, 1992
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Reinhard Becker, Rainer Henning, Wolfgang Ruger, Volker Teetz, Hansjorg Urbach
  • Patent number: 5095129
    Abstract: New 19,11.beta.-bridged steroids of the general formula I ##STR1## where R.sup.1 stands for a methyl or ethyl radical,R.sup.2 for a hydrogen or chlorine atom or a C.sub.1 -C.sub.4 -alkyl radical,B and G, which are the same or different, respectively for a hydrogen atom, a C.sub.1 -C.sub.4 -alkyl radical or, together, for a second bond between the carbon atoms 6 and 7,B and R.sup.2 together for a methylene or an ethylene group,Z for the radical of a pentagonal or hexagonal ring, which is possibly substituted and possibly unsaturated,V stands for a possibly substituted carbocyclic or heterocyclic aryl radical,the ring A for ##STR2## M and N together meaning a second bond or M a hydrogen atom and N a hydroxy group,X means an oxygen atom, two hydrogen atoms or a hydroxyimino grouping N.about.OH,R.sup.3 and D, which are the same or different, respectively a hydrogen atom, a nitrile radical or a C.sub.1 -C.sub.4 -alkyl radical or, together, a methylene or ethylene group,E a hydrogen atom or a C.sub.1 -C.sub.
    Type: Grant
    Filed: December 9, 1988
    Date of Patent: March 10, 1992
    Assignee: Schering Aktiengesellschaft
    Inventors: Eckhard Ottow, Rudolf Wiechert, Gunter Neef, Sybille Beier, Walter Elger, David A. Henderson