Patents Examined by Delia Raminez
  • Overcoming DAPA aminotransferase bottlenecks in biotin vitamers biosynthesis
    Patent number: 6737256
    Abstract: A method is disclosed for the increased production of biotin and the biotin precursor dethiobiotin using a bacterium that produces a lysine-utilizing DAPA aminotransferase. This method involves the use of a bacterium that is either grown in the presence of lysine or deregulated for lysine biosynthesis.
    Type: Grant
    Filed: July 14, 1997
    Date of Patent: May 18, 2004
    Assignee: Roche Vitamins Inc.
    Inventors: Scott W. Van Arsdell, R. Rogers Yocum, John B. Perkins, Janice G. Pero