Patents Examined by Denise Bernstein
  • Monoclonal antibodies reactive with normal and oncogenic forms of the ras p21 protein
    Patent number: 5081230
    Abstract: Monoclonal antibodies reactive with normal and oncogenic forms of the ras p21 protein. The antibodies are secreted by hybridomas obtained by immunizing mice with the Ha ras p21 protein containing the arginine mutation at position 12 of the protein. The antibodies and immunoreactive fragments thereof of useful for detection, diagnosis, quantitation, staging and classification of normal and activated ras p21s in normal tissues, malignant and premalignant lesions.
    Type: Grant
    Filed: July 8, 1987
    Date of Patent: January 14, 1992
    Assignee: E. I. DuPont DeNemours and Company
    Inventor: Walter P. Carney