Patents Examined by Dennis White
  • Patent number: 10458963
    Abstract: A field testing device is provided for quantitating psychoactive components of marijuana such as THC in biological fluids such as saliva. Such a device may include an HPTLC plate for separating interferents from THC and may also include fluorometric components for quantitating THC. The device may include a microprocessor adapted to relate fluorescent intensity to analyte concentration through one or more calibration curves. Devices may optionally include microfluidics for carrying out HPTLC on biological samples including sample reservoirs, reagent reservoirs, micro-pumps, mixers, and the like.
    Type: Grant
    Filed: June 8, 2017
    Date of Patent: October 29, 2019
    Inventor: Kathleen Stitzlein
  • Patent number: 10458939
    Abstract: As a receptor layer, a film of a composite material of a base material such as a polymer and particles that adsorb an analyte is used. When the present invention is applied to a surface stress sensor or the like, the Young's modulus of the receptor layer, which significantly affects detection sensitivity, can be preset with a high degree of freedom, by independently selecting particles that adsorb a desired analyte and a base material that disperses said particles therein.
    Type: Grant
    Filed: February 25, 2016
    Date of Patent: October 29, 2019
    Assignee: NATIONAL INSTITUTE FOR MATERIALS SCIENCE
    Inventors: Kota Shiba, Genki Yoshikawa, Gaku Imamura
  • Patent number: 10451629
    Abstract: A component measuring device includes a calibration member that is slidably disposed in an insertion hole of a chip attachment unit and a biasing member that biases the calibration member toward an insertion port. The calibration member is held by the biasing member at a position where the calibration member blocks the introduction port and a lead-out port and where light from a light emitter is applied to the calibration member when a measuring chip is not inserted in the insertion hole, and slides to a side opposite to the insertion port along with insertion of the measuring chip into the insertion hole so that light from the light emitter is applied to the measuring chip.
    Type: Grant
    Filed: September 26, 2016
    Date of Patent: October 22, 2019
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventor: Masao Takinami
  • Patent number: 10444184
    Abstract: An assembly is provided for interfacing with a microfluidic chip having at least one microscopic channel configured to receive a liquid sample for analysis. The assembly includes a chip carrier, an electronics module, an optical module, and a mechanical module. The chip carrier includes a base and a cover defining a cavity to receive the microfluidic chip. The electronics module includes a signal generator which applies at least one electrokinetic signal electrode(s) of the chip. The optical module includes an excitation radiation source which causes excitation radiation to impinge on the sample, and an emission radiation detector which detects radiation emitted from the sample. The mechanical module includes a chip-carrier receiving structure, relatable with respect to the optical module for focus and at least one degree of translational freedom.
    Type: Grant
    Filed: June 30, 2016
    Date of Patent: October 15, 2019
    Assignee: International Business Machines Corporation
    Inventors: Jaione T. Azpiroz, Emmanuel Delamarche, Claudius Feger, Ricardo L. Ohta, Mathias B. Steiner, Yuksel Temiz
  • Patent number: 10436738
    Abstract: The present disclosure concerns a membrane for a sensor, such as an opto-chemical or electrochemical sensor, including a polymer layer, for example, one featuring pores or openings, that is permeable to a measuring fluid and/or an analyte contained in the measuring fluid, with a surface designed to be in contact with a measuring fluid, wherein the surface is designed such that, at least in a moist condition of the polymer layer obtained by moistening the surface, a contact angle of a water drop applied to the surface is less than 50°, including less than 30°, and including less than 10°.
    Type: Grant
    Filed: December 20, 2016
    Date of Patent: October 8, 2019
    Assignee: Endress+Hauser Conducta GmbH+Co. KG
    Inventors: Andreas Löbbert, Alexander Hörig
  • Patent number: 10422576
    Abstract: A gas sensor includes a plurality of detectors discolored by reacting with different predetermined target gases, such that the gas sensor independently measures the amount of each target gas. A refrigerator for deciding a type and state of target food contained in a container by sensing a color change of a gas sensor mounted to the container including the target food, and a method for controlling the gas sensor are disclosed. The gas sensor for detecting a plurality of target gases includes a base and a plurality of detectors provided at the base. The detectors respectively detect different target gases, and each detector is discolored by reacting with each predetermined target gas.
    Type: Grant
    Filed: April 2, 2015
    Date of Patent: September 24, 2019
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Jang Pyo Park, Youn Joo Song, Yong Won Jeong, Hyun Joo Jung
  • Patent number: 10422728
    Abstract: A specimen extraction kit includes a flexible tubular container configured to contain an extraction liquid, two holding portions opposed to each other and arranged at opposite sides of the tubular container, a coupling portion that couples the opposing holding portions, and a bending rib arranged on each of the opposing holding portions and configured to bend the tubular container and an extraction subject.
    Type: Grant
    Filed: September 26, 2014
    Date of Patent: September 24, 2019
    Assignee: Denka Seiken Co.
    Inventors: Masashi Suzaki, Makoto Fukasawa, Yoshiaki Hirayama, Kazuhiro Akiishi
  • Patent number: 10416050
    Abstract: A liquid sample drying device, dried sample test piece and the preparation method for the dried sample test piece are provided. The liquid sample drying device includes two substrates, at least one spacer and a clamping member. Each of the two substrates includes a surface. The two surfaces face each other. The at least one spacer is located in between the substrates so as to form a sample region between the surfaces for receiving a liquid sample. The clamping member touches the two substrates so as to temporarily clamp and fix the two substrates and the at least one spacer together.
    Type: Grant
    Filed: September 10, 2014
    Date of Patent: September 17, 2019
    Assignee: Materials Analysis Technology, Inc.
    Inventors: Lin-Ai Tai, Yu-Ching Chen, Chih-Jung Sun, Pin Chang
  • Patent number: 10406518
    Abstract: The invention relates to a device and to a method for storing and transporting a bodily fluid sample, comprising a support element (2), which forms a main body. At least one sorption element (3), which has a defined filling volume and is suitable for receiving a drop of the bodily fluid, and an overflow reservoir (4), which is adjacent to the sorption element (3) and which receives the bodily fluid from the sorption element (3) as soon as the filling volume of the sorption element (3) is filled, are fastened to the support element. The technical solution according to the invention is characterized in that at least one predetermined breaking point (5) is provided, which is designed in such a way that the sorption element (3) can be manually detached from the support element (1) and/or from the overflow reservoir (4) without an auxiliary tool.
    Type: Grant
    Filed: June 11, 2014
    Date of Patent: September 10, 2019
    Assignee: EUROIMMUN MEDIZINISCHE LABORDIAGNOSTIKA AG
    Inventors: Victor Herbst, Birgit Nagel
  • Patent number: 10408828
    Abstract: It is an object of the present invention to provide improved methods and compositions for manufacture and use of lateral flow test devices. In particular, the present invention provides a molding method which provides one or more features in the housing base configured to retain the test strip within the base. These features are provided as undercuts in the housing base. The test strip is configured as a bibulous lateral flow material disposed on a substantially non-compressible base layer, and the base layer is positioned within the undercut in order to retain the test strip in the housing base. Optionally, one or more features in the housing base which create the undercut are configured to engage the bibulous lateral flow material by compression and/or friction, thereby increasing the ability of the base to maintaining the test strip in its proper position within the device.
    Type: Grant
    Filed: February 25, 2014
    Date of Patent: September 10, 2019
    Assignee: Astute Medical, Inc.
    Inventors: Joseph Anderberg, John Van Bosch
  • Patent number: 10393738
    Abstract: The present application discloses a multi-well cuvette for integrating the reaction between a sample and a reagent with the detection of a specific analyte included therein, and the multi-well cuvette comprises: a reaction chamber part having a sample and a reagent placed therein; and a detection part for detecting the reaction between the sample and the reagent, wherein the reaction chamber part comprises: an extraction member standby chamber in which a member for dividing or distributing the sample is on standby; a sample filling chamber; and a reagent filling chamber which is filled with the reagent, and in which the reaction with the sample is carried out, wherein the detection part comprises: a chromatography analysis means for a reactive product between the sample and the reagent; and a detection chamber for accommodating the same.
    Type: Grant
    Filed: November 11, 2014
    Date of Patent: August 27, 2019
    Assignee: Boditech Med Inc.
    Inventors: Byeong-Chul Kim, Bong-Sok Moon, Won-Hee Lee, Chan-Young Jeon
  • Patent number: 10384205
    Abstract: The invention provides a collection and detection integrated device with a mis-assembling prevention structure. The collection and detection integrated device with a mis-assembling prevention structure comprises: a detector; a test strip holder, detachably arranged in the detector; a collector, detachably contained in the detector; a faeces collection piece and a cushion block, configured to detachably seal the collector; and a piercing part, arranged on a bottom surface of the detector and configured to pierce the collector, wherein the test strip holder and the collector are contained in the detector side by side, the collector is located between the test strip holder and the detector, a first outer side face of the collector is adjacent to an inner side wall of the detector, a second outer side face of the collector is adjacent to the test strip holder, and the first outer side face and the second outer side face of the collector are asymmetric structurally.
    Type: Grant
    Filed: May 19, 2016
    Date of Patent: August 20, 2019
    Assignee: W.H.P.M. BIORESEARCH AND TECHNOLOGY CO., LTD.
    Inventors: John Wan, Qinghai Xia, Panpan Hou, Jie Liu
  • Patent number: 10386347
    Abstract: A printed gas sensor, comprising a metalloporphyrin dye, has first and second modes, and a nanoporous carrier material comprising a plurality of particles measuring less than 5 ?m; the particles have a plurality of pores, the pore size in the range 5-50 nm, wherein the metalloporphyrin dye is bound to the nanoporous carrier material. The disclosure further comprises a method of preparing a gas sensing composition for detection of food status and a digital expiry date device system, which comprises a packaging material with inner and outer surfaces; a first transponder disposed on the inner surface and a second transponder disposed on the outer surface. A sensor portion is electrically connected to the first transponder for detecting food status and communicating the status to the second transponder. The sensor portion comprises a metalloporphyrin dye which configures an impedance change upon binding with an gaseous analyte, and a printed numerical array.
    Type: Grant
    Filed: February 24, 2015
    Date of Patent: August 20, 2019
    Assignee: INNOSCENTIA AB
    Inventor: Martin Andreas Olsson
  • Patent number: 10379055
    Abstract: Gas detector tube templates are described. Gas detector tubes may be used to determine the concentration of target gases in a sampled gas either visually or electronically. Gas detector tubes for visual reading have the length-of-stain demarcations printed or etched on the transparent tube. However, the demarcations may interfere with electronic reading of gas detector tubes. Embodiments of a gas detector tube template may be used to accurately and reliably read gas detector tubes that do not have concentration demarcations printed on the tube in the working area adjacent to the chemical reagent. The gas detector tube template may have a gas detector tube holder capable of reversibly receiving a gas detector tube and two scale card holders. The gas detector tube template could have a left and right scale holder hingedly connected to the gas detector tube holder. The gas detector tube template may be used with scale cards capable of being, reversibly received in the scale rockets.
    Type: Grant
    Filed: March 7, 2016
    Date of Patent: August 13, 2019
    Assignee: Nextteq LLC
    Inventor: Bryan I. Truex
  • Patent number: 10379044
    Abstract: An analysis chip contains a test reagent retention member and a sensing member. The test reagent retention member has a housing part for housing the sensing member, and an engaging part for engaging the sensing member within the housing part. The sensing member is secured in the housing part by the engaging part, in such a way as to have a certain area of mobility in relation to the housing part.
    Type: Grant
    Filed: January 19, 2016
    Date of Patent: August 13, 2019
    Assignee: KONICA MINOLTA, INC.
    Inventors: Hiroshi Umetsu, Yoshihiro Okumura
  • Patent number: 10371609
    Abstract: A device is described that overlays a first fluid, such as blood or a cellular suspension onto a base material, such as a density gradient. In some embodiments, the fluid layering device includes a cylindrical reservoir, a fluid barrier, a coupling extension, a plunger, and an exhaust vent. The fluid layering device can be coupled through its coupling extension to an open end of a container, such as a conical centrifuge tube, including the density gradient. Once attached, the plunger may be lowered to a position above the surface of the density gradient. A first fluid may flow from the reservoir into the conical tube across the plunger, so that a suitable overlay is formed without substantially disturbing a surface of the density gradient. The plunger may be buoyed upward by the first fluid during operation, providing a constant regulation of flow throughout overlaying, regardless of the care and skill of the user.
    Type: Grant
    Filed: August 9, 2012
    Date of Patent: August 6, 2019
    Inventor: Jae Go Kwon
  • Patent number: 10371606
    Abstract: Bodily fluid sample collection systems, devices, and method are provided. The sample is collected at a first location and subjected to a first sample processing step. The sample may be shipped to a second location and subjected to a second sample processing step that does not introduce contaminants into a plasma portion of the sample formed from the first processing step. The sample may also be mixed with other material(s) in the collection device.
    Type: Grant
    Filed: October 11, 2016
    Date of Patent: August 6, 2019
    Assignee: Theraos IP Company, LLC
    Inventors: Elizabeth A. Holmes, Clarissa Lui, Michael Chen, Daniel Young
  • Patent number: 10371697
    Abstract: The present invention pertains to the field of manufacture of diagnostic test elements. Specifically, the invention relates to a diagnostic test element for determining an analyte comprised in a body fluid sample, said test element comprising at least one test field with at least one detection layer and at least one separation layer, wherein said at least one separation layer comprises dispersed SiO2 in an amount of about 1.0 to 1.6 g/m2. The invention also relates to a coating composition being capable of forming a separation layer on a diagnostic test element of the present invention described above. Moreover, provided is a method for the manufacture of the diagnostic test element as well as the use of the diagnostic test element for determining the amount of an analyte, preferably, glucose, in a sample of a subject.
    Type: Grant
    Filed: July 22, 2016
    Date of Patent: August 6, 2019
    Assignee: Roche Diabetes Care, Inc.
    Inventors: Alexander Ibach, Yilmaz Isgoeren
  • Patent number: 10371700
    Abstract: An in-vitro diagnostic includes a housing, a storage, and a blocking agent. The housing houses a liquid including a test substance included in a sample extracted from a subject. The storage stores a substance that specifically reacts with the test substance. The blocking agent is placed to separate the container and the storage.
    Type: Grant
    Filed: June 1, 2017
    Date of Patent: August 6, 2019
    Assignee: Canon Medical Systems Corporation
    Inventors: Asuka Hirano, Shoichi Kanayama, Ichiro Tono
  • Patent number: 10364411
    Abstract: A microfabricated device having at least one gas-entrapping feature formed therein in a configuration that entraps air bubbles upon wetting the feature with a solvent or solution is described. The device includes a sacrificial residue in contact with the gas-entrapping feature, the dissolution of which guides the wetting of the gas-entrapping feature.
    Type: Grant
    Filed: June 1, 2018
    Date of Patent: July 30, 2019
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Nancy Allbritton, Yuli Wang, Christopher Sims