Abstract: New peptides are disclosed which have biological activity of the same type as known calcitonins and which have an alanine in position 19 instead of the natural leucine or phenylalanine found in those positions. Also resin peptides are disclosed which may be converted to peptides having such biological activity; and processes for producing said resin peptides and said calcitonin peptides.
Type:
Grant
Filed:
May 6, 1987
Date of Patent:
April 25, 1989
Assignee:
Rorer Pharmaceutical Corporation
Inventors:
Ronald C. Orlowski, Glenn L. Stahl, Robert L. Colescott