Abstract: Provided is the novel class of platinum compounds shown in formula (I), and their use as pharmaceutical agents, especially for treating cancer alone or in combination and for preventing cancer. The described novel platinum compounds have been shown, through experimentation, to have superior in vivo antitumor effects, significantly better than the clinical drug carboplatin, and to have significantly improved the aqueous solubility of platinum-based drugs, and can be made into lyophilized powder or injectable solution, resolving the defect of inconvenient clinical use. In view of the foregoing, the disclosed class of platinum compounds has good prospects for clinical application.

Abstract: The present invention relates to a novel polycyclic compound employed in an organic layer of an organoelectro luminescent device, wherein the organoelectro luminescent device employing the compound according to the present invention has remarkably improved luminous efficiency. According to the present invention, it is possible to implement a highly efficient organoelectro luminescent device that can be effectively applied to various display devices.

Abstract: A method for producing a diphosphine monoxide represented by a general formula (2), including: allowing a diphosphine represented by a general formula (1) to react with water in the presence of a metal catalyst, an oxidizing agent, and a base to selectively oxidize the diphosphine. In the general formulas (1) and (2), R1, R2, R3, R4, and Y are the same as defined in the description.

Abstract: A method of producing a monomer composition including a polymerizable group-containing phosphoric acid compound is provided. The method includes a step of allowing a polymerizable group-containing alcohol compound, which is a compound not containing a urethane bond, to react with phosphorus pentoxide in the presence of a urethane compound, thereby obtaining a monomer composition including a polymerizable group-containing phosphoric acid compound.

Abstract: The present invention relates to a method of preparing a nano-sized, iron-based catalyst, the method comprising: mixing a solution containing an iron salt with a surfactant to form a mixture; adding a basic salt solution comprising a salt of element selected from the group consisting of: alkali metals, alkaline earth metals, transition metals of groups 3 to 7 and 9 to 11 of the Periodic Table of Elements, lanthanides, and combinations of elements thereof, to the mixture to form a precipitate; and calcining said precipitate to form the iron-based catalyst, said iron-based catalyst at least partially comprising said element of said basic salt. The present invention also relates to a nano-sized, iron-based catalyst prepared by the above method and a process for the production of light olefins using the nano-sized, iron-based catalyst.

Abstract: The present invention provides a method for obtaining high-quality products. The present invention relates to a purification apparatus that purifies crystals, the purification apparatus including: a hydraulic wash column that includes a discharging port for a crystal-containing circulation slurry and a return port for a circulation liquid containing a melt of discharged crystals; a pipe that feeds a crystal-containing slurry to the hydraulic wash column; a filter that filters the crystal-containing slurry in the hydraulic wash column; a pipe that is connected to the filter and discharges a mother liquor; and a unit that melts crystals in a circulation slurry discharged through the discharging port, wherein a distance between a lower end of the filter and an average bottom surface level of the hydraulic wash column is 1000 mm or more.

Abstract: Disclosed herein is a method for the preparation of diarylmethane dyes and triarylmethane dyes, such as Isosulfan Blue, using electrochemistry. Further disclosed is Isosulfan Blue prepared from a process employing electrochemistry, compositions comprising the same, and use of the prepared Isosulfan Blue as an imaging agent.

Abstract: A preparation method of a sulfur-containing biphenylsulfur-containing biphenyl compound shown by the general formula (I) has a reaction formula as follows: Each substituent in the formula is defined in the description. In the method, halogeno benzene shown by the general formula (II) generates a coupling reaction in a catalytic system composed of a nickel compound and at least one ligand under the combined action of metallic zinc to obtain the sulfur-containing biphenyl compound shown by the general formula (I).

Abstract: A method for preparing bio-based 1,4-butanediol (BDO) is provided, including: mixing succinic acid from a bio-based source and an alcohol compound to obtain a mixture, and subjecting the mixture to esterification to obtain an oligomer polyester; subjecting the oligomer polyester to hydrogenation reduction in the presence of a catalyst to obtain a 1,4-BDO crude product; and purifying the 1,4-BDO crude product to obtain the bio-based 1,4-BDO.

Abstract: The invention relates to a process for preparing ?,?-ethylenically unsaturated carboxylic acids by two-stage catalytic gas phase oxidation of alkenes, in which a gas stream (1) containing at least one alkene, in a first reactor (A) in the presence of oxygen, is subjected to a first catalytic oxidation reaction over a first catalyst (K1) in the form of a multimetal oxide of molybdenum to obtain a gas stream (2) containing at least one ?,?-ethylenically unsaturated aldehyde, the gas stream (2) containing the at least one ?,?-ethylenically unsaturated aldehyde is guided through a connecting conduit (V) into a second reactor (B) and the gas stream (2) containing the at least one ?,?-ethylenically unsaturated aldehyde, in the second reactor (B) in the presence of oxygen, is subjected to a second catalytic oxidation reaction over a second catalyst (K2) to obtain a gas stream (3) containing at least one ?,?-ethylenically unsaturated carboxylic acid.

Abstract: A method for producing fluorenone including a pretreatment step of heating fluorene in the presence of a lower aliphatic carboxylic acid, a bromine compound, and a metal catalyst, and an oxidation step of continuously supplying fluorene and oxygen to perform an oxidation reaction, in the order indicated.

Abstract: A method for producing (meth)acrolein by vapor-phase catalytic oxidation of propylene or isobutylene in a multitubular reactor including a plurality of reaction tubes, the reaction tubes each including a reaction zone filled with a catalyst including molybdenum oxide and a cooling zone filled with an inert substance, wherein a temperature of a heat medium that flows outside the cooling zone is lower than a temperature of a heat medium that flows outside the reaction zone, and wherein the inert substance includes an inert substance having a major-axis length that is equal to or more than 1.7 times a major-axis length of the catalyst. A method for producing (meth)acrylic acid in which (meth)acrolein thus produced is converted to (meth)acrylic acid by vapor-phase catalytic oxidation.

Abstract: The present invention relates to an iron complex having the general formula (I) or a pharmaceutically acceptable salt thereof. The present invention also relates to a pharmaceutical composition formulated for oral and/or parenteral administration, preferably intravenous, said pharmaceutical composition preferably being formulated as an aqueous solution comprising said complex or salt. The present invention further relates to said complex or a salt thereof or said pharmaceutical composition for use as a contrast agent for magnetic resonance imaging (MRI), as well as a method and a kit for in situ preparation of said complex or salt and said pharmaceutical composition.

Abstract: A catalyst for production of carboxylic acid ester, containing: catalyst metal particles; and a support supporting the catalyst metal particles, wherein the catalyst has a hollow particle ratio of 40% or less.

Abstract: Provided is a biodegradation accelerator for accelerating the biodegradation of resins, etc. in the ocean. This marine-biodegradation accelerator comprises a compound including anions of one or more kinds including an anion having six or more carbon atoms and three or more oxygen atoms and a metal cation having a valence of two or higher, the anions and the cation being bonded by ionic bonding. A group of particles of the compound forms a contact angle of 30° or larger 30 seconds after a waterdrop is dropped thereonto.

Abstract: The present invention provides, in part cystine cationic lipid compounds of formula A, and sub-formulas thereof: or a pharmaceutically acceptable salt thereof. The compounds provided herein can be useful for delivery and expression of mRNA and encoded protein, e.g., as a component of liposomal delivery vehicle, and accordingly can be useful for treating various diseases, disorders and conditions, such as those associated with deficiency of one or more proteins.

Abstract: The present invention relates to a catalytic material for the preparation of one or more of 4,4?-methylenedianiline, 2,2?-methylenedianiline, 2,4?-methylenedianiline, and oligomers of two or more thereof, the catalytic material comprising an oxidic support, wherein the oxidic support comprises an element EOS1 selected from the group consisting of Ti, Zr, Al, Si, and mixtures of two or more thereof, and further comprising a supported material supported on the oxidic support, wherein the supported material comprises an element ESM1 selected from the group consisting of Ti, Zr, V, Nb, Ta, Mo, W, Ge, Sn, Sc, Y, La, Ce, Nd, Pr, Hf, Cr, Fe, Co, Ni, Cu, Zn, Pb and mixtures of two or more thereof. Further, the present invention relates in particular to a process for the preparation of a catalytic material and to a process for the preparation of one or more of 4,4?-methylenedianiline, 2,2?-methylenedianiline, 2,4?-methylenedianiline and oligomers of two or more thereof.

Abstract: Compositions and methods are provided for reducing, inhibiting, or preventing corrosion of a surface, the polyamine compounds corresponding to the structure of Formula 1 or 2, or a salt thereof: wherein X1 is —C(O)R9 or —[C(R10R11)]p—C(R12)(X2)—R13; X2 is —OH or —NH2; R1 and R4 are independently hydrogen, alkyl, or —[C(R10R11)]p—C(R12)(X2)—R13; R2, R3, R5, R6, R7, R8, R10, R11, and R12 are independently hydrogen or alkyl; R9 and R13 are independently C7 to C30 alkyl or alkenyl; m and o are integers from 1 to 10; n is an integer from 1 to 6; and p is an integer from 1 to 10; wherein X2 is —OH or —NH2; R21, R22, R23, R24, R25, R26, and R28 are independently hydrogen or alkyl; R27 is C10 to C30 alkyl or alkenyl; m and o are integers from 1 to 10; n is an integer from 1 to 6; and q is an integer from 0 to 10.

Abstract: A method for preparing 2-hydroxy-4-methylthiobutyric acid (HMTBA) or 2-hydroxy-4-methylselenobutyric acid (HMSeBA) by catalytic conversion of 2-hydroxy-4-methylthiobutyronitrile or 2-hydroxy-4-methylselenobutyronitrile, respectively, where said conversion is carried out in the presence of water and at least one weak acid and one catalyst comprising at least one of alumina, titanium dioxide and zirconia.

Abstract: An object of the present invention is to provide a catalyst capable of improving the selectivity of unsaturated aldehydes and unsaturated carboxylic acids, and a catalyst containing molybdenum, antimony, bismuth, and iron, wherein an atom ratio of the antimony to the molybdenum on a surface of the catalyst is greater than an atom ratio of the antimony to the molybdenum in the entire catalyst is provided.