Patents Examined by Derek Rhoades
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Patent number: 12698258Abstract: The present invention provides, in part cystine cationic lipid compounds of formula A, and sub-formulas thereof: or a pharmaceutically acceptable salt thereof. The compounds provided herein can be useful for delivery and expression of mRNA and encoded protein, e.g., as a component of liposomal delivery vehicle, and accordingly can be useful for treating various diseases, disorders and conditions, such as those associated with deficiency of one or more proteins.Type: GrantFiled: April 17, 2020Date of Patent: August 4, 2026Assignee: TRANSLATE BIO, INC.Inventors: Shrirang Karve, Saswata Karmakar, Frank DeRosa
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Patent number: 12698253Abstract: The present invention relates to a catalytic material for the preparation of one or more of 4,4?-methylenedianiline, 2,2?-methylenedianiline, 2,4?-methylenedianiline, and oligomers of two or more thereof, the catalytic material comprising an oxidic support, wherein the oxidic support comprises an element EOS1 selected from the group consisting of Ti, Zr, Al, Si, and mixtures of two or more thereof, and further comprising a supported material supported on the oxidic support, wherein the supported material comprises an element ESM1 selected from the group consisting of Ti, Zr, V, Nb, Ta, Mo, W, Ge, Sn, Sc, Y, La, Ce, Nd, Pr, Hf, Cr, Fe, Co, Ni, Cu, Zn, Pb and mixtures of two or more thereof. Further, the present invention relates in particular to a process for the preparation of a catalytic material and to a process for the preparation of one or more of 4,4?-methylenedianiline, 2,2?-methylenedianiline, 2,4?-methylenedianiline and oligomers of two or more thereof.Type: GrantFiled: December 11, 2020Date of Patent: August 4, 2026Assignee: BASF SEInventors: Andrei-Nicolae Parvulescu, Alvaro Gordillo Bolonio, Trees Maria De Baerdemaeker, Ulrich Mueller, Dirk de Vos, Ka Yan Cheung
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Patent number: 12698256Abstract: Compositions and methods are provided for reducing, inhibiting, or preventing corrosion of a surface, the polyamine compounds corresponding to the structure of Formula 1 or 2, or a salt thereof: wherein X1 is —C(O)R9 or —[C(R10R11)]p—C(R12)(X2)—R13; X2 is —OH or —NH2; R1 and R4 are independently hydrogen, alkyl, or —[C(R10R11)]p—C(R12)(X2)—R13; R2, R3, R5, R6, R7, R8, R10, R11, and R12 are independently hydrogen or alkyl; R9 and R13 are independently C7 to C30 alkyl or alkenyl; m and o are integers from 1 to 10; n is an integer from 1 to 6; and p is an integer from 1 to 10; wherein X2 is —OH or —NH2; R21, R22, R23, R24, R25, R26, and R28 are independently hydrogen or alkyl; R27 is C10 to C30 alkyl or alkenyl; m and o are integers from 1 to 10; n is an integer from 1 to 6; and q is an integer from 0 to 10.Type: GrantFiled: August 5, 2022Date of Patent: August 4, 2026Assignee: Ecolab USA Inc.Inventors: Oussama Zenasni, John Nathan Scholz, Philip Andrew Thornthwaite, Maria DeJesus Marquez, Ana Ferrer Carrera, Ashish Dhawan
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Patent number: 12692226Abstract: A method for preparing 2-hydroxy-4-methylthiobutyric acid (HMTBA) or 2-hydroxy-4-methylselenobutyric acid (HMSeBA) by catalytic conversion of 2-hydroxy-4-methylthiobutyronitrile or 2-hydroxy-4-methylselenobutyronitrile, respectively, where said conversion is carried out in the presence of water and at least one weak acid and one catalyst comprising at least one of alumina, titanium dioxide and zirconia.Type: GrantFiled: October 20, 2021Date of Patent: July 28, 2026Assignees: ADISSEO FRANCE S.A.S., CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, ECOLE CENTRALE DE LILLE, UNIVERSITE CLAUDE BERNARD LYON 1Inventors: Félix Taulou, Didier Morvan, Virginie Belliere-Baca, Dorothée Laurenti
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Patent number: 12691438Abstract: An object of the present invention is to provide a catalyst capable of improving the selectivity of unsaturated aldehydes and unsaturated carboxylic acids, and a catalyst containing molybdenum, antimony, bismuth, and iron, wherein an atom ratio of the antimony to the molybdenum on a surface of the catalyst is greater than an atom ratio of the antimony to the molybdenum in the entire catalyst is provided.Type: GrantFiled: August 10, 2022Date of Patent: July 28, 2026Assignee: Mitsubishi Chemical CorporationInventors: Kensuke Nishiki, Takuro Watanabe, Tetsufumi Yamaguchi
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Patent number: 12692215Abstract: A process for producing functionalized organic molecules having 1 to 3 carbon atoms. The method includes the step of contacting carbon dioxide as the only gas, or a gas mixture that includes carbon dioxide and methane, in the presence of water, with a catalyst that includes permanently polarized hydroxyapatite.Type: GrantFiled: April 27, 2021Date of Patent: July 28, 2026Assignee: Universitat Politécnica de CatalunyaInventors: Pau Turón Dols, Vanesa Sanz Beltrán, Anna Maria Rodríguez Rivero, Carlos Enrique Alemán Llansó, Jordi Puiggalí Bellalta, Guillem Revilla-López, Jordi Sans
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Patent number: 12686830Abstract: Embodiments of the present disclosure are directed processes to produce a low-color esterified oil soluble polyalkylene glycol, the process comprising forming a reaction mixture including a low viscosity oil soluble polyalkylene glycol and an excess amount of valeric acid, where the reaction mixture is formed in the presence of a catalytic amount of ortho-phosphoric acid catalyst to yield an organic phase including the low-color esterified oil soluble polyalkylene glycol.Type: GrantFiled: August 8, 2019Date of Patent: July 21, 2026Assignee: Dow Global Technologies LLCInventors: Edward Daugs, Martin R. Greaves, Yaokun Han
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Patent number: 12686694Abstract: The present invention relates to a method of extracting at least one selected from carbonic acid, aliphatic acid, aliphatic acid ester and aliphatic alcohol from an aqueous medium, the method comprising the steps: (a) contacting the carbonic acid, aliphatic acid, aliphatic acid ester and/or aliphatic alcohol in the aqueous medium with an extracting medium containing at least one alkyl-phosphine oxide for a time sufficient to extract the carbonic acid, aliphatic acid, aliphatic acid ester and/or aliphatic alcohol from the aqueous medium into the extracting medium, and (b) separating the extracting medium with the extracted carbonic acid, aliphatic acid, aliphatic acid ester and/or aliphatic alcohol from the aqueous medium, characterized in, that the at least one alkyl-phosphine oxide contains at least two different alkyl radicals per alkyl-phosphine oxide molecule and the aqueous medium in (a) contains a microorganism, preferably a living microorganism, producing the carbonic acid, aliphatic acid, aliphaticType: GrantFiled: July 23, 2020Date of Patent: July 21, 2026Assignee: Evonik Operations GmbHInventors: Thomas Haas, Christian Richter
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Patent number: 12678771Abstract: A carbon dioxide (CO2) hydrogenation catalyst and a method of its preparation. The CO2 hydrogenation catalyst includes an alkali-metal enriched bauxite residue including calcium carbonate (CaCO3), iron(III) oxide (Fe2O3), iron(III) oxyhydroxide (FeO(OH)), aluminum hydroxide (Al(OH)3), sodalite, muscovite, and Na5Al2CSi3O15. The CO2 hydrogenation catalyst further includes 1 weight percent (wt. %) to 10 wt. % potassium based on a total weight of the CO2 hydrogenation catalyst by inductively coupled plasma optical emission spectroscopy (ICP-OES). The CO2 hydrogenation catalyst is used in a method of hydrogenating carbon dioxide to produce olefins.Type: GrantFiled: April 24, 2025Date of Patent: July 14, 2026Assignee: KING FAHD UNIVERSITY OF PETROLEUM AND MINERALSInventors: M. Nasiruzzaman Shaikh, Mahbuba Aktary, Atif Alzahrani, Mohamed Ahmed Yahya Sanhoob
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Patent number: 12668559Abstract: The present invention relates to a process of hydrogenating an alkyne selectively to an alkene by hydrogen using a hydrogenation catalyst which is palladium supported on a carrier in the presence of an additive mixture of an organic phosphorus compound (AP) and an organic sulphur compound (AS).Type: GrantFiled: May 26, 2020Date of Patent: June 30, 2026Assignee: DSM IP ASSETS B.V.Inventors: Jonathan Alan Medlock, Lise Malika Molinari
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Patent number: 12662444Abstract: A process for manufacturing aliphatic amines and nitriles by using the Fischer Tropsch synthesis (FTS), in the production of chain-lengthened hydrocarbons from CO and H2 and their terminal nitrogen functionalization using ammonia. The method can include activating a catalyst with a feed gas, wherein the feed gas comprises H2/CO mixtures; providing a temperature between 180° C. and 300° C. under a pressure between 1 bar to 25 bar; wherein the nitrogenates include at least one aliphatic amine and/or nitrile; and setting or adjusting the H2/CO ratio to selectively synthesize amines and/or nitriles over other nitrogen containing compounds.Type: GrantFiled: April 30, 2021Date of Patent: June 23, 2026Assignee: Washington State UniversityInventors: Norbert Kruse, Hafsa Karroum, Viacheslav Iablokov
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Patent number: 12662495Abstract: The present disclosure relates to a silicon precursor compound, a method of preparing the silicon precursor compound, a silicon-containing film-forming precursor composition including the silicon precursor compound, and a method of forming a silicon-containing film using the precursor compound.Type: GrantFiled: July 29, 2022Date of Patent: June 23, 2026Assignee: UP CHEMICAL CO., LTD.Inventors: Jin Sik Kim, Byung Kwan Kim, Jun Hwan Choi, Da Som Yu
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Patent number: 12660456Abstract: The present invention relates to a display device comprising a plurality of OLED pixels comprising at least two OLED pixels, the OLED pixels comprising an anode, a cathode, and a stack of organic layers, wherein the stack of organic layers is arranged between and in contact with the cathode and the anode, and comprises a first electron transport layer, a first hole transport layer, and a first light emitting layer provided between the first hole transport layer and the first electron transport layer, and a driving circuit configured to separately driving the pixels of the plurality of OLED pixels, wherein, for the plurality of OLED pixels, the first hole transport layer is provided in the stack of organic layers as a common hole transport layer shared by the plurality of OLED pixels, and the first hole transport layer comprises (i) at least one first hole transport matrix compound consisting of covalently bound atoms and (ii) at least one electrical p-dopant selected from metal salts and from electricallType: GrantFiled: November 4, 2021Date of Patent: June 16, 2026Assignee: Novaled GmbHInventors: Ulrich Heggemann, Markus Hummert
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Patent number: 12649711Abstract: The present invention discloses a newly high-efficiency method for co-production of carboxylic acid and ?-caprolactone based on the aerobic oxidation, that is, under the developed catalytic system, the aldehyde is oxidized to corresponding carboxylic acid while cyclohexanone is oxidized to ?-caprolactone, realizes the co-production of carboxylic acid and ?-caprolactone. The salient features of this method include the use of cheap and readily available substrates, mild reaction conditions, environmentally friendly, and easy operation. It can realize the co-production of carboxylic acid and high value-added ?-caprolactone.Type: GrantFiled: July 21, 2020Date of Patent: June 9, 2026Assignee: ZHEJIANG UNIVERSITYInventors: Shengming Ma, Jinxian Liu
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Patent number: 12649710Abstract: A process for the continuous production of either acrolein or acrylic acid as the target product from propene comprising a catalyzed gas phase partial oxidation of propene to yield a product gas containing the target product, transferring the target product in a separating zone from the product gas into the liquid phase and conducting out of the separating zone a stream of residual gas the major portion of which is returned into the partial oxidation and the remaining portion of said stream is purged from the process as off-gas from which synthesis gas can be produced or which can be added to synthesis gas produced otherwise.Type: GrantFiled: July 14, 2020Date of Patent: June 9, 2026Assignee: BASF SEInventors: Kazuhiko Amakawa, Lukas Schulz, Michael Bender, Klaus Joachim Mueller-Engel, Christian Walsdorff, Signe Unverricht
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Patent number: 12637419Abstract: Process for separating anhydrous methanesulfonic acid from a reaction mixture comprising methanesulfonic acid and sulfuric acid by distillation with at least three functional steps and the use of said methanesulfonic acid.Type: GrantFiled: July 28, 2020Date of Patent: May 26, 2026Assignee: BASF SEInventors: Marina-Eleni Stavrou, Marcus Bechtel, Rosario Mazarro Berdonces, Frank Piepenbreier, Chee Jian Chan, Bjoern Kaibel, Andreas Kempter
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Patent number: 12616959Abstract: The present invention relates to the use of a catalyst made of rhenium oxide supported by cerium oxide, with formula ReOx/CeO2 (I), for catalyzing the deoxydehydration of glycerol to allyl alcohol, the reaction being carried out under heterogeneous conditions in the presence of at least one aliphatic alcohol; and to a method for producing allyl alcohol from glycerol in the presence of the catalyst.Type: GrantFiled: March 24, 2021Date of Patent: May 5, 2026Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFQUE, CENTRALE LILLE INSTITUT, UNIVERSITÉ DE LILLEInventors: Benjamin Katryniok, Karen Silva, Marcia Araque
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Patent number: 12611656Abstract: A method for preparing a molybdenum-bismuth-based composite metal oxide.Type: GrantFiled: August 17, 2021Date of Patent: April 28, 2026Assignee: LG CHEM, LTD.Inventors: Hyunsub Lim, Byung Yul Choi, Young Hyun Choe, Dong Woo Seo, Hyeonho Joo, Youngju Choi, Saeha Lee, Minsu Kim
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Patent number: 12606507Abstract: A method for preparing 1,2-propanediol involves reacting propene with hydrogen peroxide in the presence of a catalyst mixture, containing a phase transfer catalyst and a heteropolytungstate, in a liquid reaction mixture containing an aqueous phase with a maximum apparent pH of 6 and an organic phase. The method then involves separating the reaction mixture into an aqueous phase (Pa) containing 1,2-propanediol and formic acid and an organic phase (Po); recycling at least part of the separated organic phase (Po) to the reaction; contacting at least a part of the separated aqueous phase (Pa) with a palladium catalyst; and recovering 1,2 propanediol from the aqueous phase provided by the contacting. The contacting of at least a part of the separated aqueous phase (Pa) with the palladium catalyst reduces the content of formic acid.Type: GrantFiled: October 7, 2021Date of Patent: April 21, 2026Assignee: Evonik Operations GmbHInventors: Holger Wiederhold, David Bolz, Jürgen Glenneberg
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Patent number: 12606514Abstract: The present disclosure relates to an isomerization method of a cyclohexane dicarboxylic acid (CHDA) and, more specifically, to a method for preparing a trans-cyclohexane dicarboxylic acid (t-CHDA) from a cis-cyclohexane dicarboxylic acid (c-CHDA) by means of catalytic isomerization. Particularly, an embodiment of the present disclosure provides a method for preparing, in high efficiency and high yield and at a low cost, a CHDA having a high t-CHDA content from a CHDA mainly containing c-CHDA, by using an isomerization catalyst containing zirconia and having a BET specific surface area of 50 m2/g or more.Type: GrantFiled: October 27, 2020Date of Patent: April 21, 2026Assignee: HANWHA SOLUTIONS CORPORATIONInventors: Jong Kwon Lee, Namjin Jang, Eun Jeong Kim, Sun Uk Lee