Abstract: Pantropic neurotrophic factors which have multiple neurotrophic specificities are provided. The pantropic neurotrophic factors of the present invention are useful in the treatment of neuronal disorders. Nucleic acids and expression vectors encoding the pantropic neurotrophins are also provided.
Type:
Grant
Filed:
May 12, 1995
Date of Patent:
March 17, 1998
Assignee:
Genentech, Inc.
Inventors:
Roman Urfer, Leonard G. Presta, John W. Winslow