Abstract: The composition contains: an antiinflammatory effective amount of piroxicam; an amount of tetrahydroxypropylethylenediamine sufficient to solubilize the piroxicam in the composition; an amount of C.sub.2 -C.sub.6 alkylene glycol, or mixture thereof, sufficient to detackify the composition and provide humectancy; about 0.2% to about 2% carbomer; about 30% to about 60% C.sub.2 -C.sub.4 alkanol; and water qs to 100%. Hydroxypropylcellulose can be added to the composition.