Abstract: The invention provides methods and compositions for treatment of bacterial infections. Methods of the invention include administration of dalbavancin for treatment of a bacterial infection, in particular a Gram-positive bacterial infection of skin and soft tissue. Dosing regimes include once weekly administration of dalbavancin, which often remains at therapeutic levels in the bloodstream for at least one week, providing prolonged therapeutic action against a bacterial infection.
Type:
Grant
Filed:
November 14, 2003
Date of Patent:
May 31, 2005
Assignee:
Vicuron Pharmaceuticals Inc.
Inventors:
Marco Cavaleri, Daniela Jabes, Timothy Henkel, Adriano Malabarba, Giorgio Mosconi, Martin Stogniew, Richard J. White