Patents Examined by Elizabeth A. Hanley
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Patent number: 4743402Abstract: A sunflower seed is disclosed which has both a high oleic acid content and a low linoleic acid content. Also disclosed is a sunflower seed which has a white or gray seed coat and which contains approximately 80% or greater by weight of oleic acid. Also described are novel sunflowers for producing the disclosed seed and an oil product derived from the seed.Type: GrantFiled: August 26, 1985Date of Patent: May 10, 1988Assignee: SIGCO Research Inc.Inventor: Gerhardt N. Fick
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Patent number: 4741738Abstract: A process for the sulfonation of certain fat and oil mixtures, the product of such process, and a method for using such product as a leather tanning stuffing agent, the certain fat and oil mixtures comprising (A) 20-80% by weight of at least one C.sub.8-24 -fatty acid glycerol ester having an iodine number above 20, and (B) the balance q.s. to 100% by weight of at least one C.sub.1-4 -aliphatic monoalcohol ester of a C.sub.8-24 -fatty acid having an iodine number of 50-100.Type: GrantFiled: May 21, 1987Date of Patent: May 3, 1988Assignee: Henkel Kommanditgesellschaft auf AktienInventors: Hans-Herbert Friese, Friedrich Pieper
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Patent number: 4736065Abstract: A compound of Formula I: ##STR1## wherein: Ar represents a polynuclear carboxyclic or heterocyclic fused ring system having at least one carbocylic or heterocyclic ring of aromatic character, the polynuclear ring system optionally carrying one or more of the substituents halogen, C.sub.1 -C.sub.6 alkyl --CF.sub.3, or --OCF.sub.y H.sub.3-y, wherein y is 0-3;n is 0 or 1 and m is 1-11Z represents a group of Formula: ##STR2## wherein: R.sub.A and R.sub.B which may be identical or different each represent hydrogen or methyl;R.sub.C represents methyl;R.sub.D represents methyl, ethyl, n-propyl, isopropyl, t-butyl, or vinyl; andR.sub.E represents hydrogen or methyl or wherein:R.sub.C and R.sub.D together with C.sub..beta. form a cyclopropane or a cyclobutane ring or goether form a methylene group (.dbd.CH.sub.2) or wherein:R.sub.A and R.sub.B together with C.sub..alpha. and C.sub..beta. form a cyclobutane ring.Type: GrantFiled: September 17, 1986Date of Patent: April 5, 1988Assignee: National Research Development CorporationInventors: Michael Elliott, Norman F. Janes, David A. Pulman, Diana M. Johnson
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Patent number: 4732853Abstract: Racemic carboxylic acid esters of epoxy alcohols are enantio selectively hydrolyzed with hydrolytic enzymes to provide chiral epoxy alcohol and chiral unhydrolyzed ester.Type: GrantFiled: November 21, 1984Date of Patent: March 22, 1988Assignee: President and Fellows of Harvard CollegeInventors: George M. Whitesides, Wolfgang Ladner
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Patent number: 4721811Abstract: An improved process for selectively forming aliphatic polyamines from aliphatic polynitriles having 2 to 3 atoms between cyano groups by reacting aliphatic polynitrile, with hydrogen in the presence of a primary or secondary amine, through a fixed bed reactor while continuously contacting the reactants with granular Raney cobalt packed therein.Type: GrantFiled: August 26, 1985Date of Patent: January 26, 1988Assignee: W. R. Grace & Co.Inventors: Martin B. Sherwin, Shu-Chieh P. Wang, Stewart R. Montgomery
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Patent number: 4721810Abstract: Aromatic amines are alkylated by reaction with an acyclic ether or an unstrained cyclic ether in the presence of a B-subgroup metal oxide alkylation catalyst, preferably a Group IV-B metal oxide with or without a minor proportion of a Group VI-B or Group VIII metal oxide, so that alkylation of the aromatic amine occurs. Under most reaction conditions ether alkylating agents such as diethyl ether not consumed in the alkylation reaction pass through the reaction zone undecomposed and thus can be readily recovered for recycle or other use.Type: GrantFiled: June 6, 1984Date of Patent: January 26, 1988Assignee: Ethyl CorporationInventor: Duane C. Hargis
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Patent number: 4719313Abstract: Gem-dihalo and gem-tetrahalo-1,12-diamino-4,9-diaza-dodecane derivatives useful as antiproliferative or antitumor agents.Type: GrantFiled: February 12, 1986Date of Patent: January 12, 1988Assignee: Merrell Dow Pharmaceuticals Inc.Inventors: Fritz Gerhart, Pierre Mamont
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Patent number: 4713200Abstract: Pesticidal compounds, their production, formulation into pesticidal compositions and use against pests, particularly insects and acarines.Type: GrantFiled: March 29, 1985Date of Patent: December 15, 1987Assignee: Burroughs Wellcome Co.Inventor: Robert J. Blade
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Patent number: 4708936Abstract: Process for the continuous production of L-carnitine by the microbiological method. A microorganism of the strain DSM No. 3225 (HK 1331b) type is cultivated in a bioreactor with crotonobetaine and/or .gamma.-butyrobetaine in the presence of a growth substrate. The culture fluid passes outside of the bioreactor in a circulation in which a separation of the cell is carried out. A quantity of cell-free solution, which is as large as the amount fed to the bioreactor as a substrate, is withdrawn from the bioreactor. The L-carnitine is separated from the cell-free solution.Type: GrantFiled: March 29, 1985Date of Patent: November 24, 1987Assignee: Lonza Ltd.Inventors: Hans Kulla, Pavel Lehky, Armand Squaratti
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Patent number: 4705752Abstract: Process for the enzymatic hydrolysis of a D-.alpha.-amino-acid amide to the corresponding D-.alpha.-amino-acid, wherein an aqueous solution of the D-.alpha.-amino-acid amide is contacted with an aminoacylamidase-containing preparation obtained from a culture of Rhodococcus erythropolis or a mutant thereof and the D-.alpha.-amino-acid is subsequently recovered from the hydrolysate obtained.Type: GrantFiled: September 25, 1985Date of Patent: November 10, 1987Assignee: Stamicarbon B.V.Inventors: Wilhelmus H. J. Boesten, Maria J. H. Cals
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Patent number: 4702864Abstract: 1-Thioether-1-acylaminophosphatidylcholine compounds are structural analogs of platelet activating factor and useful for inhibition of phospholipase A.sub.2, reduction of blood pressure, and alleviation of inflammation.Type: GrantFiled: July 16, 1986Date of Patent: October 27, 1987Assignee: E. I. Du Pont de Nemours and CompanyInventors: Ronald L. Magolda, Pasquale N. Confalone, Paul R. Johnson
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Patent number: 4694105Abstract: Herbicidal and plant growth regulating 3-alkoxyamino- and 3-polyalkoxyamino-2'-chloro-4-nitro-4'-trifluoromethyldiphenyl ethers of formula I ##STR1## wherein each of A, A', A" and A'" is an identical or different C.sub.1 -C.sub.4 alkylene radical which may be straight chain or branched; n is a value from 1 to 5; each of n', n" and n'" is zero or a value from 1 to 5; R is a C.sub.1 -C.sub.4 alkyl radical or a C.sub.1 -C.sub.4 alkylcarbonyl radical, which alkyl radicals may be substituted by halogen or cyano, or is a benzoyl or phenylsulfonyl radical which may be substituted by halogen, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 haloalkyl, C.sub.1 -C.sub.4 haloalkoxy or nitro, or, if A-O is not oxyethylene and/or if the sum of n+n'+n"+n'" is greater than 1, R is also hydrogen; R.sub.1 is hydrogen, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 hydroxyalkyl, C.sub.2 -C.sub.8 alkoxyalkyl, C.sub.1 -C.sub.4 alkylcarbonyl or C.sub.1 -C.sub.4 haloalkylcarbonyl, which radicals R and R.sub.Type: GrantFiled: December 10, 1984Date of Patent: September 15, 1987Assignee: Ciba-Geigy CorporationInventor: Dieter Durr
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Patent number: 4690784Abstract: This invention provides a process for preparing a phosphatidylcholine derivative represented by the formula ##STR1## wherein R represents straight- or branched-chain andsaturated or unsaturated hydrocarbon group, the process comprising the steps of(i) providing a suspension or solution of glycerophosphatidylcholine and a carrier in a solvent and removing the solvent from the suspension or solution by distillation to obtain a powder, and(ii) reacting the glycerophosphatidylcholine present in the powder with an acid anhydride or acid halide in a solvent and in the presence of a basic catalyst to acylate the glycerophosphatidylcholine.Type: GrantFiled: May 28, 1985Date of Patent: September 1, 1987Assignee: Nippon Fine Chemical Co., Ltd.Inventors: Yukihiro Nanba, Toshiyuki Sakakibara
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Patent number: 4689182Abstract: Novel benzoic acid or benzoic acid ester derivatives, pharmaceutical compositions and methods of use thereof are the present invention. Utility is for the treatment of arthritis, asthma, Raynaud's disease, inflammatory bowel disorders, trigeminal or herpetic neuralgia, inflammatory eye disorders, psoriasis, dental pain, and headaches, particularly vascular headache, such as migraine, cluster, mixed vascular syndromes, as well as nonvascular, tension headaches.Type: GrantFiled: December 20, 1985Date of Patent: August 25, 1987Assignee: Warner-Lambert CompanyInventors: Michael F. Rafferty, Graham Johnson