Patents Examined by Elizabeth A. Robinson
  • Patent number: 11506673
    Abstract: A method for measuring bilirubin concentration in a sample includes preparing a sensing element, where the sensing element may include a plurality of carbon dots, adding the sample to the sensing element, where the sample may include a plurality of bilirubin molecules, obtaining a first grayscale image of the sensing element under ultra-violet (UV) irradiation, irradiating visible light with a wavelength between 470 nm and 490 nm on the sensing element, obtaining a second grayscale image of the sensing element under ultra-violet (UV) irradiation, calculating a light intensity difference by calculating a difference between a first average light intensity of the first grayscale image and a second average light intensity of the second image, and determining the bilirubin concentration based on a correlation between the bilirubin concentration and the light intensity difference.
    Type: Grant
    Filed: November 18, 2019
    Date of Patent: November 22, 2022
    Inventors: Hamed Golmohammadi Ghane, Raziyeh Sadat Tabatabaee, Seyyed Hamid Ahmadi
  • Patent number: 11498077
    Abstract: A histologic tissue sample support device includes a tissue cassette, a frame, and a lid. The tissue cassette has a recess including a body with at least one side wall and a bottom wall and is formed of material that can be successfully sectioned in a microtome and is resistant to degradation from solvents and chemicals used to fix, process and stain tissue. The tissue cassette is movably coupled to the frame by a frame-cassette connector. The lid is coupled to a peripheral portion of the frame by a lid-frame connector. The lid and the tissue cassette are capable of moving from a first position to a second position with respect to the frame, and in the second position the bottom wall and at least a portion of the side wall extend beyond a bottom edge of the frame for sectioning in a microtome.
    Type: Grant
    Filed: November 12, 2019
    Date of Patent: November 15, 2022
    Assignee: BioPath Automation, LLC
    Inventor: Warren P. Williamson, IV
  • Patent number: 11499966
    Abstract: A digitally encoded microflake includes a polymer layer, which has a top surface and a bottom surface substantially parallel to the top surface. At least one of the top surface and the bottom surface is to be coupled to target-specific probes for bonding with a target analyte. The microflake is identified by a binary sequence of bits encoded by an edge outline on a plane substantially parallel to the top surface and the bottom surface. The bits in the binary sequence are encoded at respective predefined locations surrounding the edge outline.
    Type: Grant
    Filed: May 12, 2022
    Date of Patent: November 15, 2022
    Assignee: WinMEMS Technologies Co., Ltd.
    Inventors: Chih-Hsiang Lai, Wen-Ching Lai
  • Patent number: 11426723
    Abstract: A system includes a fluidic device, a flow control valve, a first reagent fluid reservoir fluidly connectable to the fluidic device by the flow control valve, a first fluid buffer reservoir fluidly connectable to the fluidic device by the flow control valve, and a common fluid buffer source fluidly connectable to the fluidic device by the flow control valve. The flow control valve permits flow comprising: (i) flow from the first reagent fluid reservoir to the fluidic device, (ii) flow from the common fluid buffer source to the fluidic device, (iii) flow from the fluidic device to the first fluid buffer reservoir, (iv) flow from the first reagent fluid reservoir to the fluidic device, and (v) flow from the first fluid buffer reservoir to the fluidic device.
    Type: Grant
    Filed: September 26, 2019
    Date of Patent: August 30, 2022
    Assignee: Illumina, Inc.
    Inventors: Wesley A. Cox-Muranami, Kay Klausing, Bradley Kent Drews, Nicholas Watson, Jennifer Olivia Foley, Murphy Hitchcock, Paul Sangiorgio, Sz-Chin Steven Lin
  • Patent number: 11378571
    Abstract: Embodiments of the present disclosure include methods and systems for detecting the presence of endotoxins in filters. For example, embodiments of the present disclosure are directed to methods and systems for improving in-process controls by detecting undesirable quantities of endotoxins in filters containing naturally-sourced materials prior to using those filters in the production of formulated drug substances.
    Type: Grant
    Filed: April 26, 2019
    Date of Patent: July 5, 2022
    Assignee: Regeneron Pharmaceuticals, Inc.
    Inventors: Nathan Mao, Annamarie Cruz, Bernhard Schilling, Scott Carver
  • Patent number: 11366109
    Abstract: A digitally encoded microflake includes a polymer layer, which has a top surface and a bottom surface substantially parallel to the top surface. At least one of the top surface and the bottom surface is to be coupled to target-specific probes for bonding with a target analyte. The microflake is identified by a binary sequence of bits encoded by an edge outline on a plane substantially parallel to the top surface and the bottom surface. The bits in the binary sequence are encoded at respective predefined locations surrounding the edge outline.
    Type: Grant
    Filed: October 15, 2019
    Date of Patent: June 21, 2022
    Assignee: WinMEMS Technologies Co., Ltd.
    Inventors: Chih-Hsiang Lai, Wen-Ching Lai
  • Patent number: 11352325
    Abstract: Reagents comprising MS active, fluorescent molecules with an activated functionality for reaction with amines useful in tagging biomolecules such as N-glycans and uses thereof are taught and described. In particular embodiments, the MS active, fluorescent molecules are of the compound of the Formula III or of the Formula IV where R1, R2 and R3 are defined herein.
    Type: Grant
    Filed: January 25, 2016
    Date of Patent: June 7, 2022
    Assignee: Waters Technologies Corporation
    Inventors: Darryl W. Brousmiche, Matthew A. Lauber
  • Patent number: 11192667
    Abstract: Various embodiments provide multi-layered self-healing materials, capable of repairing puncture damage. The multi-layered self-healing materials, capable of repairing puncture damage of the various embodiments may be constructed by sandwiching a reactive (e.g., oxygen sensitive) liquid monomer formulation between two solid polymer panels, such as a polymer panel of Barex 210 IN (PBG) serving as the front layer panel and a polymer panel of Surlyn® 8940 serving as the back layer panel. The various embodiments may provide methods to produce multi-layered healing polymer systems. The various embodiments may provide a two-tier, self-healing material system that provides a non-intrusive capability to mitigate mid to high velocity impact damage in structures.
    Type: Grant
    Filed: December 15, 2015
    Date of Patent: December 7, 2021
    Assignee: United States of America as represented by the Administrator of NASA
    Inventors: Keith L. Gordon, Scott R. Zavada, Timothy F. Scott
  • Patent number: 11142654
    Abstract: A composition for applying a clear or translucent and colorless or nearly colorless emissive coating on a metallic surface comprising in a dispersion a) 50 to 300 g/L of at least one of clear or translucent organic polymeric substances of a binder, and b) 30 to 300 g/L of sheet silicate pigments having a TE value for the thermal emissivity of at least 0.40, having a particle size distribution of which d50 is in the range of 0.3 to 80 ?m. Processes for applying the composition and elements prepared therefrom are also disclosed.
    Type: Grant
    Filed: November 3, 2010
    Date of Patent: October 12, 2021
    Assignee: Chemetall GmbH
    Inventors: Noel Smith, Charles J. Gruszka, Aaron Thompson, Michael Deemer
  • Patent number: 11111398
    Abstract: Methods and compositions related to subsurface modified silica materials are described. The silica materials include silicon- and carbon-containing groups covalently bonded to the silicon-oxygen matrix. The silica materials have tunable permeability, modulus, hardness, flexibility, and elongation. The silica materials are suitable for use as polymer fillers and as functional coatings.
    Type: Grant
    Filed: January 11, 2017
    Date of Patent: September 7, 2021
    Assignee: International Business Machines Corporation
    Inventors: Brandon M. Kobilka, Joseph Kuczynski, Jacob T. Porter, Jason T. Wertz
  • Patent number: 11078312
    Abstract: A cross-linked polymer composition includes a cross-linked polyolefin. Peroxide in an amount of less than 35 mmol —O—O—/kg polymer composition may be included in the polymer composition prior to crosslinking the polyolefin. Suitable polyolefins that can be cross-linked in the polymer composition include an unsaturated LDPE homopolymer and an unsaturated LDPE copolymer of ethylene with one or more comonomers. Such unsaturated LDPE polymer can contain vinyl groups, and the total amount of vinyl groups present in the unsaturated LDPE can be higher than 0.05/1000 carbon atoms. The cross-linked polymer composition can be used, for example, in producing a cross-linkable and cross-linked article such as a cross-linkable and cross-linked direct current (DC) or other type of power cable.
    Type: Grant
    Filed: November 3, 2010
    Date of Patent: August 3, 2021
    Assignee: BOREALIS AG
    Inventors: Annika Smedberg, Birgitta Kallstrand, Ulf Nilsson, Per-Ola Hagstrand, Villgot Englund, Gustavo Dominguez, Carl-Olof Olsson, Liu Rongsheng, Marc Jeroense
  • Patent number: 11037696
    Abstract: A transparent electrode including: a first layer including a thermosetting copolymer including a first repeating unit having an aromatic moiety as a pendant group or incorporated in a backbone of the copolymer and a second repeating unit capable of lowering a curing temperature, a combination of a first polymer including the first repeating unit and a second polymer including the second repeating unit, or a combination thereof; a second layer disposed directly on one side of the first layer, wherein the second layer includes graphene; and a third layer disposed on the second layer, wherein the third layer includes an electrically conductive metal nanowire.
    Type: Grant
    Filed: November 4, 2016
    Date of Patent: June 15, 2021
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Hyeon Cheol Park, Youngjin Cho, Daejin Yang, Chan Kwak, Kwanghee Kim, Weonho Shin, Yun Sung Woo
  • Patent number: 10914009
    Abstract: A non-phosphate coated metal material for plastic working includes a metal material, a coating layer formed on a surface of the metal material, and a lubrication layer on the coating layer. The coating layer includes calcium tetraborate. A method for manufacturing a non-phosphate coated metal material includes a pre-treatment process to remove foreign matters or scale from a surface of a metal material, a coating treatment process to form a coating layer on the surface of the metal material by dipping the metal material, which is subject to the pre-treatment process, into a coating agent, and a lubrication treatment process to form a lubrication layer on the coating layer through the contact between the coated metal material and a lubricating agent. The coating agent includes a non-phosphate treatment solution including at least one borate selected from sodium tetraborate and a hydrate thereof, sodium nitrite, calcium hydroxide, and water.
    Type: Grant
    Filed: July 28, 2015
    Date of Patent: February 9, 2021
    Assignee: HAN YOUNG STEEL WIRE CO., LTD.
    Inventor: Eun Seok Choi
  • Patent number: 10908322
    Abstract: The claimed invention provides an antistatic hard coat film that is extremely excellent in white muddiness resistance and antistatic properties and sufficiently prevents an interference fringe pattern. The claimed invention provides an antistatic hard coat film including a triacetyl cellulose substrate and a hard coat layer formed on the triacetyl cellulose substrate, the hard coat layer including an antistatic agent, a (meth)acrylate resin, and a polymer of a (meth)acrylate monomer, the triacetyl cellulose substrate including a permeation layer formed by permeation of the (meth)acrylate monomer from the hard coat layer side of the interface toward the opposite side of the hard coat layer, the antistatic hard coat film satisfying Formulas (1), (2), and (3): 3 ?m?T?18 ?m??Formula (1) 0.3T?t?0.9T??Formula (2) 2 ?m?T?t?11 ?m??Formula (3) where T denotes the total thickness (?m) of the permeation layer and the hard coat layer, and t denotes the thickness (?m) of the permeation layer.
    Type: Grant
    Filed: September 6, 2011
    Date of Patent: February 2, 2021
    Assignee: DAI NIPPON PRINTING CO., LTD.
    Inventors: Mayu Youki, Tomoyuki Horio, Yoshihiro Nishimura, Mariko Hayashi, Yuya Inomata, Hiroshi Nakamura
  • Patent number: 10886037
    Abstract: A conductor includes (i) a substrate, (ii) a transparent conductive film formed on the substrate and including a silver nanowire, (iii) a metal film formed over the transparent conductive film such that at least a portion thereof overlaps the transparent conductive film, and (iv) a buffer film provided between the transparent conductive film and the metal film, the buffer film having adhesion to each of the transparent conductive film and the metal film, and not impeding conductivity between the transparent conductive film and the metal film. Preferably, the buffer film is formed of an organic material having respective functional groups capable of bonding to the transparent conductive film and the metal film.
    Type: Grant
    Filed: October 24, 2017
    Date of Patent: January 5, 2021
    Assignee: Alps Alpine Co., Ltd.
    Inventors: Yui Abe, Yoshihiro Taguchi, Mitsuo Bito, Yoshiyuki Asabe, Yasuyuki Kitamura, Tomoyuki Yamai, Koji Oguma, Tomofumi Oba
  • Patent number: 10829894
    Abstract: A foldable paper-based substrate coated with primer coat and top coat. Primer coat comprises a wax-free aqueous dispersion characterized in that a dry film thereof has a flexibility of at least 1 100% for a film thickness from about 1.0 to about 2.5 mm. Top coat is blocking resistant and comprises an aqueous dispersion of a polymer providing water resistance, grease or oil resistance, heat resistance, odor barrier, moisture barrier and/or heat sealability to the paper-based product. The top coat aqueous dispersion is characterized in that a dry film thereof has a flexibility of at least 570% for a film thickness from about 1.5 to about 2.5 mm. A process for preparing the coated foldable paper-based substrate comprises applying the primer coat to the surface of the paper-based substrate, applying the top coat and drying the coats. The primer coat may be dried before application of the top coat.
    Type: Grant
    Filed: July 14, 2014
    Date of Patent: November 10, 2020
    Assignee: Cascades Sonoco Inc.
    Inventor: Yvon Mongrain
  • Patent number: 10781036
    Abstract: A glass roll includes a glass film formed by a downdraw method. The glass film is wound into a roll using a winding roller in a state in which front and back glass surfaces of the glass film formed in the forming operation are exposed, and during the winding operation, the glass film is superposed on a separable protective sheet. The protective sheet extends beyond both sides in a width direction of the glass film. The protective sheet can further be wound on an outer peripheral surface of the glass film by winding only the protective sheet from a trailing end of the glass film in a winding direction of the glass film.
    Type: Grant
    Filed: July 10, 2014
    Date of Patent: September 22, 2020
    Assignee: NIPPON ELECTRIC GLASS CO., LTD.
    Inventors: Masahiro Tomamoto, Michiharu Eta, Hidetaka Oda, Tatsuya Takaya, Yasuo Yamazaki, Hiroshi Takimoto, Shinichi Ishibashi, Keiji Takagi, Daisuke Nagata, Takahide Nakamura, Toru Sakurabayashi, Katsutoshi Fujiwara, Mitsuharu Noda, Yasuhiko Ogiso, Takahide Fujii
  • Patent number: 10781133
    Abstract: A scratch-resistant amorphous and transparent AlSiN cover layer on a glass or glass ceramic substrate is provided. The cover layer has a low surface roughness and has sliding properties with respect to pots and other items. The cover layer is transparent in the visible light range and also largely transparent in the infrared range and has good chemical resistance to salted water burn-in.
    Type: Grant
    Filed: September 4, 2015
    Date of Patent: September 22, 2020
    Assignee: SCHOTT AG
    Inventors: Thorsten Damm, Christian Henn
  • Patent number: 10696880
    Abstract: Provided are a polyester-based pressure-sensitive adhesive composition having high wetting ability and superior adherability and light peelability, and a pressure-sensitive adhesive sheet produced with such a pressure-sensitive adhesive composition. The polyester-based pressure-sensitive adhesive composition includes a polyester obtained by polycondensation of a difunctional or polyfunctional carboxylic acid and a diol; a fatty acid ester; and a crosslinking agent, wherein the polyester has a weight average molecular weight of 8,500 to 50,000, and the fatty acid ester has no additional functional group and has a molecular weight of 200 to 700. The polyester-based pressure-sensitive adhesive composition contains 10 to 150 parts by weight of the fatty acid ester based on 100 parts by weight of the polyester.
    Type: Grant
    Filed: January 16, 2015
    Date of Patent: June 30, 2020
    Assignee: NITTO DENKO CORPORATION
    Inventors: Satomi Yoshie, Shigeki Ishiguro, Akiko Tanaka
  • Patent number: 10675839
    Abstract: A fiber reinforced resin product includes at least one layer of a first fiber reinforced resin layer in which first reinforcing fibers having a large breaking elongation are contained in a layered form, and at least one layer of a second fiber reinforced resin layer in which second reinforcing fibers having a smaller breaking elongation and a larger tensile strength in comparison with those of the first fiber reinforced resin layer are contained in a layered form. The second fiber reinforced resin layer is positioned outwardly of the first fiber reinforced resin layer. Furthermore, the first fiber reinforced resin layer and the second fiber reinforced resin layer share a single matrix resin in common.
    Type: Grant
    Filed: March 21, 2018
    Date of Patent: June 9, 2020
    Assignee: HONDA MOTOR CO., LTD.
    Inventor: Takeshi Ohara