Abstract: A composition is provided for the treatment of contagious equine metritis, a contagious venereal disease of horses. The composition appears to function as a biological inhibitor and has antibacterial and antifungal activity when applied to the normal flora and secretions of the epidermis and mucous membranes. Also, the composition has antipruritic and anti-inflammatory activity. The composition is efficacious in the treatment of lesions produced by bacteria, fungi, allergies, viruses, trauma, and burns to the epidermis, dermis, muscles and mucous membranes of the surface or in body cavities of animals and man.The composition preferably comprises an aqueous solution of dextrose, citric acid and a buffering mixture of the salts of citric acid and acetic acid to provide an optional pH between 3.0 to 6.5 for various wound lesions.